Integrating zebrafish toxicology and nanoscience for safer product development

In vivo genome editing using a high-efficiency TALEN system

(2012) Victoria M. Bedell et al.   NATURE

AHR2 Mutant Reveals Functional Diversity of Aryl Hydrocarbon Receptors in Zebrafish

(2012) Britton C. Goodale et al.   PLoS One

Improved Somatic Mutagenesis in Zebrafish Using Transcription Activator-Like Effector Nucleases (TALENs)

(2012) Finola E. Moore et al.   PLoS One

Loss of Slc4a1b Chloride/Bicarbonate Exchanger Function Protects Mechanosensory Hair Cells from Aminoglycoside Damage in the Zebrafish Mutant persephone

(2012) Dale W. Hailey et al.   PLoS Genetics

Use of a High-Throughput Screening Approach Coupled with In Vivo Zebrafish Embryo Screening To Develop Hazard Ranking for Engineered Nanomaterials

(2011) Saji George et al.   ACS Nano

Systematic Evaluation of Nanomaterial Toxicity: Utility of Standardized Materials and Rapid Assays

(2011) Stacey L. Harper et al.   ACS Nano

Developmental toxicity testing for safety assessment: new approaches and technologies

(2011) Thomas B. Knudsen et al.   BIRTH DEFECTS RESEARCH PART B-DEVELOPMENTAL AND REPRODUCTIVE TOXICOLOGY

Zebrafish-As an integrative model for twenty-first century toxicity testing

(2011) Nisha S. Sipes et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Gold nanoparticles in biomedical applications: recent advances and perspectives

(2011) Lev Dykman et al.   CHEMICAL SOCIETY REVIEWS

Cellular toxicity of inorganic nanoparticles: Common aspects and guidelines for improved nanotoxicity evaluation

(2011) Stefaan J. Soenen et al.   Nano Today

Surface charge of gold nanoparticles mediates mechanism of toxicity

(2011) Nicole M. Schaeublin et al.   Nanoscale

Media ionic strength impacts embryonic responses to engineered nanoparticle exposure

(2011) Lisa Truong et al.   Nanotoxicology

Targeted gene disruption in somatic zebrafish cells using engineered TALENs

(2011) Jeffry D Sander et al.   NATURE BIOTECHNOLOGY

Zebrafish developmental screening of the ToxCast™ Phase I chemical library

(2011) S. Padilla et al.   REPRODUCTIVE TOXICOLOGY

Gold Nanoparticles for Biology and Medicine

(2010) David A. Giljohann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Proactive Approach to Toxic Chemicals: Moving Green Chemistry Beyond Alternatives in the “Safe Chemicals Act of 2010”

(2010) Kira J. M. Matus et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Green Chemistry: Cresting a Summit toward Sustainability

(2010) John L. Tucker   ORGANIC PROCESS RESEARCH & DEVELOPMENT

The Role of Nrf2 and MAPK Pathways in PFOS-Induced Oxidative Stress in Zebrafish Embryos

(2010) Xiongjie Shi et al.   TOXICOLOGICAL SCIENCES

A Predictive Toxicological Paradigm for the Safety Assessment of Nanomaterials

(2009) Huan Meng et al.   ACS Nano

Zebrafish as a correlative and predictive model for assessing biomaterial nanotoxicity

(2009) Valerie E. Fako et al.   ADVANCED DRUG DELIVERY REVIEWS

Toxicity Evaluation for Safe Use of Nanomaterials: Recent Achievements and Technical Challenges

(2009) Saber M. Hussain et al.   ADVANCED MATERIALS

The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research

(2009) Michelle R. Embry et al.   AQUATIC TOXICOLOGY

The inhibition of neuronal calcium ion channels by trace levels of yttrium released from carbon nanotubes

(2009) Lorin M. Jakubek et al.   BIOMATERIALS

The Impact of Toxicity Testing Costs on Nanomaterial Regulation

(2009) Jae-Young Choi et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Transfer of gold nanoparticles from the water column to the estuarine food web

(2009) John L. Ferry et al.   Nature Nanotechnology

Nanoparticle-mediated targeting of MAPK signaling predisposes tumor to chemotherapy

(2009) S. Basu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Zebrafish embryos as models for embryotoxic and teratological effects of chemicals

(2009) Lixin Yang et al.   REPRODUCTIVE TOXICOLOGY

Cellular Uptake and Cytotoxicity of Gold Nanorods: Molecular Origin of Cytotoxicity and Surface Effects

(2009) Alaaldin M. Alkilany et al.   Small

Toxicity Assessments of Multisized Gold and Silver Nanoparticles in Zebrafish Embryos

(2009) Ofek Bar-Ilan et al.   Small

Gold nanoparticles in delivery applications☆

(2008) P GHOSH et al.   ADVANCED DRUG DELIVERY REVIEWS

NANOMATERIALS IN THE ENVIRONMENT: BEHAVIOR, FATE, BIOAVAILABILITY, AND EFFECTS

(2008) Stephen J. Klaine et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Detection of Mercury in Aquatic Environments Using EPRE Reporter Zebrafish

(2008) Brandon W. Kusik et al.   MARINE BIOTECHNOLOGY

Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment

(2008) Robert J. Kavlock et al.   RISK ANALYSIS

Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment

(2008) Daniel Krewski et al.   RISK ANALYSIS

Zinc Finger–Based Knockout Punches for Zebrafish Genes

(2008) Stephen C. Ekker   Zebrafish

Zebrafish Whole-Adult-Organism Chemogenomics for Large-Scale Predictive and Discovery Chemical Biology

(2008) Siew Hong Lam et al.   PLoS Genetics