Long-Term Effects of Nanoparticles on Nutrition and Metabolism

Role for nanomaterial-autophagy interaction in neurodegenerative disease

(2014) Stephan T. Stern et al.   Autophagy

LDLR-mediated peptide-22-conjugated nanoparticles for dual-targeting therapy of brain glioma

(2013) Bo Zhang et al.   BIOMATERIALS

Biodegradable self-assembled nanoparticles of poly (d,l-lactide-co-glycolide)/hyaluronic acid block copolymers for target delivery of docetaxel to breast cancer

(2013) Jingbin Huang et al.   BIOMATERIALS

Intracellular trafficking and cellular uptake mechanism of mPEG-PLGA-PLL and mPEG-PLGA-PLL-Gal nanoparticles for targeted delivery to hepatomas

(2013) Peifeng Liu et al.   BIOMATERIALS

Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy

(2013) Joungmok Kim et al.   CELL

Nile Blue-Based Nanosized pH Sensors for Simultaneous Far-Red and Near-Infrared Live Bioimaging

(2013) Jeppe Madsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gold nanoparticles induce transcriptional activity of NF-κB in a B-lymphocyte cell line

(2013) Monita Sharma et al.   Nanoscale

Mechanism of Silver Nanoparticles Action on Insect Pigmentation Reveals Intervention of Copper Homeostasis

(2013) Najealicka Armstrong et al.   PLoS One

Titanium dioxide nanoparticles increase inflammatory responses in vascular endothelial cells

(2013) Sung Gu Han et al.   TOXICOLOGY

Single-walled carbon nanotubes and graphene oxides induce autophagosome accumulation and lysosome impairment in primarily cultured murine peritoneal macrophages

(2013) Bin Wan et al.   TOXICOLOGY LETTERS

Autophagy-Sensitized Cytotoxicity of Quantum Dots in PC12 Cells

(2013) Xiaoming Li et al.   Advanced Healthcare Materials

Dual Enzyme-like Activities of Iron Oxide Nanoparticles and Their Implication for Diminishing Cytotoxicity

(2012) Zhongwen Chen et al.   ACS Nano

Autophagy as a Stress-Response and Quality-Control Mechanism: Implications for Cell Injury and Human Disease

(2012) Lyndsay Murrow et al.   Annual Review of Pathology-Mechanisms of Disease

Cellular internalization and stress response of ingested amorphous silica nanoparticles in the midgut of Drosophila melanogaster

(2012) Ashutosh Pandey et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The prolongation of the lifespan of rats by repeated oral administration of [60]fullerene

(2012) Tarek Baati et al.   BIOMATERIALS

TPC Proteins Are Phosphoinositide- Activated Sodium-Selective Ion Channels in Endosomes and Lysosomes

(2012) Xiang Wang et al.   CELL

Ovarian dysfunction and gene-expressed characteristics of female mice caused by long-term exposure to titanium dioxide nanoparticles

(2012) Guodong Gao et al.   JOURNAL OF HAZARDOUS MATERIALS

Fullerol antagonizes dexamethasone-induced oxidative stress and adipogenesis while enhancing osteogenesis in a cloned bone marrow mesenchymal stem cell

(2012) Hongjian Liu et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Enhancement of lipopolysaccharide-induced nitric oxide and interleukin-6 production by PEGylated gold nanoparticles in RAW264.7 cells

(2012) Zhimin Liu et al.   Nanoscale

Copper(ii) oxide nanoparticles penetrate into HepG2 cells, exert cytotoxicity via oxidative stress and induce pro-inflammatory response

(2012) Jean-Pascal Piret et al.   Nanoscale

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

(2012) Congcong He et al.   NATURE

Food Chain Transport of Nanoparticles Affects Behaviour and Fat Metabolism in Fish

(2012) Tommy Cedervall et al.   PLoS One

Concentration-Dependent, Size-Independent Toxicity of Citrate Capped AuNPs in Drosophila melanogaster

(2012) Giuseppe Vecchio et al.   PLoS One

Organically Modified Silica Nanoparticles Are Biocompatible and Can Be Targeted to Neurons In Vivo

(2012) Farda Barandeh et al.   PLoS One

Excessive Sodium Ions Delivered into Cells by Nanodiamonds: Implications for Tumor Therapy

(2012) Ying Zhu et al.   Small

Gold Nanoparticles Induce Autophagosome Accumulation through Size-Dependent Nanoparticle Uptake and Lysosome Impairment

(2011) Xiaowei Ma et al.   ACS Nano

Sensing of energy and nutrients by AMP-activated protein kinase

(2011) D Grahame Hardie   AMERICAN JOURNAL OF CLINICAL NUTRITION

The inhibition of death receptor mediated apoptosis through lysosome stabilization following internalization of carboxyfullerene nanoparticles

(2011) Wei Li et al.   BIOMATERIALS

Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles

(2011) Mohd Imran Khan et al.   BIOMATERIALS

Cytotoxicity and Genotoxicity of Size-Fractionated Iron Oxide (Magnetite) in A549 Human Lung Epithelial Cells: Role of ROS, JNK, and NF-κB

(2011) Mathias Könczöl et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Understanding and controlling the interaction of nanomaterials with proteins in a physiological environment

(2011) Carl D. Walkey et al.   CHEMICAL SOCIETY REVIEWS

Differential toxicity of silver and titanium dioxide nanoparticles on Drosophila melanogaster development, reproductive effort, and viability: Size, coatings and antioxidants matter

