Article
Chemistry, Physical
Dzmitry H. Zaitsau, Riko Siewert, Andrey A. Pimerzin, Mark Buelow, Christoph Held, Manuel Loor, Stephan Schulz, Sergey P. Verevkin
Summary: Ionic liquids are effectively used for tuning the composition and morphology of nanoparticles or stabilizing agents for nanoparticles in catalytic dehydrogenation processes. The thermodynamic properties of ionic liquids, such as vapor pressures and vaporization enthalpies, play a key role in optimizing these processes.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Chemistry, Physical
Dzmitry H. Zaitsau, Riko Siewert, Andrey A. Pimerzin, Mark Buelow, Christoph Held, Manuel Loor, Stephan Schulz, Sergey P. Verevkin
Summary: Ionic liquids are effectively used for tuning the composition and morphology of nanoparticles or stabilizing agents for catalytic dehydrogenation. By measuring vapor pressures and vaporization enthalpies, certain series of ionic liquids have been identified as suitable for catalytic applications due to their thermal stability. Experimental and theoretical analysis provide insights into the behavior of these ionic liquids during vaporization and decomposition processes.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Review
Engineering, Chemical
Chenqian Xu, Zhenmin Cheng
Summary: Ionic liquids are considered the safest solvents in high-temperature applications due to their non-flammable properties, with thermogravimetric analysis being extensively used for studying their thermal stability. Isoconversional methods are found to be superior to Arrhenius methods in calculating activation energy, and the use of compensation effect and master plots is suggested for pre-exponential factor calculation. The structure of cations has some influence on thermal stability, but anions play a larger role. Developing dicationic ILs can lead to enhanced thermal stability.
Article
Biochemistry & Molecular Biology
Wanting Cheng, Feng Xian, Zhanluo Zhou, Kun Hu, Jing Gao
Summary: This study investigates the solubility and stability of carotenoids in phosphonium- and ammonium-based ionic liquids (ILs). The results show that carotenoids have higher solubility in acidic ILs compared to alkaline ILs, with an optimal pH of 6. Among the ILs studied, tributyloctylphosphonium chloride ([P-4448]Cl) exhibits the highest solubility. Higher temperatures improve solubility but decrease storage stability, while water content has no significant effect on carotenoid stability but reduces solubility. This study provides guidance for selecting appropriate solvents for carotenoid extraction and storage.
Article
Chemistry, Physical
K. J. Jisha, Ramesh L. Gardas
Summary: The study shows that ionic liquids (ILs) based on 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) can act as suitable solvents and have a positive impact on hemoglobin (Hb). Spectroscopic analysis reveals that these ILs exhibit Hb-friendly behavior at lower concentrations, preserving the absorbance and fluorescence behavior of the protein molecule and increasing its solubility.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Chemistry, Multidisciplinary
J. Alberto Arroyo-Valdez, Gonzalo Viramontes-Gamboa, Roberto Guerra-Gonzalez, Mariana Ramos-Estrada, Enrique Lima, Jose L. Rivera
Summary: Molecular dynamics simulations show that ionic liquids containing alkylated imidazoles exhibit a bimodal distribution of cation conformations (folded/unfolded), where the concentration of folded cations increases with temperature, reducing liquid cohesivity. At the interface, an outermost layer of cations can tilt towards and cover a layer of adsorbed anions, resulting in stability in transverse directions and instability in the normal direction at temperatures around thermal instability, limiting the rate of vaporization of neutral ion pairs.
Article
Chemistry, Physical
Asghar Shirani, Jihung Lee, Diana Berman
Summary: Ionic liquid-based solid polymer electrolytes with stable thermal properties and low electrical resistivity were evaluated in this study. PEGDA was chosen as the polymer component for its uniform SPE formation and better thermal stability compared to Nafion. Six IL candidates were tested to investigate the effect of their hydrophobicity/hydrophilicity on the resulting SPE, with BMIM.MS showing the highest gas absorption capacity.
JOURNAL OF CHEMICAL PHYSICS
(2021)
Article
Polymer Science
Josh D. Wolfgang, Jennifer L. Dysart, Matthew Laskoski
Summary: Phthalonitrile (PN) polymers are high-temperature thermosetting resins with long cure-times hindering their use in certain applications. The addition of dicyanamide-based ionic liquid and aromatic amine allowed for lower cure temperatures and shorter cure times. The results showed significant improvements in the curing process and properties of the PN resins.
JOURNAL OF APPLIED POLYMER SCIENCE
(2023)
Article
Chemistry, Physical
Woonghee Choi, Gi Hyeon Sung, Woong-Ryeol Yu, Dong Wook Kim
Summary: The volatility of liquid electrolytes is a major obstacle in the fabrication of efficient and safe lithium-ion batteries. A novel ionic liquid crosslinker was synthesized and used for thermal crosslinking to prepare a gel polymer electrolyte (GPE) with higher thermal stability and ionic conductivity than liquid electrolytes or solid electrolytes.
ACS APPLIED ENERGY MATERIALS
(2022)
Review
Medicine, Research & Experimental
Chunxia Liu, Bin Chen, Wei Shi, Wenlong Huang, Hai Qian
Summary: Ionic liquids (ILs) are nonmolecular compounds composed only of ions, which have a wide range of applications in various fields including pharmaceuticals. ILs have advantages such as wide chemical space, adjustable structures, and high thermal stability, making them potential candidates for drug delivery systems.
MOLECULAR PHARMACEUTICS
(2022)
Article
Chemistry, Physical
Mojtaba Rezaeian, Mohammad Izadyar, Mohammad Reza Housaindokht
Summary: The thermal decomposition mechanisms of amino acid ionic liquids (AAILs) were investigated using density functional theory. The results showed that the SN2 and alkyl rearrangement mechanisms are the most probable routes. The environment polarity plays an important role in the thermal decomposition mechanism, especially in the alkyl rearrangement route.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Thermodynamics
Andong Yu, Xinmiao Liang, Min Hua, Lu Qian, Xuhai Pan, Yiming Jang, Sanming Wang, Juncheng Jiang
Summary: Nitrocellulose, a versatile and thermosensitive material, has caused numerous fire and explosion accidents due to its thermal instability during production, transport, storage, and use. Humectants are commonly used to improve the safety of nitrocellulose. This study evaluated the thermal stability of the ionic liquid 1-butyl-3-methylimidazolium hexafluorophosphate ([Bmim][PF6]) and its ability to serve as a humectant for nitrocellulose. Results showed that [Bmim][PF6] exhibited high thermal stability, inhibited the decomposition of nitrocellulose, and absorbed nitrogen dioxide, thereby improving the safety of nitrocellulose.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2023)
Article
Engineering, Chemical
Evgeny E. Tereshatov, Valerie Mazan, Maria Boltoeva, Charles M. Folden III
Summary: A mathematical model has been developed to explain the solubility of ionic liquids in hydrochloric acid solutions, with extraction constants being estimated. The study shows that the more hydrophilic the cation of the ionic liquid, the more hydrochloric acid is extracted.
SEPARATION AND PURIFICATION TECHNOLOGY
(2021)
Review
Pharmacology & Pharmacy
Mayank Handa, Waleed H. Almalki, Rahul Shukla, Obaid Afzal, Abdulmalik Saleh Alfawaz Altamimi, Sarwar Beg, Mahfoozur Rahman
Summary: Ionic liquids (ILs) have a wide range of applications in the biomedical field, improving drug delivery and effects by enhancing the physicochemical properties of drugs to increase solubility, release, and permeability.
DRUG DISCOVERY TODAY
(2022)
Article
Engineering, Chemical
Ethan A. Finberg, Mark B. Shiflett
Summary: Hydrofluorocarbon refrigerants are being phased out due to their high global warming potential, leading to a demand for new technologies for separating and recycling these refrigerants. Extractive distillation using ionic liquids as entrainers has been found to be effective in separating refrigerant mixtures. By fitting vapor-liquid equilibrium data and developing models in ASPEN Plus, parameters can be optimized to achieve high purity levels for refrigerants.
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2021)
Article
Chemistry, Applied
Yi-Reng Lin, Mei-Fang Huang, You-Ying Wu, Meng-Chieh Liu, Jing-Heng Huang, Ziyu Chen, Yow-Ling Shiue, Chia-En Wu, Shih-Shin Liang
Article
Cell Biology
Wei-Hua Tang, Chao-Ping Wang, Teng-Hung Yu, Pei-Yang Tai, Shih-Shin Liang, Wei-Chin Hung, Cheng-Ching Wu, Sung-Hao Huang, Yau-Jiunn Lee, Shih-Chieh Chen
HISTOCHEMISTRY AND CELL BIOLOGY
(2018)
Article
Biochemical Research Methods
Hugo You-Hsien Lin, Chan-Jung Liang, Meng-Chieh Liu, Mei-Fang Huang, Jung-San Chang, Shih-Shin Liang
JOURNAL OF CHROMATOGRAPHY A
(2018)
Article
Biochemical Research Methods
Mei-Fang Huang, Yi-Reng Lin, Yu-Tzu Chang, Yow-Ling Shiue, Shih-Shin Liang
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
(2018)
Article
Oncology
Pei-Jing Yang, Ming-Feng Hou, Eing-Mei Tsai, Shih-Shin Liang, Chien-Chih Chiu, Fu Ou-Yang, Jung-Yu Kan, Chiung-Yu Peng, Tsu-Nai Wang
Article
Cell Biology
Ren-Jie Wei, Wen-Ren Wu, Cheng-Tang Pan, Chun-Yen Yu, Chien-Feng Li, Lih-Ren Chen, Shih-Shin Liang, Yow-Ling Shiue
JOURNAL OF CELLULAR PHYSIOLOGY
(2019)
Article
Environmental Sciences
Chon-Kit Chou, Hurng-Wern Huang, Chun-Feng Yang, Hans-Uwe Dahms, Shih-Shin Liang, Tsu-Nai Wang, Po-Lin Kuo, Edward Hsi, Eing-Mei Tsai, Chien-Chih Chiu
ENVIRONMENTAL TOXICOLOGY
(2019)
Article
Food Science & Technology
Jia-Feng Chang, Chih-Yu Hsieh, Kuo-Cheng Lu, Yue-Wen Chen, Shih-Shin Liang, Chih-Cheng Lin, Chi-Feng Hung, Jian-Chiun Liou, Mai-Szu Wu
Article
Biochemistry & Molecular Biology
Chih-Chang Hung, Fu-An Li, Shih-Shin Liang, Ling-Feng Wang, I-Ling Lin, Chien-Chih Chiu, Chiu-Hsien Lee, Jeff Yi-Fu Chen
Article
Cell Biology
Chih-Yu Yang, Ting-Wen Chen, Wan-Lun Lu, Shih-Shin Liang, Hsien-Da Huang, Ching-Ping Tseng, Der-Cherng Tarng
Summary: CKD patients show alterations in gut microbiota diversity, which can be treated with synbiotic therapy to reduce harmful bacteria and restore levels similar to healthy controls. ESKD patients have similar levels of indole-producing bacteria compared to healthy controls, but significantly higher blood levels of indoxyl sulfate.
