New insights into the role of Runx1 in epithelial stem cell biology and pathology

A systems biology approach to the global analysis of transcription factors in colorectal cancer

(2012) Meeta P Pradhan et al.   BMC CANCER

Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer

(2012) Cornelia Johanna Franziska Scheitz et al.   EMBO JOURNAL

Multiple phosphorylation sites are important for RUNX1 activity in early hematopoiesis and T-cell differentiation

(2012) Mayumi Yoshimi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Sequence analysis of mutations and translocations across breast cancer subtypes

(2012) Shantanu Banerji et al.   NATURE

Hairy tale of signaling in hair follicle development and cycling

(2012) Jayhun Lee et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Wnt Signaling in Cancer

(2012) P. Polakis   Cold Spring Harbor Perspectives in Biology

The Role of Pea3 Group Transcription Factors in Esophageal Squamous Cell Carcinoma

(2011) Hiu-Fung Yuen et al.   AMERICAN JOURNAL OF PATHOLOGY

The role of the PD-1 pathway in autoimmunity and peripheral tolerance

(2011) Brian T. Fife et al.   Annals of the New York Academy of Sciences

Runx1 is a tumor suppressor gene in the mouse gastrointestinal tract

(2011) Remond J. A. Fijneman et al.   CANCER SCIENCE

Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments

(2011) Karen M. Osorio et al.   JOURNAL OF CELL BIOLOGY

Identifying the cellular origin of squamous skin tumors

(2011) G. Lapouge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intersection of FOXO- and RUNX1-mediated gene expression programs in single breast epithelial cells during morphogenesis and tumor progression

(2011) L. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defining the origins of Ras/p53-mediated squamous cell carcinoma

(2011) A. C. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical significance of runt-related transcription factor 1 polymorphism in prostate cancer

(2010) Shu-Pin Huang et al.   BJU INTERNATIONAL

Associations between genetic variation in RUNX1 , RUNX2 , RUNX3 , MAPK1 and eIF4E and risk of colon and rectal cancer: additional support for a TGF-β-signaling pathway

(2010) Martha L. Slattery et al.   CARCINOGENESIS

Runx1 isoforms show differential expression patterns during hematopoietic development but have similar functional effects in adult hematopoietic stem cells

(2010) Grant A. Challen et al.   EXPERIMENTAL HEMATOLOGY

Matrix metalloproteinase-2 and matrix metalloproteinase-9 codistribute with transcription factors RUNX1/AML1 and ETV5/ERM at the invasive front of endometrial and ovarian carcinoma☆

(2010) Jesús Planagumà et al.   HUMAN PATHOLOGY

Runx1 Directly Promotes Proliferation of Hair Follicle Stem Cells and Epithelial Tumor Formation in Mouse Skin

(2010) C. S. L. Hoi et al.   MOLECULAR AND CELLULAR BIOLOGY

In vitroandin vivoeffects on neural crest stem cell differentiation by conditional activation of Runx1 short isoform and its effect on neuropathic pain behavior

(2010) Nadezda Kanaykina et al.   UPSALA JOURNAL OF MEDICAL SCIENCES

Identifying significant genetic regulatory networks in the prostate cancer from microarray data based on transcription factor analysis and conditional independency

(2009) Hsiang-Yuan Yeh et al.   BMC Medical Genomics

Distinct Self-Renewal and Differentiation Phases in the Niche of Infrequently Dividing Hair Follicle Stem Cells

(2009) Ying V. Zhang et al.   Cell Stem Cell

The Hair Follicle as a Dynamic Miniorgan

(2009) Marlon R. Schneider et al.   CURRENT BIOLOGY

Cell cycle and developmental control of hematopoiesis by Runx1

(2009) Alan D. Friedman   JOURNAL OF CELLULAR PHYSIOLOGY

Runx1 is required for the endothelial to haematopoietic cell transition but not thereafter

(2009) Michael J. Chen et al.   NATURE

Runx1 modulates developmental, but not injury-driven, hair follicle stem cell activation

(2008) K. M. Osorio et al.   DEVELOPMENT

Quantitative proliferation dynamics and random chromosome segregation of hair follicle stem cells

(2008) Sanjeev K Waghmare et al.   EMBO JOURNAL

A chromatin immunoprecipitation screen in mouse keratinocytes reveals Runx1 as a direct transcriptional target of ΔNp63

(2008) Kori Ortt et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Crypt stem cells as the cells-of-origin of intestinal cancer

(2008) Nick Barker et al.   NATURE