Doβ-Defensins and Other Antimicrobial Peptides Play a Role in Neuroimmune Function and Neurodegeneration?

The Damage Signals Hypothesis of Alzheimer's Disease Pathogenesis

(2017) Jorge A. Fernández et al.   JOURNAL OF ALZHEIMERS DISEASE

Increased Pro-Inflammatory Response by Dendritic Cells from Patients with Alzheimer's Disease

(2017) Antonio Ciaramella et al.   JOURNAL OF ALZHEIMERS DISEASE

Brain Alterations in Autoimmune and Pharmacological Models of Diabetes Mellitus: Focus on Hypothalamic-Pituitary-Adrenocortical Axis Disturbances

(2017) J. Beauquis et al.   NEUROIMMUNOMODULATION

Inflammatory Mechanisms in Obesity

(2011) Margaret F. Gregor et al.   Annual Review of Immunology

Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF

(2011) Fiona Semple et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Increased Expression of Beta-Defensin 1 (DEFB1) in Chronic Obstructive Pulmonary Disease

(2011) Ellen Andresen et al.   PLoS One

Oligomeric structure of a cathelicidin antimicrobial peptide in dodecylphosphocholine micelle determined by NMR spectroscopy

(2010) Rathi Saravanan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Inducible expression of human β-defensin 2 by Chlamydophila pneumoniae in brain capillary endothelial cells

(2010) Zoltán Tiszlavicz et al.   Innate Immunity

Human  -Defensin 2 and 3 and Their Mouse Orthologs Induce Chemotaxis through Interaction with CCR2

(2010) J. Rohrl et al.   JOURNAL OF IMMUNOLOGY

Epithelial cell-derived antimicrobial peptides are multifunctional agents that bridge innate and adaptive immunity

(2010) Thomas S. McCormick et al.   PERIODONTOLOGY 2000

The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

(2010) Stephanie J. Soscia et al.   PLoS One

The Role of Neuroimmunomodulation in Alzheimer's Disease

(2009) Ricardo B. Maccioni et al.   Annals of the New York Academy of Sciences

Multifunctional host defense peptides: Antimicrobial peptides, the small yet big players in innate and adaptive immunity

(2009) Constance Auvynet et al.   FEBS Journal

Defensins as anti-inflammatory compounds and mucosal adjuvants

(2009) Karl G Kohlgraf et al.   Future Microbiology

Intracerebral Dendritic Cells Critically Modulate Encephalitogenic versus Regulatory Immune Responses in the CNS

(2009) A. L. Zozulya et al.   JOURNAL OF NEUROSCIENCE

Insulin Action on Polyunsaturated Phosphatidic Acid Formation in Rat Brain: An “In Vitro” Model with Synaptic Endings from Cerebral Cortex and Hippocampus

(2009) Sandra E. Zulian et al.   NEUROCHEMICAL RESEARCH

Exacerbation of poststroke dementia by type 2 diabetes is associated with synergistic increases of β-secretase activation and β-amyloid generation in rat brains

(2009) T. Zhang et al.   NEUROSCIENCE

Role of microglia in neuronal degeneration and regeneration

(2009) Lisa Walter et al.   Seminars in Immunopathology

Stress Insulin Resistance is a Marker for Mortality in Traumatic Brain Injury

(2009) Nathan T. Mowery et al.   JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE

Multivariate Analysis of Structural and Diffusion Imaging in Traumatic Brain Injury

(2008) Brian Avants et al.   ACADEMIC RADIOLOGY

Glucose and insulin are needed for optimal defensin expression in human cell lines

(2008) Maayan Barnea et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

(Pre)diabetes, brain aging, and cognition

(2008) Jarbas S. Roriz-Filho et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Coexistences of insulin signaling-related proteins and choline acetyltransferase in neurons

(2008) Hongjuan Wang et al.   BRAIN RESEARCH

Insulin Resistance and Alzheimers Disease: Molecular Links & Clinical Implications

(2008) Karen Neumann et al.   Current Alzheimer Research

Hyperglycaemia and neurological injury

(2008) Amit Prakash et al.   Current Opinion in Anesthesiology

Systemic inflammation exacerbates behavioral and histopathological consequences of isolated traumatic brain injury in rats