Article
Biochemistry & Molecular Biology
Mahendra Jadhao, Eing-Mei Tsai, Ho-Chun Yang, Yih-Fung Chen, Shih-Shin Liang, Tsu-Nai Wang, Yen-Ni Teng, Hurng-Wern Huang, Li-Fang Wang, Chien-Chih Chiu
Summary: The study revealed that long-term exposure to DEHP can induce acquired multidrug resistance in breast cancer cells, potentially through upregulation of ABC transporters. By inhibiting ABC transporters with tariquidar, drug cytotoxicity can be enhanced, reversing acquired multidrug resistance.
Article
Biochemistry & Molecular Biology
Shih-Shin Liang, Po-Tsun Shen, Yu-Qing Liang, Yi-Wen Ke, Chieh-Wen Cheng, Yi-Reng Lin
Summary: In this study, we used isotopic formaldehyde and sodium cyanoborohydride through reductive amination to label two methyl groups on primary amine for the preparation of standards and internal standards of tryptophan and its metabolites. The derivatized reactions showed high yields and were suitable for manufacturing standards and internal standards. This method created one or two methyl groups on amine to generate different mass unit shifts, providing a useful tool for biomolecules with amine groups. Using serotonin, 5-hydroxytryptophan, and tryptophan as examples, we successfully demonstrated the application of isotopic formaldehyde for generating standards and internal standards. The derivatized method showed good linearity, with coefficients of determination ranging from 0.9938 to 0.9969, and limits of detection and quantification ranging from 1.39 to 15.36 ng/mL.
Article
Oncology
Chien-Feng Li, Wen-Ren Wu, Ti-Chun Chan, Yu-Hui Wang, Lih-Ren Chen, Wen-Jeng Wu, Bi-Wen Yeh, Shih-Shin Liang, Yow-Ling Shiue
CLINICAL CANCER RESEARCH
(2017)
Article
Chemistry, Analytical
Yi-Reng Lin, Chia-En Wu, Mei-Fang Huang, You-Ying Wu, Jing-Heng Huang, Meng-Chieh Liu, Ziyu Chen, You-Ling Shiue, Shih-Shin Liang
CURRENT ANALYTICAL CHEMISTRY
(2017)
Review
Immunology
Chon-Kit Chou, Ya-Ting Yang, Ho-Chun Yang, Shih-Shin Liang, Tsu-Nai Wang, Po-Lin Kuo, Hui-Min David Wang, Eing-Mei Tsai, Chien-Chih Chiu
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
(2018)
Article
Chemistry, Organic
Fuying Zhu, Yamei Lin
Summary: In this study, a low-metal iron-supported catalyst (Fe20/NC-Mg) was reported for the efficient synthesis of quinoxaline compounds, using water as a solvent and without additional bases. The synergistic effect of FeNx site and Mg (OH)2 nanorods in the catalyst played a key role in achieving high yields (82-91%) in 16 examples. The gram-level synthesis and reusability of the catalysts after four cycles demonstrated its industrial application potential.
Article
Chemistry, Organic
Mikhail Kozlov, Alexey Tyurin, Andrey Dmitrenok, Vyacheslav Rusak, Aleksander Fedorov, Igor Zavarzin, Yulia Volkova
Summary: This study presents a novel and practical synthesis method for phosphorus-substituted 1,3,4-thiadiazolines using phosphorylthioformic acid hydrazides and ketones. The protocol demonstrates operational simplicity, availability of reagents, and tolerance towards different functional groups.
Article
Chemistry, Organic
Jisna Jose, Thomas Mathew
Summary: 2-Cyclopentenone and its derivatives are highly esteemed synthetic intermediates with exceptional utility in organic synthesis. They are favored structural motifs in numerous pharmaceutical drugs and natural products, highlighting their significance. The review discusses the various methods used to synthesize cyclopentenones from 2016 to 2023.
