Article
Chemistry, Multidisciplinary
Zhaoqing Cai, Huijun Zou, Yirui Chen, Zheng Wang
Summary: In this study, a sample introduction technique based on SCGD of a portable design for ICP-OES was proposed for sensitive determination of mercury. The method achieved a detection limit of 0.22 μg/L, which was significantly lower than traditional pneumatic nebulization. The accuracy and practicality of the method were demonstrated through the analysis of various samples.
CHINESE CHEMICAL LETTERS
(2022)
Review
Chemistry, Multidisciplinary
Xiaoxu Peng, Zheng Wang
Summary: The article provides an overview of the development of solution electrode glow discharge (SEGD) in various fields and discusses its discharge mechanism. SEGD has unique advantages for optical emission spectrometry and mass spectrometry, and it has broad research potential in biology and medicine, material synthesis, electrochemistry, etc.
CHINESE CHEMICAL LETTERS
(2022)
Article
Spectroscopy
Zhaoqing Cai, Zheng Wang
Summary: The use of solution anode glow discharge (SAGD) in hydrogen-helium mixture was evaluated for optical emission spectrometry (OES) of arsenic (As) in solution. The enclosed structure and non-electrode hollow channel were adopted to integrate the functions of vapor generation, atomization, and excitation of As. The study found that propionic acid had the best amplification effect, and the detection limit of SAGD-OES for As was better than that of the fully open-to-air discharge system. SAGD was more susceptible to chemical interferences induced by transition metal elements compared to alkali metals and alkaline earth metals.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2023)
Article
Spectroscopy
Nikola Ivanovic, Nikodin Nedic, Ivan R. Videnovic, Dj. Spasojevic, Nikola Konjevic
Summary: We studied the emission spectra of Ne I 503.775 nm and Ne I 508.038 nm atomic lines in two different DC glow discharge sources. Our modified discharge source allows recording of complex line shapes from two optical directions, enabling spatially resolved Stark polarization spectroscopy. The observed correlation between the electric field strength in the cathode sheath and the recorded spectral shifts provides insights into the cathode sheath parameters.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2023)
Article
Spectroscopy
Jaime Orejas, Nicholas Hazel, Steven J. Ray
Summary: The solution-cathode glow discharge (SCGD) using a novel rectangular-shaped cathode capillary is employed to study aspects of the plasma-liquid interface, with high-speed video and low-angle laser scattering techniques used to evaluate potential mechanisms related to surface-plasma interaction. Frame-by-frame analysis of high-speed video allows estimation of droplet number density, translational speed, and rate of ejection, providing insight into potential analyte transport mechanisms important for analytical atomic spectrometry using SCGD.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2021)
Article
Chemistry, Applied
Krzysztof Greda, Pawel Pohl
Summary: A new method of optical emission spectrometry (OES) using micmplasma source was developed for the determination of Na, K, Mg, Ca, and Zn in wine, without the need for acid digestion. The study also found that red wines have higher levels of K and Mg, and different grape varieties can be distinguished based on the concentrations of K and Ca.
Article
Spectroscopy
Hao Yuan, Xiong-Feng Zhou, Yong Nie, Yao Li, Jian-Ping Liang, De-Zheng Yang, Er-Yan Yan, Wen-Chun Wang, Yong Xu
Summary: Atmospheric pressure electrolyte cathode discharge plasma coupled with temporal resolved atomic emission spectra was used to analyze copper element, optimizing experimental conditions and improving detection sensitivity. Gas temperature and electron density were found to play important roles in the spatiotemporal evolution of discharge and the enhancement of detection sensitivity for elemental analysis.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Monika Gorska, Pawel Pohl
Summary: In this study, novel atmospheric pressure microplasma systems were investigated for the determination of Ga and In by optical emission spectrometry (OES), with optimized working parameters and the addition of low molecular weight organic compounds (LMWOCs) into the solution. The impact of concomitant ions on the signals intensity of Ga and In was also studied, showing the resistance to matrix effects. The detection limits obtained under optimized conditions were comparable to those obtained by large-scale instrumentation, confirming the accuracy and reliability of the developed FLC-APGD-OES method.