(2011) Ryan Posgai et al.   CHEMOSPHERE

Chronic exposure to nanosized, anatase titanium dioxide is not cyto- or genotoxic to Chinese hamster ovary cells

(2011) Shuguang Wang et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Acute and Chronic Toxicity Effects of Silver Nanoparticles (NPs) onDrosophila melanogaster

(2011) Ales Panacek et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Tissue distribution and histopathological effects of titanium dioxide nanoparticles after intravenous or subcutaneous injection in mice

(2011) T. H. Umbreit et al.   JOURNAL OF APPLIED TOXICOLOGY

Size-Dependent Attenuation of TLR9 Signaling by Gold Nanoparticles in Macrophages

(2011) C.-Y. Tsai et al.   JOURNAL OF IMMUNOLOGY

SiO2nanoparticles biocompatibility and their potential for gene delivery and silencing

(2011) Maria Ada Malvindi et al.   Nanoscale

TiO2nanoparticles induce insulin resistance in liver-derived cells both directly and via macrophage activation

(2011) Diana Gurevitch et al.   Nanotoxicology

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Gold nanoparticles for high-throughput genotyping of long-range haplotypes

(2011) Peng Chen et al.   Nature Nanotechnology

Alpha-alumina nanoparticles induce efficient autophagy-dependent cross-presentation and potent antitumour response

(2011) Haiyan Li et al.   Nature Nanotechnology

mTORC1 Senses Lysosomal Amino Acids Through an Inside-Out Mechanism That Requires the Vacuolar H+-ATPase

(2011) R. Zoncu et al.   SCIENCE

Advances in metal-induced oxidative stress and human disease

(2011) Klaudia Jomova et al.   TOXICOLOGY

The effect of TiO2 and Ag nanoparticles on reproduction and development of Drosophila melanogaster and CD-1 mice

(2011) Nicola A. Philbrook et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A functionalized single-walled carbon nanotube-induced autophagic cell death in human lung cells through Akt–TSC2-mTOR signaling

(2011) H-L Liu et al.   Cell Death & Disease

Gold Nanoparticles Promote Osteogenic Differentiation of Mesenchymal Stem Cells through p38 MAPK Pathway

(2010) Changqing Yi et al.   ACS Nano

Self-Catalyzed, Self-Limiting Growth of Glucose Oxidase-Mimicking Gold Nanoparticles

(2010) Weijie Luo et al.   ACS Nano

In Vivo Biodistribution and Clearance Studies Using Multimodal Organically Modified Silica Nanoparticles

(2010) Rajiv Kumar et al.   ACS Nano

Oxidative stress and toxicity of gold nanoparticles in Mytilus edulis

(2010) Sara Tedesco et al.   AQUATIC TOXICOLOGY

Effects of titanium dioxide nano-particles on growth and some histological parameters of zebrafish (Danio rerio) after a long-term exposure

(2010) Jinyuan Chen et al.   AQUATIC TOXICOLOGY

The effect of carboxydextran-coated superparamagnetic iron oxide nanoparticles on c-Jun N-terminal kinase-mediated apoptosis in human macrophages

(2010) Oleg Lunov et al.   BIOMATERIALS

Autophagy and oxidative stress associated with gold nanoparticles

(2010) Jasmine J. Li et al.   BIOMATERIALS

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Oxidative stress, insulin signaling, and diabetes

(2010) Justin L. Rains et al.   FREE RADICAL BIOLOGY AND MEDICINE

Toxicologic effects of gold nanoparticles in vivo by different administration routes

(2010) Zhang   International Journal of Nanomedicine

Comparative Cytotoxicity of Al2O3, CeO2, TiO2 and ZnO Nanoparticles to Human Lung Cells

(2010) In-Sun Kim et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Metabolic alterations and targeted therapies in prostate cancer

(2010) Richard Flavin et al.   JOURNAL OF PATHOLOGY

Nanoparticle-induced unfolding of fibrinogen promotes Mac-1 receptor activation and inflammation

(2010) Zhou J. Deng et al.   Nature Nanotechnology

Reactive oxygen species and insulin resistance: the good, the bad and the ugly

(2010) Tony Tiganis   TRENDS IN PHARMACOLOGICAL SCIENCES

PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

(2010) Xian-ping Dong et al.   Nature Communications

Regulation Mechanisms and Signaling Pathways of Autophagy

(2009) Congcong He et al.   Annual Review of Genetics

Reactive Oxygen Species Enhance Insulin Sensitivity

(2009) Kim Loh et al.   Cell Metabolism

Gold Nanoparticles of Diameter 1.4 nm Trigger Necrosis by Oxidative Stress and Mitochondrial Damage

(2009) Yu Pan et al.   Small

Silver nanoparticles induced heat shock protein 70, oxidative stress and apoptosis in Drosophila melanogaster

(2009) Maqusood Ahamed et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

PAMAM Nanoparticles Promote Acute Lung Injury by Inducing Autophagic Cell Death through the Akt-TSC2-mTOR Signaling Pathway

(2009) C. Li et al.   Journal of Molecular Cell Biology

The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function

(2008) Vladimir Marshansky et al.   CURRENT OPINION IN CELL BIOLOGY

The cell biology of autophagy in metazoans: a developing story

(2008) A. Melendez et al.   DEVELOPMENT

Potential Oxidative Stress of Gold Nanoparticles by Induced-NO Releasing in Serum

(2008) Hong Ying Jia et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE