Sigma-1 receptor chaperones regulate the secretion of brain-derived neurotrophic factor

The sigma-1 receptor enhances brain plasticity and functional recovery after experimental stroke

(2011) Karsten Ruscher et al.   BRAIN

Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders

(2011) Teruo Hayashi et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Sigma Receptor Agonist 2-(4-Morpholinethyl)1 Phenylcyclohexanecarboxylate (Pre084) Increases GDNF and BiP Expression and Promotes Neuroprotection after Root Avulsion Injury

(2011) Clara Penas et al.   JOURNAL OF NEUROTRAUMA

Long-Term Duloxetine Treatment Normalizes Altered Brain-Derived Neurotrophic Factor Expression in Serotonin Transporter Knockout Rats through the Modulation of Specific Neurotrophin Isoforms

(2010) F. Calabrese et al.   MOLECULAR PHARMACOLOGY

Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not

(2010) Vassiliki Nikoletopoulou et al.   NATURE

Role of BDNF and GDNF in drug reward and relapse: A review

(2009) Udi E. Ghitza et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

The pharmacology of sigma-1 receptors

(2009) Tangui Maurice et al.   PHARMACOLOGY & THERAPEUTICS

Targeting sigma receptors: novel medication development for drug abuse and addiction

(2009) Rae R Matsumoto   Expert Review of Clinical Pharmacology

Serum Brain-Derived Neurotrophic Factor, Depression, and Antidepressant Medications: Meta-Analyses and Implications

(2008) Srijan Sen et al.   BIOLOGICAL PSYCHIATRY

Time-dependent biphasic modulation of human BDNF by antidepressants in neuroblastoma cells

(2008) Lorena Donnici et al.   BMC NEUROSCIENCE

A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression

(2008) André Russowsky Brunoni et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

BDNF splice variants from the second promoter cluster support cell survival of differentiated neuroblastoma upon cytotoxic stress

(2008) G. Baj et al.   JOURNAL OF CELL SCIENCE

Altered expression of neurotrophic factors in patients with major depression

(2008) Koji Otsuki et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Chronic treatment with a selective ligand for the sigma-1 receptor chaperone, SA4503, up-regulates BDNF protein levels in the rat hippocampus

(2008) Kazue Kikuchi-Utsumi et al.   NEUROSCIENCE LETTERS