Review
Biochemistry & Molecular Biology
Lucia Pazderova, Ece Zeynep Tuzun, Dmytro Bavol, Miroslava Litecka, Lukas Fojt, Bohumir Gruner
Summary: The cobalt bis(dicarbollide)(1(-)) anion plays a significant role in material science and medicine due to its unique properties and the availability of synthetic routes for easy modifications. The modification of the dicarbollide cage has been well-established for boron atom substitutions, but there has been limited progress on carbon vertex modifications. Recent developments in metalation reactions on C-H vertices have enabled direct and straightforward cage modifications, leading to new trends in the field. This review provides an overview of these methods and their applications in designing unconventional drugs.
Article
Chemistry, Multidisciplinary
I. B. Sivaev, I. D. Kosenko
Summary: The study using H-1 NMR revealed that the transoid conformation of dihalogenated derivatives of cobalt bis(dicarbollide) [8,8 '-X-2-3,3 '-Co(1,2-C2B9H10)(2)](-) (X = Cl, Br, I), stabilized by intramolecular C-H... X hydrogen bonds between ligands, is maintained in solution.
RUSSIAN CHEMICAL BULLETIN
(2021)
Article
Chemistry, Analytical
Tatiana Shishkanova, Alla Sinica
Summary: A cobalt bis(dicarbollide) derivative deposited onto the surface of a graphite electrode through an electrochemically oxidized o-phenylenediamine unit (pCB-oPD) is proposed for the detection of catecholamine metabolites, namely homovanillic acid (HVA) and vanillylmandelic acid (VMA). The set of electrochemical techniques makes it possible to evaluate the options of the individual and simultaneous detection of metabolites.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Cyrille Galven, Valerie Albin, Simon Hubert, Virginie Lair, Armelle Ringuede, Marie-Pierre Crosnier-Lopez, Francoise Le Berre
Summary: Two new acentric oxycarbonates Na6Li4MO4(CO3)(4) (M = W and Mo) with promising potential as electrolytes for electrochemical devices were successfully synthesized. The crystal structures of Na6Li4MO4(CO3)(4) (M = W and Mo) were determined to be acentric cubic P-43m space group. The conductivity of both solid and molten phases showed purely ionic behavior and was comparable to classical molten alkali electrolytes.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
I. P. Studenyak, A. I. Pogodin, M. J. Filep, O. I. Symkanych, T. Y. Babuka, O. P. Kokhan, P. Kus
Summary: High-quality single crystals of Ag6+x(P1-xGex)S5I solid solutions were grown by vertical zone crystallization method. The crystal structure and ion transport mechanism were studied using XRD analysis and impedance spectroscopy, showing the peculiarities and maxima of the ionic component in the solid solutions.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Biochemistry & Molecular Biology
Lyubov G. Dezhenkova, Anna A. Druzina, Yulia L. Volodina, Nadezhda Dudarova, Natalia A. Nekrasova, Olga B. Zhidkova, Mikhail A. Grin, Vladimir Bregadze
Summary: Novel cobalt bis(dicarbollide)-curcumin conjugates were synthesized and found to be non-cytotoxic against tumor and normal cells. Flow cytometry analysis showed that these conjugates entered the cells in a time-dependent manner.
Article
Biochemistry & Molecular Biology
Ekaterina Bogdanova, Marina Yu Stogniy, Kyrill Yu Suponitsky, Igor B. Sivaev, Vladimir Bregadze
Summary: A series of novel cobalt bis(dicarbollide) based amidines were synthesized by adding primary and secondary amines to a specific compound, leading to different isomer mixtures when reacting with primary vs. secondary amines. Crystal structures of these compounds were determined by X-ray diffraction.
Article
Chemistry, Physical
Mahesh K. Pallikonda, Taysir H. Nayfeh
Summary: While CNTs show potential for ultra-conductivity in copper matrix, scaling up production remains a challenge due to limited effective methods and resulting in attenuation of wire cross-section.
Article
Biochemistry & Molecular Biology
Krzysztof Smialkowski, Carla Sardo, Zbigniew J. J. Lesnikowski
Summary: The exploitation of metallacarboranes' potential in various fields requires convenient and versatile methods for their functionalization. This study reports the functionalization of cobalt bis(1,2-dicarbollide) at 8,8 '-boron atoms with different heterobifunctional moieties. It also describes an approach to the synthesis of three and four functionalized metallacarboranes simultaneously at boron and carbon atoms.
Article
Crystallography
Denis M. Chudak, Olga N. Kazheva, Irina D. Kosenko, Gennady Shilov, Igor B. Sivaev, Georgy G. Abashev, Elena Shklyaeva, Lev Buravov, Dmitry N. Pevtsov, Tatiana N. Starodub, Vladimir Bregadze, Oleg A. Dyachenko
Summary: New radical-cation salts based on TMTTF and TMsTSF with different metallacarborane anions were synthesized, with the third salt being a narrow-gap semiconductor.
Article
Chemistry, Multidisciplinary
Naoya Kinoshita, Takashi Shirahata, Toshio Naito, Yohji Misaki
Summary: Synthesis and X-ray structure analysis of TSF-based donors substituted with the meso-dimethylethylenedithio group were successfully performed. The donor molecules in (meso-DM-BETS)(2)X formed a dimerized face-to-face p-stack, with a packing pattern classified as ss-type. Tight-binding band calculation suggested that the meso-DM-BETS salts have a two-dimensional Fermi surface and wide bandwidth. Both salts exhibited metallic conductivities down to low temperatures with sigma(r.t.) = 45-46 S cm(-1).
BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN
(2023)
Article
Chemistry, Inorganic & Nuclear
Nabil Mroweh, Alexandra Bogdan, Flavia Pop, Pascale Auban-Senzier, Nicolas Vanthuyne, Elsa B. Lopes, Manuel Almeida, Narcis Avarvari
Summary: This study presents the preparation and structural characterization of a series of radical cation salts, investigating the impact of stereogenic centers, counter-ion nature, and electrocrystallization conditions on the crystal structures and conducting properties of the materials. Single crystal resistivity measurements show quasi-metallic conductivity for certain salts, while semiconducting behavior is observed for others.
Article
Chemistry, Inorganic & Nuclear
Hadi Hachem, HengBo Cui, Reizo Kato, Pere Alemany, Enric Canadell, Olivier Jeannin, Marc Fourmigue, Dominique Lorcy
Summary: Highly conducting, mixed-valence, multi-component nickel bis-(diselenolene) salts were obtained by electrocrystallization. Depending on the counter ion used, the salts showed different stoichiometries of 1:2 and 1:3. This is a rare example of mixed-valence conducting salts of nickel diselenolene complexes, which usually form single component neutral species. The transport measurements under high pressure and band structure calculations confirmed the semiconducting and quasi metallic characters of the salts.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Sherly Novia Sari, Pawel Nieroda, Pawel Pasierb
Summary: The poor chemical stability and unsatisfactory electrical conductivity of BaCeO3-based protonic conductors can be improved by doping, forming solid solutions, or creating composite materials. This study focuses on the development of BaCe0.9Y0.1O3 - (Ba-Ce-Y-Si-P-O) composites using the latter approach. The sintering method and the presence of a modifier phase were found to significantly affect the phase composition, crystallographic structure, microstructure, and electrical properties, with only a minor increase in electrical conductivity observed in samples sintered using the Spark Plasma Sintering method.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Chemistry, Multidisciplinary
C. Marino, J. Basbus, A. L. Larralde, J. A. Alonso, M. T. Fernandez-Diaz, L. Troncoso
Summary: The study focused on the structural characterization of LaSrGa1-xMgxO4-delta oxides, potential electrolytes for solid oxide fuel cells. Results showed that the presence of Mg in the structure promoted non-stoichiometry of oxygen vacancies, improving ionic conduction properties significantly. Neutron powder diffraction, combined with electrical characterization, provided insights into the pathways and mechanisms of oxygen ion diffusion within the crystalline structure.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Biochemistry & Molecular Biology
Kyrill Yu. Suponitsky, Sergey A. A. Anufriev, Igor B. B. Sivaev
Summary: The crystal structures of two isomeric triiodo derivatives of ortho-carborane were determined, showing different bonding patterns of iodine atoms with the carborane cage. The existence of dihalogen bonds and halogen bonds were observed in the structures. Comparison with the brominated derivative revealed similarities and differences in the bonding interactions.
Review
Chemistry, Inorganic & Nuclear
Marina Yu. Stogniy, Sergey A. Anufriev, Igor B. Sivaev
Summary: This review summarizes data on the main types of charge-compensated nido-carborane derivatives, which have increased stability compared to organic analogs. The stability is attributed to the stabilizing electron-donor action of the boron cage. The charge-compensated derivatives are discussed based on the type of heteroatom bonded to a boron atom.
Article
Chemistry, Inorganic & Nuclear
Igor B. Sivaev, Sergey A. Anufriev, Akim V. Shmalko
Summary: Based on the data of 1H NMR spectra, the effect of various substituents at boron atoms in different positions of the ortho-carborane cage on its CH-acidity and the electron-withdrawing effect upon substitution at the carbon atom is discussed. It is found that the introduction of chlorine atoms slightly reduces the CH-acidity, whereas the introduction of bromine and iodine atoms significantly increases the CH-acidity compared to the parent orthocarborane. The introduction of halogen atoms to the boron atoms bound to both carbon atoms leads to a significant increase in the CH-acidity, regardless of halogen electronegativity. However, in the case of polychlorinated derivatives of ortho-carborane, the total effect of the substituent covers the decrease in CH-acidity when the first halogen atoms are introduced into specific positions. The introduction of alkyl substituents reduces the CH-acidity, while the introduction of aryl substituents has the opposite effect.
INORGANICA CHIMICA ACTA
(2023)
Article
Chemistry, Inorganic & Nuclear
Dmitriy K. Semyonov, Georgii K. Slushko, Marina Yu. Stogniy, Sergey A. Anufriev, Ivan A. Godovikov, Kyrill Yu. Suponitsky, Vladimir I. Bregadze, Igor B. Sivaev
Summary: The reactions of nickel(II) phosphine complexes [(dppe)NiCl2], [(MePh2P)2NiCl2] and [(Ph3P)2NiCl2] with C-substituted nido-carboranes [7-R-nido-7,8-C2B9H11]- were investigated. Different reactions were observed depending on the specific combination of reactants. Overall, the findings highlight the impact of steric interactions on the formation of nickelacarboranes.
Article
Chemistry, Multidisciplinary
K. E. Erdelyi, A. A. Antonets, O. B. Zhidkova, A. A. Druzina, A. A. Nazarov, S. V. Timofeev, I. B. Sivaev, V. I. Bregadze
Summary: Boron-containing conjugates of cholesterol were synthesized via copper(I)-catalyzed 1,3-dipolar [3+2] cycloaddition reactions. The antiproliferative activity of the conjugates was evaluated against various human cell lines, showing low toxicity and potential for cancer treatment.
RUSSIAN CHEMICAL BULLETIN
(2023)
Article
Chemistry, Inorganic & Nuclear
Dmitriy K. Semyonov, Marina Yu. Stogniy, Kyrill Yu. Suponitsky, Igor B. Sivaev
Summary: New carboranyl thioethers were synthesized using the alkylation of the trimethylammonium salt of 1-mercapto-ortho-carborane with 1-bromo-2-methoxyethane and 1-bromo-3-methoxypropane. The deboronation of these thioethers with cesium fluoride yielded the corresponding nido-carboranes. The reactions of the nido-carboranes with various nickel(II) phosphine complexes resulted in the synthesis of nickelacarboranes.
Review
Chemistry, Multidisciplinary
Igor B. B. Sivaev
Summary: This review aims to compile the literature data on the synthesis and properties of icosahedral carborane derivatives, specifically focusing on the attachment of exo-polyhedral three- and four-coordinated boron substituents directly to the carborane cage through boron-carbon or boron-boron bonds. Various classes of compounds including carboranyl aryl boranes, boronic acids and their derivatives, boroles, diazaboroles, etc., are discussed. The review particularly highlights carborane-fused heterocycles containing boron atoms.
CHEMISTRY-SWITZERLAND
(2023)
Article
Chemistry, Inorganic & Nuclear
Varvara V. Avdeeva, Alexey S. Kubasov, Alexey V. Golubev, Sergey A. Anufriev, Igor B. Sivaev, Svetlana E. Nikiforova, Lyudmila V. Goeva, Elena A. Malinina, Nikolay T. Kuznetsov
Summary: Reactions of [B11H11]2- with copper(I) and silver(I) complexes [(Ph3P)3MX] (M = Cu, X = Cl; M = Ag, X = NO3) led to the formation of metallaboranes (Bu4N)3[commo-M(B11H11)2] instead of M-H-B complexes. The crystal structure of (Bu4N)3[Ag(B11H11)2] was determined using single-crystal X-ray diffraction. Hirschfeld surface analysis and DFT calculations were conducted for both metallaboranes [M (B11H11)2]3- (M = Cu, Ag).