Article
Chemistry, Analytical
Zhaoqing Cai, Zhijun Ni, Meng Gao, Zheng Wang
Summary: This study discussed the effects of different salt matrices on the signals of Zn, Cd, Ni, Cu, Cr, and Pb using SCGD-OES. The interference test showed that the levels of interference from sodium, potassium, magnesium, and calcium ions were in the order of Na+ ≈ K+ > Mg2+ ≈ Ca2+. Most elements had inhibited emissions at concentrations exceeding 200 mg L-1 of Na+/K+/Mg2+/Ca2+. The impact of chloride and sulfate ions was not significantly different, and there was almost no interference at 200 mg L-1 of anion content. Spectral interference caused by Na+ and K+ was greater than that of Mg2+ and Ca2+. The role of formic acid (HCOOH) was reassessed and found to have a positive effect on the formation of volatile species such as Pb, regardless of the presence of sodium salts. However, for elements like Cr that are hard to evaporate and stimulate, HCOOH exhibited a strong inhibitory effect, possibly due to exacerbating the deterioration of the excitation state. HCOOH had minor effects on other transition metal elements in the fourth period, such as Zn.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Zhaoqing Cai, Zheng Wang
Summary: In this study, a novel microplasma-assisted vapor generation technique based on solution anode glow discharge (SAGD) was developed as a substitute for the routinely used pneumatic nebulization (PN) in inductively coupled plasma-optical emission spectrometry (ICP-OES). The newly proposed SAGD-ICP-OES system achieved significantly lower detection limits for Cd and Hg compared to conventional PN, as well as good accuracy for multi-element analysis. The system demonstrated its applicability for ultra-trace determination of Cd and Hg through the analysis of certified reference materials and spiked tap water samples.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Peichao Zheng, Yuanjiang Luo, Jinmei Wang, Qiang Hu, Yang Yang, Xuefeng Mao, Chunhong Lai
Summary: A refrigerating anode method was developed to enhance spectral signals and stability in SCGD-AES for the determination of metal elements. Compared to the unrefrigerated system, the detection limits for Ag, Cd, Cu, Mn, and Zn were significantly improved, and the method exhibited high accuracy and reliability in analyzing water samples. The results indicated that SCGD-AES coupled with a refrigerating anode could provide an effective analytical method for on-line determination of metal elements.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2021)
Article
Chemistry, Analytical
Xiang-YU Chen, Zhao-Qing Cai, Yu-Bai Pan, Zheng Wang
Summary: Solution cathode glow discharge atomic emission spectrometry (SCGD-AES) is a low power consumption, small size, and simple operation method for online analysis. However, its limited excitation capacity affects the detection performance of high excitation potential elements such as chromium. In this study, a method for determining chromium content in sewage using SCGD-AES operated in a hydrogen-helium mixed atmosphere was established. The method showed improved detection limits and good repeatability.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2022)
Article
Spectroscopy
Jie Yu, Lijuan Cui, Quanfang Lu, Juanlong Li, Yan Feng, Bo Wang, Xiaojuan Ma
Summary: A novel liquid anode glow discharge (LAGD) system was developed for highly sensitive detection of mercury in water and ore samples. The addition of methanol and formic acid enhanced the signal intensity of mercury and reduced interferences, resulting in a lower detection limit of 4.5 mu g L-1.
SPECTROCHIMICA ACTA PART B-ATOMIC SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Jiadeng Chen, Xiaoming Jiang, Yunfei Tian, Xiandeng Hou
Summary: The harm of heavy metals of microplastics to organisms mainly comes from the part adsorbed on their surface. A new simple in situ preconcentration method, using portable electrolyte atmospheric liquid discharge optical emission spectrometry (ISP-EALD-OES), was proposed for convenient on-site analysis of Cd on microplastics. The microplastic sample was centrifuged with 1% HNO3 to dissolve Cd species from the surface, and the Cd in the supernatant was determined using this method. After optimizing the experimental conditions, the limit of detection (LOD) for Cd was 1.5 ng mL(-1) using the corresponding aqueous standard. This could be a new strategy for field analytical chemistry of trace elements on microplastics' surfaces.
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY
(2023)
Article
Spectroscopy
Xue Li, Chao Wang, Jixin Liu, Xuefei Mao
Summary: In this study, a small platinized tungsten coil (TC) was used in a liquid sampling electrothermal vaporizer (ETV) setup for the first time. A new direct sampling mercury (Hg) analyzer coupled with a dielectric barrier discharge (DBD) and a miniature fiber optic spectrometer (FOS) was developed for sensitive determination of Hg in environmental water. The ETV setup demonstrated a high sample volume and effective sequestering of Hg, with promising accuracy and precision in Hg analysis.
ATOMIC SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Qian Wu, Li Tian, Xiangyu Shan, Huiling Li, Chao Li, Juan Lu
Summary: A novel ECL sensor was developed by modifying Fe3CuO4-Ru(bpy)3+ and GO-CdS@ZnS on the electrode for the detection of permethrin. The sensor exhibited high sensitivity and a wide detection range.
Article
Chemistry, Analytical
Tingting Gong, Lei Liao, Bingying Jiang, Ruo Yuan, Yun Xiang
Summary: In this study, a fluorescent biosensing system for high sensitivity detection of MT was established using a new Ag+-stabilized DNA triplex probe (Ag+-SDTP) combined with catalytic hairpin assembly (CHA) and CRISPR/Cas12a signal enhancements. The sensing method is able to selectively detect MT from other non-specific molecules and can achieve low level detection of MT in diluted human serums, demonstrating its potential for monitoring disease-specific MT biomarker at trace levels.
Article
Chemistry, Analytical
Estrella Sanz Rodriguez, Kyra Wood, Paul R. Haddad, Brett Paull
Summary: This study presents a simple, rapid, and reliable method for determining boron in aqueous solutions using suppressed ion chromatography coupled to electrospray ionisation-triple quadrupole mass spectrometry. The method achieved a low limit of detection and demonstrated excellent analytical performance.
Article
Chemistry, Analytical
Aline Cournut, Paul Moustiez, Yannick Coffinier, Christine Enjalbal, Claudia Bich
Summary: Alzheimer's disease is a major cause of senile dementia and is characterized by the aggregation of neurofibrillary tangles and amyloid plaques in the brain. The A beta 1-42 peptide is considered the primary cause of neurotoxicity due to its insolubility and subsequent aggregation. A beta 1-42 and A beta 1-40 have been identified as relevant biomarkers for AD diagnosis, and SurfaceAssisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) was used to monitor the A beta 1-42/A beta 1-40 ratio without prior sample treatment.
Article
Chemistry, Analytical
Dotse Selali Chormey, Buse Tugba Zaman, Tulay Borahan Kustanto, Sezin Erarpat Bodur, Suleyman Bodur, Elif Ozturk Er, Sezgin Bakirdere
Summary: This review provides an overview of the harmful effects of endocrine disrupting chemicals (EDCs) on human health and introduces the methods for analyzing EDCs. Recent research has focused on using green chemicals, such as deep eutectic solvents (DESs), for microextraction to ensure environmental safety.
Article
Chemistry, Analytical
Yan Zhang, Renfeng Xu, Jingjing Wu, Zhenghong Zhang, Yuhuang Wang, Hongqin Yang, Sheng Zhang
Summary: This study visualized the pore-like structures in prostate cancer cell membranes after treatment with the anticancer drug paclitaxel, demonstrating its mechanism of action related to oxidative damage.
Article
Chemistry, Analytical
Chihong Ma, Qin Zhou, Jinjin Shi, Hua Gao, Di Huang, Huimin Xue, Han Wang, Zhenzhong Zhang, Sen Yang, Junli Zhang, Kaixiang Zhang
Summary: We developed a CRISPR-empowered electrochemical biosensor, named PER-E-CRISPR, for amplification-free and sensitive detection of miR-21. The biosensor combines the advantages of CRISPR/Cas13a and primer exchange reaction (PER) for target amplification. Under optimized conditions, the PER-E-CRISPR assay exhibits a linear range from 10-13 to 10-7 M and a limit of detection of 30.2 fM. The biosensor shows excellent performance in actual plasma, indicating promising prospects for miRNA detection in molecular diagnosis.
