ER proteostasis disturbances in Parkinson's disease: novel insights

α-Synuclein-mediated inhibition of ATF6 processing into COPII vesicles disrupts UPR signaling in Parkinson's disease

(2015) Joel J. Credle et al.   NEUROBIOLOGY OF DISEASE

Control of systemic proteostasis by the nervous system

(2015) Pablo Mardones et al.   TRENDS IN CELL BIOLOGY

Prions: Generation and SpreadVersusNeurotoxicity

(2014) Mark Halliday et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RTCB-1 Mediates Neuroprotection via XBP-1 mRNA Splicing in the Unfolded Protein Response Pathway

(2014) A. Ray et al.   JOURNAL OF NEUROSCIENCE

Disturbance of endoplasmic reticulum proteostasis in neurodegenerative diseases

(2014) Claudio Hetz et al.   NATURE REVIEWS NEUROSCIENCE

Control of dopaminergic neuron survival by the unfolded protein response transcription factor XBP1

(2014) P. Valdes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

When ER stress reaches a dead end

(2013) Hery Urra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Linking membrane dynamics and trafficking to autophagy and the unfolded protein response

(2013) Christelle En Lin Chua et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting the unfolded protein response in disease

(2013) Claudio Hetz et al.   NATURE REVIEWS DRUG DISCOVERY

Identification and Rescue of  -Synuclein Toxicity in Parkinson Patient-Derived Neurons

(2013) C. Y. Chung et al.   SCIENCE

An ERcentric view of Parkinson's disease

(2013) Gabriela Mercado et al.   TRENDS IN MOLECULAR MEDICINE

Parkinson's Disease: Gene Therapies

(2013) P. G. Coune et al.   Cold Spring Harbor Perspectives in Medicine

ER stress inhibits neuronal death by promoting autophagy

(2012) Antoine Fouillet et al.   Autophagy

Hormesis

(2012) Soledad Matus et al.   Autophagy

Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy

(2012) Rene L. Vidal et al.   HUMAN MOLECULAR GENETICS

Endoplasmic Reticulum Stress Is Important for the Manifestations of  -Synucleinopathy In Vivo

(2012) E. Colla et al.   JOURNAL OF NEUROSCIENCE

Glucose Regulated Protein 78 Diminishes α-Synuclein Neurotoxicity in a Rat Model of Parkinson Disease

(2012) Marina S Gorbatyuk et al.   MOLECULAR THERAPY

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

(2012) Claudio Hetz   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Activation of the unfolded protein response enhances motor recovery after spinal cord injury

(2012) V Valenzuela et al.   Cell Death & Disease

A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease

(2011) Alexander Zimprich et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The Endoplasmic Reticulum Stress Sensor, ATF6α, Protects against Neurotoxin-induced Dopaminergic Neuronal Death

(2010) Naohiro Egawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

(2009) C. Hetz et al.   GENES & DEVELOPMENT

Protective effect against Parkinson's disease-related insults through the activation of XBP1

(2008) Megumi Sado et al.   BRAIN RESEARCH