The Biomechanisms of Metal and Metal-Oxide Nanoparticles’ Interactions with Cells

Suppression of nanoparticle cytotoxicity approaching in vivo serum concentrations: limitations of in vitro testing for nanosafety

(2014) Jong Ah Kim et al.   Nanoscale

High Content Analysis Provides Mechanistic Insights on the Pathways of Toxicity Induced by Amine-Modified Polystyrene Nanoparticles

(2014) Sergio Anguissola et al.   PLoS One

Dysregulation of Macrophage Activation Profiles by Engineered Nanoparticles

(2013) Vamsi Kodali et al.   ACS Nano

Integrating zebrafish toxicology and nanoscience for safer product development

(2013) Ki-Tae Kim et al.   GREEN CHEMISTRY

The biomolecular corona is retained during nanoparticle uptake and protects the cells from the damage induced by cationic nanoparticles until degraded in the lysosomes

(2013) Fengjuan Wang et al.   Nanomedicine-Nanotechnology Biology and Medicine

Transferrin-functionalized nanoparticles lose their targeting capabilities when a biomolecule corona adsorbs on the surface

(2013) Anna Salvati et al.   Nature Nanotechnology

Titanium dioxide nanoparticles: a review of current toxicological data

(2013) Hongbo Shi et al.   Particle and Fibre Toxicology

Multidimensional In Vivo Hazard Assessment Using Zebrafish

(2013) Lisa Truong et al.   TOXICOLOGICAL SCIENCES

Use of Metal Oxide Nanoparticle Band Gap To Develop a Predictive Paradigm for Oxidative Stress and Acute Pulmonary Inflammation

(2012) Haiyuan Zhang et al.   ACS Nano

The anti-inflammatory effects of platinum nanoparticles on the lipopolysaccharide-induced inflammatory response in RAW 264.7 macrophages

(2012) Mati Ur Rehman et al.   INFLAMMATION RESEARCH

Biomolecular coronas provide the biological identity of nanosized materials

(2012) Marco P. Monopoli et al.   Nature Nanotechnology

Zeta Potential and Solubility to Toxic Ions as Mechanisms of Lung Inflammation Caused by Metal/Metal Oxide Nanoparticles

(2012) Wan-Seob Cho et al.   TOXICOLOGICAL SCIENCES

Applying quantitative structure–activity relationship approaches to nanotoxicology: Current status and future potential

(2012) David A. Winkler et al.   TOXICOLOGY

Systematic Evaluation of Nanomaterial Toxicity: Utility of Standardized Materials and Rapid Assays

(2011) Stacey L. Harper et al.   ACS Nano

The molecular mechanism of action of bactericidal gold nanoparticles on Escherichia coli

(2011) Yan Cui et al.   BIOMATERIALS

Exploring Quantitative Nanostructure-Activity Relationships (QNAR) Modeling as a Tool for Predicting Biological Effects of Manufactured Nanoparticles

(2011) Denis Fourches et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Persistent adult zebrafish behavioral deficits results from acute embryonic exposure to gold nanoparticles

(2011) Lisa Truong et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Self-Organizing Map Analysis of Toxicity-Related Cell Signaling Pathways for Metal and Metal Oxide Nanoparticles

(2011) Robert Rallo et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Endocytosis and intracellular transport of nanoparticles: Present knowledge and need for future studies

(2011) Tore-Geir Iversen et al.   Nano Today

Mutagenic effects of gold nanoparticles induce aberrant phenotypes in Drosophila melanogaster

(2011) Giuseppe Vecchio et al.   Nanomedicine-Nanotechnology Biology and Medicine

Media ionic strength impacts embryonic responses to engineered nanoparticle exposure

(2011) Lisa Truong et al.   Nanotoxicology

Inflammatory responses of RAW 264.7 macrophages upon exposure to nanoparticles: Role of ROS-NFκB signaling pathway

(2011) Reddy P. Nishanth et al.   Nanotoxicology

Using nano-QSAR to predict the cytotoxicity of metal oxide nanoparticles

(2011) Tomasz Puzyn et al.   Nature Nanotechnology

Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets

(2011) Thomas B. Knudsen et al.   TOXICOLOGY

QSAR modeling of nanomaterials

(2011) Enrico Burello et al.   Wiley Interdisciplinary Reviews-Nanomedicine and Nanobiotechnology

Quantitative Nanostructure−Activity Relationship Modeling

(2010) Denis Fourches et al.   ACS Nano

Penetration of Lipid Membranes by Gold Nanoparticles: Insights into Cellular Uptake, Cytotoxicity, and Their Relationship

(2010) Jiaqi Lin et al.   ACS Nano

Differential stability of lead sulfide nanoparticles influences biological responses in embryonic zebrafish

(2010) Lisa Truong et al.   ARCHIVES OF TOXICOLOGY

Signaling gene cascade in silver nanoparticle induced apoptosis

(2010) P. Gopinath et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

The Immune Toxicity of Titanium Dioxide on Primary Pulmonary Alveolar Macrophages Relies on their Surface Area and Crystal Structure

(2010) Ran Liu et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

A theoretical framework for predicting the oxidative stress potential of oxide nanoparticles

(2010) Enrico Burello et al.   Nanotoxicology

An index for characterization of nanomaterials in biological systems

(2010) Xin-Rui Xia et al.   Nature Nanotechnology

Gold nanoparticles attenuate LPS-induced NO production through the inhibition of NF-κB and IFN-β/STAT1 pathways in RAW264.7 cells

(2010) Ji Su Ma et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Nanoparticle interaction with plasma proteins as it relates to particle biodistribution, biocompatibility and therapeutic efficacy

(2009) Parag Aggarwal et al.   ADVANCED DRUG DELIVERY REVIEWS

Minireview: Nanoparticles and the Immune System

(2009) Banu S. Zolnik et al.   ENDOCRINOLOGY

Interaction of nano-TiO2 with lysozyme: insights into the enzyme toxicity of nanosized particles

(2009) Zhen Xu et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Safety assessment for nanotechnology and nanomedicine: concepts of nanotoxicology

(2009) G. Oberdörster   JOURNAL OF INTERNAL MEDICINE

Structure and Activity of Lysozyme on Binding to ZnO Nanoparticles

(2009) Soumyananda Chakraborti et al.   LANGMUIR

In Caenorhabditis elegans Nanoparticle-Bio-Interactions Become Transparent: Silica-Nanoparticles Induce Reproductive Senescence

(2009) Adam Pluskota et al.   PLoS One

In vitro evaluation of cytotoxicity of engineered metal oxide nanoparticles

(2009) Xiaoke Hu et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Silver nanoparticles induced heat shock protein 70, oxidative stress and apoptosis in Drosophila melanogaster

(2009) Maqusood Ahamed et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Comparison of the Mechanism of Toxicity of Zinc Oxide and Cerium Oxide Nanoparticles Based on Dissolution and Oxidative Stress Properties

(2008) Tian Xia et al.   ACS Nano

Chemical stability of metallic nanoparticles: A parameter controlling their potential cellular toxicity in vitro

(2008) Mélanie Auffan et al.   ENVIRONMENTAL POLLUTION

Surface Modification and Functionalization of Metal and Metal Oxide Nanoparticles by Organic Ligands

(2008) Marie-Alexandra Neouze et al.   MONATSHEFTE FUR CHEMIE

Protein-nanoparticle interactions

(2008) Iseult Lynch et al.   Nano Today

Perturbational profiling of nanomaterial biologic activity

(2008) S. Y. Shaw et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nanoparticle size and surface properties determine the protein corona with possible implications for biological impacts

(2008) M. Lundqvist et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA