Liquid Biopsy Promotes Non-Small Cell Lung Cancer Precision Therapy

Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution

(2017) Christopher Abbosh et al.   NATURE

High-throughput screening of rare metabolically active tumor cells in pleural effusion and peripheral blood of lung cancer patients

(2017) Yin Tang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Precision Medicine: From Cancer Screening to Drug Selection and Personalized Immunotherapy

(2017) Xiaolan Deng et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

A Highly Sensitive and Quantitative Test Platform for Detection of NSCLC EGFR Mutations in Urine and Plasma

(2016) Karen L. Reckamp et al.   Journal of Thoracic Oncology

Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease

(2016) Crispin T Hiley et al.   LANCET

Integrated digital error suppression for improved detection of circulating tumor DNA

(2016) Aaron M Newman et al.   NATURE BIOTECHNOLOGY

Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer

(2016) Louise Carter et al.   NATURE MEDICINE

Liquid biopsies for solid tumors: Understanding tumor heterogeneity and real time monitoring of early resistance to targeted therapies

(2016) Angela Esposito et al.   PHARMACOLOGY & THERAPEUTICS

Circulating cell-free DNA has a high degree of specificity to detect exon 19 deletions and the single-point substitution mutation L858R in non-small cell lung cancer

(2016) Xin Qian et al.   Oncotarget

Contribution of KRAS mutations and c.2369C > T (p.T790M) EGFR to acquired resistance to EGFR-TKIs in EGFR mutant NSCLC: a study on circulating tumor DNA

(2016) Marzia Del Re et al.   Oncotarget

Cell-free DNA and next-generation sequencing in the service of personalized medicine for lung cancer

(2016) Catherine W. Bennett et al.   Oncotarget

Evaluation of a novel saliva-based epidermal growth factor receptor mutation detection for lung cancer: A pilot study

(2016) Dan Pu et al.   Thoracic Cancer

Fragment Length of Circulating Tumor DNA

(2016) Hunter R. Underhill et al.   PLoS Genetics

Blood-Based Analysis of Circulating Cell-Free DNA and Tumor Cells for Early Cancer Detection

(2016) Klaus Pantel   PLOS MEDICINE

Effective Capture of Circulating Tumor Cells from a Transgenic Mouse Lung Cancer Model Using Dendrimer Surfaces Immobilized with Anti-EGFR

(2015) Ja Hye Myung et al.   ANALYTICAL CHEMISTRY

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Ex Vivo Culture of CTCs: An Emerging Resource to Guide Cancer Therapy

(2015) S. Maheswaran et al.   CANCER RESEARCH

Bias-Corrected Targeted Next-Generation Sequencing for Rapid, Multiplexed Detection of Actionable Alterations in Cell-Free DNA from Advanced Lung Cancer Patients

(2015) C. P. Paweletz et al.   CLINICAL CANCER RESEARCH

Noninvasive Prenatal Testing by Nanopore Sequencing of Maternal Plasma DNA: Feasibility Assessment

(2015) S. H. Cheng et al.   CLINICAL CHEMISTRY

Rapid Identification of Plasma DNA Samples with Increased ctDNA Levels by a Modified FAST-SeqS Approach

(2015) J. Belic et al.   CLINICAL CHEMISTRY

Predictive and prognostic value of circulating tumor cell detection in lung cancer: A clinician's perspective

(2015) Annette Tognela et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Folate Receptor–Positive Circulating Tumor Cell Detected by LT-PCR–Based Method as a Diagnostic Biomarker for Non–Small-Cell Lung Cancer

(2015) Xiaoxia Chen et al.   Journal of Thoracic Oncology

Detection of tumor-derived DNA in cerebrospinal fluid of patients with primary tumors of the brain and spinal cord

(2015) Yuxuan Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diagnostic yield of targeted next generation sequencing in various cancer types: An information-theoretic approach

(2015) Ian S. Hagemann et al.   Cancer Genetics

Digital PCR analysis of plasma cell-free DNA for non-invasive detection of drug resistance mechanisms in EGFR mutant NSCLC: Correlation with paired tumor samples

(2015) Hidenobu Ishii et al.   Oncotarget

The detection of EpCAM+ and EpCAM– circulating tumor cells

(2015) Sanne de Wit et al.   Scientific Reports

Combined Targeted DNA Sequencing in Non-Small Cell Lung Cancer (NSCLC) Using UNCseq and NGScopy, and RNA Sequencing Using UNCqeR for the Detection of Genetic Aberrations in NSCLC

(2015) Xiaobei Zhao et al.   PLoS One

Efficient Genotyping of KRAS Mutant Non-Small Cell Lung Cancer Using a Multiplexed Droplet Digital PCR Approach

(2015) Alexandra Pender et al.   PLoS One

Noninvasive Saliva-basedEGFRGene Mutation Detection in Patients with Lung Cancer

(2014) Fang Wei et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Second ESMO consensus conference on lung cancer: pathology and molecular biomarkers for non-small-cell lung cancer

(2014) K. M. Kerr et al.   ANNALS OF ONCOLOGY

Noninvasive Detection of Response and Resistance in EGFR-Mutant Lung Cancer Using Quantitative Next-Generation Genotyping of Cell-Free Plasma DNA

(2014) G. R. Oxnard et al.   CLINICAL CANCER RESEARCH

Next-generation sequencing analysis of lung and colon carcinomas reveals a variety of genetic alterations

(2014) SANDY CHEVRIER et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Liquid Biopsies: Genotyping Circulating Tumor DNA

(2014) Luis A. Diaz et al.   JOURNAL OF CLINICAL ONCOLOGY

Circulating tumor DNA as a non-invasive substitute to metastasis biopsy for tumor genotyping and personalized medicine in a prospective trial across all tumor types

(2014) Ronald Lebofsky et al.   Molecular Oncology

Comprehensive molecular profiling of lung adenocarcinoma

(2014) Eric A. Collisson et al.   NATURE

Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer

(2014) Cassandra L Hodgkinson et al.   NATURE MEDICINE

An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage

(2014) Aaron M Newman et al.   NATURE MEDICINE

Molekularpathologie des Lungenkarzinoms

(2014) A. Warth et al.   PATHOLOGE

Detection of Circulating Tumor DNA in Early- and Late-Stage Human Malignancies

(2014) C. Bettegowda et al.   Science Translational Medicine

Isolation and mutational analysis of circulating tumor cells from lung cancer patients with magnetic sifters and biochips

(2013) Christopher M. Earhart et al.   LAB ON A CHIP

Prognostic Impact of Circulating Tumor Cells in Patients with Small Cell Lung Cancer

(2012) Tateaki Naito et al.   Journal of Thoracic Oncology

Comprehensive genomic characterization of squamous cell lung cancers

(2012)   NATURE

Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA

(2012) T. Forshew et al.   Science Translational Medicine

Analysis of Circulating Tumor Cells in Patients with Non-small Cell Lung Cancer Using Epithelial Marker-Dependent and -Independent Approaches

(2011) Matthew G. Krebs et al.   Journal of Thoracic Oncology

Circulating Tumor Cell as a Diagnostic Marker in Primary Lung Cancer

(2009) F. Tanaka et al.   CLINICAL CANCER RESEARCH