Article
Chemistry, Analytical
Gang Liang, Jie Zhao, Yufei Gao, Tao Xie, Jianhui Zhen, Ligang Pan, Wenwen Gong
Summary: Molecular docking (MD) analysis is widely used for studying the interaction between aptamers and small molecules. This study established steady-state aptamers of tertiary structures (SATS) using specific aptamers of tetracycline antibiotics as docking models. Molecular docking results revealed multiple binding sites in the SATS of aptamers, with significant variations in binding free energy (BFE) and docking score (DS). The study also proposed a method for MD analysis based on SATS, providing insights into binding mode and predicting binding sites.
Article
Chemistry, Analytical
Yixuan Xu, Changchang Teng, Huiping Dang, Dalong Yin, Lifeng Yan
Summary: Stable organic radical molecules with high NIR fluorescence quantum efficiency have been synthesized and encapsulated into nanoparticles, which show great potential for both photodynamic therapy (PDT) and photothermal therapy (PTT) of tumors.
Article
Chemistry, Analytical
Yu Su, Dandan Yang, Yanjie Wang, Jie Ding, Lan Ding, Daqian Song
Summary: In this study, a highly selective molecularly imprinted polymer Cu-MIPs@CS was designed and synthesized for bisphenol A (BPA). Cu-MIPs@CS showed significantly enhanced imprinting factor and selective factor towards BPA compared to MIPs@CS. It also exhibited superior discrimination ability between BPA and its structural analogue. Additionally, Cu-MIPs@CS were successfully applied as a solid phase extraction adsorbent for the determination of BPA in drinking water samples.
Article
Chemistry, Analytical
Yi Qiao, Qiongdan Zhang, Yukun He, Tianguang Cheng, Jing Tu
Summary: Single cell heterogeneity plays an important role in many biological phenomena, and distinguishing cells with specific mutations is beneficial for clinical diagnosis and drug screening. This study introduces a gel plate platform that can distinguish cell types based on their phenotypes, with low equipment requirement. The gel platform has potential in point-of-care circumstances and single-cell stimulation responses that prioritize efficiency and simplicity.
Article
Chemistry, Analytical
Chengke Wang, Shuyang Sun, Ping Wang, Huawei Zhao, Wenling Li
Summary: The food safety of aquatic products is a global concern. Nanotechnology-based analyses have advantages in the detection of bacteria, metal ions, and small molecule contaminants. This review summarizes the recent advances in biosensing strategies for aquatic products and highlights the application of nanomaterials, lateral flow-based biosensors, surface-enhanced Raman scattering, microfluidic chips, and molecular imprinting technologies.
Article
Chemistry, Analytical
Liping Zhu, Zeng Tang, Xuemei Zhang, Li Zhu, Tian Meng, Linying Yu, Ting Xiao, Shasha Lu, Xiaoli Xiong, Xiurong Yang
Summary: A sensitive off-on electrochemiluminescence DNA sensor was developed using Exo III-assisted cascade amplification system. The sensor achieved high selectivity and ultra-high sensitivity in detecting target DNA by utilizing ECL and SPR effects. This study provides a new perspective for designing highly sensitive and programmable ECL biosensors.
Article
Chemistry, Analytical
Tong Li, Mengxu Sun, Suping Xia, Ting Huang, Rong-Tian Li, Chunrong Li, Zong Dai, Jin-Xiang Chen, Jun Chen, Nuan Jia
Summary: Here, we developed a binary system based on DNA tetrahedron and fluorogenic RNA aptamers for highly specific and label-free mRNA imaging in living cells. This system achieved high specificity label-free detection of nucleic acids with a detection limit of 1.34 nM. The method has potential applications in early disease diagnosis and new drug development.
Article
Chemistry, Analytical
Yao Zhao, Shu Zhang, Wang Yao, Yuxuan Zhu, Jing Qian, Juan Yang, Nianjun Yang
Summary: A new hierarchical nanostructured composite with high conductivity and catalytic activity is synthesized. The sensor exhibits significant catalytic effect and high sensitivity for monitoring the environmental endocrine disruptor bisphenol A (BPA).
