miR-335 Correlates with Senescence/Aging in Human Mesenchymal Stem Cells and Inhibits Their Therapeutic Actions Through Inhibition of AP-1 Activity

Mitochondrial oxidative stress caused by Sod2 deficiency promotes cellular senescence and aging phenotypes in the skin

(2016) Michael C. Velarde et al.   Aging-US

Cellular senescence involves an intracrine prostaglandin E2 pathway in human fibroblasts

(2013) Sébastien Martien et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

SRF selectively controls tip cell invasive behavior in angiogenesis

(2013) C. A. Franco et al.   DEVELOPMENT

CXCL12/CXCR4 axis promotes mesenchymal stem cell mobilization to burn wounds and contributes to wound repair

(2013) Changjiang Hu et al.   JOURNAL OF SURGICAL RESEARCH

Metastasis Suppressor microRNA-335 Targets the Formin Family of Actin Nucleators

(2013) Jennifer Lynch et al.   PLoS One

An Oct4-pRb Axis, Controlled by MiR-335, Integrates Stem Cell Self-Renewal and Cell Cycle Control

(2013) Stefan Schoeftner et al.   STEM CELLS

Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy

(2013) J C Estrada et al.   Cell Death & Disease

Rapid protein kinase D1 signaling promotes migration of intestinal epithelial cells

(2012) Steven H. Young et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mesenchymal stem cells as therapeutic agents of inflammatory and autoimmune diseases

(2012) Olga DelaRosa et al.   CURRENT OPINION IN BIOTECHNOLOGY

Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer

(2012) Bruno Bernardes de Jesus et al.   EMBO Molecular Medicine

Adipose-derived mesenchymal stromal cells induce immunomodulatory macrophages which protect from experimental colitis and sepsis

(2012) Per Anderson et al.   GUT

Age-related alterations in mesenchymal stem cells related to shift in differentiation from osteogenic to adipogenic potential: Implication to age-associated bone diseases and defects

(2012) MiJung Kim et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Lamin B1 loss is a senescence-associated biomarker

(2012) Adam Freund et al.   MOLECULAR BIOLOGY OF THE CELL

Macrophage-Associated Mesenchymal Stem Cells Assume an Activated, Migratory, Pro-Inflammatory Phenotype with Increased IL-6 and CXCL10 Secretion

(2012) Kevin Anton et al.   PLoS One

Nuclear Morphometric Analysis (NMA): Screening of Senescence, Apoptosis and Nuclear Irregularities

(2012) Eduardo C. Filippi-Chiela et al.   PLoS One

Culture of human mesenchymal stem cells at low oxygen tension improves growth and genetic stability by activating glycolysis

(2011) J C Estrada et al.   CELL DEATH AND DIFFERENTIATION

PKD is a kinase of Vps34 that mediates ROS-induced autophagy downstream of DAPk

(2011) A Eisenberg-Lerner et al.   CELL DEATH AND DIFFERENTIATION

Tumor Suppressor and Aging Biomarker p16INK4aInduces Cellular Senescence without the Associated Inflammatory Secretory Phenotype

(2011) Jean-Philippe Coppé et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Age-related changes in skeletal muscle reactive oxygen species generation and adaptive responses to reactive oxygen species

(2011) Malcolm J. Jackson et al.   JOURNAL OF PHYSIOLOGY-LONDON

miR-335 and miR-34a Promote Renal Senescence by Suppressing Mitochondrial Antioxidative Enzymes

(2011) X.-Y. Bai et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

MicroRNA profiling reveals age-dependent differential expression of nuclear factor κB and mitogen-activated protein kinase in adipose and bone marrow-derived human mesenchymal stem cells

(2011) Amitabh C Pandey et al.   Stem Cell Research & Therapy

Reduction of Nup107 attenuates the growth factor signaling in the senescent cells

(2010) Sung Young Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

miR-335 orchestrates cell proliferation, migration and differentiation in human mesenchymal stem cells

(2010) M Tomé et al.   CELL DEATH AND DIFFERENTIATION

Prostaglandin E2 plays a key role in the immunosuppressive properties of adipose and bone marrow tissue-derived mesenchymal stromal cells

(2010) Rosa Yañez et al.   EXPERIMENTAL CELL RESEARCH

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

(2010) Mariela Jaskelioff et al.   NATURE

A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen

(2010) Jean-Philippe Coppé et al.   PLoS One

Mesenchymal Stromal Cells

(2009) Maria Ester Bernardo et al.   Annals of the New York Academy of Sciences

Human adipose-derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in rheumatoid arthritis

(2009) E Gonzalez-Rey et al.   ANNALS OF THE RHEUMATIC DISEASES

A study of microRNAsin silicoandin vivo: emerging regulators of embryonic stem cells

(2009) Kye-Seong Kim et al.   FEBS Journal

Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis

(2009) E Gonzalez-Rey et al.   GUT

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion

(2009) Francis Rodier et al.   NATURE CELL BIOLOGY

‘When an old rat smells a cat’: A decline in defense-related, but not accessory olfactory, Fos expression in aged rats

(2009) Glenn E. Hunt et al.   NEUROBIOLOGY OF AGING

An RNAi Screen of Chromatin Proteins Identifies Tip60-p400 as a Regulator of Embryonic Stem Cell Identity

(2008) Thomas G. Fazzio et al.   CELL

Gene and microRNA expression signatures of human mesenchymal stromal cells in comparison to fibroblasts

(2008) Sohyun Bae et al.   CELL AND TISSUE RESEARCH

Adipose-Derived Mesenchymal Stem Cells Alleviate Experimental Colitis by Inhibiting Inflammatory and Autoimmune Responses

(2008) Manuel A. González et al.   GASTROENTEROLOGY

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner

(2008) So Ra Kim et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE

Premature Aging in Skeletal Muscle Lacking Serum Response Factor

(2008) Charlotte Lahoute et al.   PLoS One

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY

Age-related changes in human bone marrow-derived mesenchymal stem cells: Consequences for cell therapies

(2007) A. Stolzing et al.   MECHANISMS OF AGEING AND DEVELOPMENT