(2008) Akira Utagawa et al.   EXPERIMENTAL NEUROLOGY

Structural requirements for antimicrobial versus chemoattractant activities for dermaseptin S9

(2008) Constance Auvynet et al.   FEBS Journal

Transplantation of BMSCs expressing hPDGF-A/hBD2 promotes wound healing in rats with combined radiation-wound injury

(2008) L Hao et al.   GENE THERAPY

Inflammatory signals in dendritic cell activation and the induction of adaptive immunity

(2008) Olivier Joffre et al.   IMMUNOLOGICAL REVIEWS

Human β-defensin 3 binds to hemagglutinin B (rHagB), a non-fimbrial adhesin from Porphyromonas gingivalis , and attenuates a pro-inflammatory cytokine response

(2008) Lindsey C Pingel et al.   IMMUNOLOGY AND CELL BIOLOGY

Host antimicrobial proteins as endogenous immunomodulators

(2008) Markus A. Hölzl et al.   IMMUNOLOGY LETTERS

Evaluation of the effect of human  -defensins on neutrophil apoptosis

(2008) I. Nagaoka et al.   INTERNATIONAL IMMUNOLOGY

Acute Neurodegeneration and the Inflammasome: Central Processor for Danger Signals and the Inflammatory Response?

(2008) George Trendelenburg   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Murine  -defensin 2 promotes TLR-4/MyD88-mediated and NF- B-dependent atypical death of APCs via activation of TNFR2

(2008) A. Biragyn et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Brain-Region-Specific Astroglial Responses In Vitro After LPS Exposure

(2008) Markus Kipp et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Poly (ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation

(2008) Nirmal K. Phulwani et al.   JOURNAL OF NEUROCHEMISTRY

Role of Glial Cells in the Functional Expression of LL-37/Rat Cathelin-Related Antimicrobial Peptide in Meningitis

(2008) Lars-Ove Brandenburg et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Distinct Cellular Patterns of Upregulated Chemokine Expression Supporting a Prominent Inflammatory Role in Traumatic Brain Injury

(2008) Charlotte Israelsson et al.   JOURNAL OF NEUROTRAUMA

Disruption of Bax Protein Prevents Neuronal Cell Death but Produces Cognitive Impairment in Mice following Traumatic Brain Injury

(2008) Roya Tehranian et al.   JOURNAL OF NEUROTRAUMA

Neuroinflammation Associated with Aging Sensitizes the Brain to the Effects of Infection or Stress

(2008) Nathan L. Sparkman et al.   NEUROIMMUNOMODULATION

Delayed glucose treatment improves cognitive function following fluid-percussion injury

(2008) Olga N. Kokiko-Cochran et al.   NEUROSCIENCE LETTERS

Opposing Roles for Reactive Astrocytes following Traumatic Brain Injury

(2008) Melissa D. Laird et al.   NEUROSIGNALS

The Role of Antimicrobial Peptides at the Ocular Surface

(2008) Alison M. McDermott   OPHTHALMIC RESEARCH

Antimicrobial human beta-defensin-2 stimulates migration, proliferation and tube formation of human umbilical vein endothelial cells

(2008) Adone Baroni et al.   PEPTIDES

Cell death in the injured brain: Roles of metallothioneins

(2008) Mie Ø Pedersen et al.   PROGRESS IN HISTOCHEMISTRY AND CYTOCHEMISTRY

Microglia and Astrocyte Activation by Toll-Like Receptor Ligands: Modulation by PPAR-γAgonists

(2008) Catherine Gurley et al.   PPAR Research

Screening of innate immune receptors in neurodegenerative diseases: A similar pattern

(2007) Maryse Letiembre et al.   NEUROBIOLOGY OF AGING

Immunosuppression after traumatic or ischemic CNS damage: It is neuroprotective and illuminates the role of microglial cells

(2007) Nils P. Hailer   PROGRESS IN NEUROBIOLOGY

The role of inflammation in CNS injury and disease

(2006) Sian-Marie Lucas et al.   BRITISH JOURNAL OF PHARMACOLOGY