INORGANICA CHIMICA ACTA
(2023)
Article
Biochemistry & Molecular Biology
Dmitriy K. Semyonov, Marina Yu. Stogniy, Sergey A. Anufriev, Sergey V. Timofeev, Kyrill Yu. Suponitsky, Igor B. Sivaev
Summary: A series of C- and B-substituted nido-carborane derivatives with a pendant pyridyl group were synthesized and used as ligands for the complexation reactions with nickel(II) and palladium(II) chlorides, forming six new metallacomplexes. The structures of these complexes were determined using single crystal X-ray diffraction.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Medicine, Research & Experimental
Satoshi Okada, Kai Nishimura, Qarri Ainaya, Kouichi Shiraishi, Sergey A. Anufriev, Igor B. Sivaev, Yoshinori Sakurai, Minoru Suzuki, Masayuki Yokoyama, Hiroyuki Nakamura
Summary: In this study, a gadolinium-boron-conjugated albumin (Gd-MID-BSA) was developed for MRI-guided neutron capture therapy. The accumulation of Gd-MID-BSA in tumors was confirmed by MRI and biodistribution analysis. The concentration ratios of boron and gadolinium in tumors satisfied the requirements for boron neutron capture therapy (BNCT) and gadolinium neutron capture therapy (GdNCT). The conjugation of gadolinium and boron in the albumin molecule enhanced the therapeutic effect of BNCT and showed potential as a promising treatment for malignant tumors.
MOLECULAR PHARMACEUTICS
(2023)
Article
Biochemistry & Molecular Biology
Anna A. Druzina, Nadezhda V. Dudarova, Ivan V. Ananyev, Anastasia A. Antonets, Dmitry N. Kaluzhny, Alexey A. Nazarov, Igor B. Sivaev, Vladimir I. Bregadze
Summary: The synthesis of the first conjugates of acridine with cobalt bis(dicarbollide) was reported. A novel 9-azido derivative of acridine was prepared and its solid-state molecular structure was determined. The obtained conjugates showed weak binding with DNA, but demonstrated potential for the development of new agents for boron neutron capture therapy (BNCT).
Article
Chemistry, Multidisciplinary
A. A. Druzina, N. V. Dudarova, I. B. Sivaev, V. I. Bregadze
Summary: A new azidoethylaminoacridine compound was synthesized and boron-containing acridine conjugates were obtained through a specific reaction. These compounds have potential applications as DNA intercalators for boron neutron capture therapy.
RUSSIAN CHEMICAL BULLETIN
(2023)
Article
Chemistry, Inorganic & Nuclear
A. M. Zimina, T. V. Kolpakova, S. A. Anufriev, E. I. Zueva, N. V. Somov, I. B. Sivaev, I. D. Grishin
Summary: The reaction of 9-iodo-ortho-carborane with n-butylmagnesium bromide produces 9-n-butyl-ortho-carborane. Further reaction of this compound with alkali in boiling ethanol yields a new nido-carborane [5-Bu-7,8-C2B9H11](-) (I) with a n-butyl substituent. Subsequent reaction of compound I with RuCl2(PPh3)(Ph2P(CH2)(4)PPh2) leads to the formation of a ruthenium(IV) closo complex 3,3-(Ph2P(CH2)(4)PPh2)-3-H-3-Cl-9-Bu-closo-3,1,2-RuC2B9H10 (II) characterized by 2D NMR spectroscopy. Heating compound II with carbon tetrachloride results in the formation of the 17-electron complex 3,3-(Ph2P(CH2)(4)PPh2)-3-Cl-9-Bu-closo-3,1,2-RuC2B9H10, and the structure of this complex is determined using X-ray diffraction.
RUSSIAN JOURNAL OF COORDINATION CHEMISTRY
(2023)
Review
Chemistry, Inorganic & Nuclear
Yu. N. Las'kova, A. A. Serdyukov, I. B. Sivaev
Summary: This article summarizes the synthesis methods, properties, and application fields of various boron-containing coumarin derivatives, with particular emphasis on derivatives with various polyhedral boron clusters as substituents, such as carboranes, metallacarboranes, and the closo-dodecaborate anion. Derivatives of coumarin with simple organoboron compounds, boronic acids and their esters, are also considered.
RUSSIAN JOURNAL OF INORGANIC CHEMISTRY
(2023)
Review
Chemistry, Physical
Varvara V. Avdeeva, Svetlana E. Nikiforova, Elena A. Malinina, Igor B. Sivaev, Nikolay T. Kuznetsov
Summary: In this article, composites and materials prepared from boron hydride cluster compounds are presented. The utilization of these materials as boron protective coatings, as well as their applications in synthesizing boron carbide, boron nitride, metal borides, metal-containing composites, and neutron shielding materials, are discussed.
Article
Chemistry, Inorganic & Nuclear
Mahsa Saberian, Alireza Nezamzadeh-Ejhieh
Summary: CuO was successfully supported on clinoptilolite nanoparticles (NCP) via ion exchange and calcination, forming CuO-NCP photocatalysts. CuO-NCP exhibited enhanced photocatalytic activity towards tetracycline (TC), and the best degradation performance was achieved under optimal conditions (25 ppm TC solution, pH 4.8, and 0.5 g/L catalyst).
SOLID STATE SCIENCES
(2024)