Fate determination in mesenchymal stem cells: a perspective from histone-modifying enzymes

Distinct patterns of histone modifications at cardiac-specific gene promoters between cardiac stem cells and mesenchymal stem cells

(2013) Meijing Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Genome-wide map of quantified epigenetic changes during in vitro chondrogenic differentiation of primary human mesenchymal stem cells

(2013) Sarah R Herlofsen et al.   BMC GENOMICS

Epigenetics of Reprogramming to Induced Pluripotency

(2013) Bernadett Papp et al.   CELL

Depletion of histone demethylase KDM2A enhanced the adipogenic and chondrogenic differentiation potentials of stem cells from apical papilla

(2013) Rui Dong et al.   EXPERIMENTAL CELL RESEARCH

PPARγ forms a bridge between DNA methylation and histone acetylation at the C/EBPα gene promoter to regulate the balance between osteogenesis and adipogenesis of bone marrow stromal cells

(2013) Qing-hua Zhao et al.   FEBS Journal

ESET histone methyltransferase regulates osteoblastic differentiation of mesenchymal stem cells during postnatal bone development

(2013) Kevin A. Lawson et al.   FEBS LETTERS

Valproic acid promotes neuronal differentiation by induction of neuroprogenitors in human bone-marrow mesenchymal stromal cells

(2013) Sin-Gu Jeong et al.   NEUROSCIENCE LETTERS

Modification of Histone Acetylation Facilitates Hepatic Differentiation of Human Bone Marrow Mesenchymal Stem Cells

(2013) Xuejun Dong et al.   PLoS One

EZH2andKDM6AAct as an Epigenetic Switch to Regulate Mesenchymal Stem Cell Lineage Specification

(2013) Sarah Hemming et al.   STEM CELLS

Arid5b facilitates chondrogenesis by recruiting the histone demethylase Phf2 to Sox9-regulated genes

(2013) Kenji Hata et al.   Nature Communications

Chromatin Modifications as Determinants of Muscle Stem Cell Quiescence and Chronological Aging

(2013) Ling Liu et al.   Cell Reports

Dynamic and distinct histone modifications modulate the expression of key adipogenesis regulatory genes

(2012) Qiongyi Zhang et al.   CELL CYCLE

Histone Demethylases KDM4B and KDM6B Promotes Osteogenic Differentiation of Human MSCs

(2012) Ling Ye et al.   Cell Stem Cell

Epigenetic Regulation of Adipogenesis by PHF2 Histone Demethylase

(2012) Y. Okuno et al.   DIABETES

Endothelial differentiation of adipose-derived mesenchymal stem cells is improved by epigenetic modifying drug BIX-01294

(2012) Mihaela Culmes et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations

(2012) Michael T. McCabe et al.   NATURE

Histone methylation: a dynamic mark in health, disease and inheritance

(2012) Eric L. Greer et al.   NATURE REVIEWS GENETICS

Upregulation of miR-22 Promotes Osteogenic Differentiation and Inhibits Adipogenic Differentiation of Human Adipose Tissue-Derived Mesenchymal Stem Cells by Repressing HDAC6 Protein Expression

(2012) Shan Huang et al.   STEM CELLS AND DEVELOPMENT

Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease

(2012) Jill S Butler et al.   Epigenomics

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

EZH2 Regulates Neuronal Differentiation of Mesenchymal Stem Cells through PIP5K1C-dependent Calcium Signaling

(2011) Yung-Luen Yu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative Epigenomic Analysis of Murine and Human Adipogenesis

(2010) Tarjei S. Mikkelsen et al.   CELL

Chromatin Structure and Gene Expression Programs of Human Embryonic and Induced Pluripotent Stem Cells

(2010) Matthew G. Guenther et al.   Cell Stem Cell

Redundant Control of Adipogenesis by Histone Deacetylases 1 and 2

(2010) Michael Haberland et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Modifiers, YY1 and p300, Regulate the Expression of Cartilage-specific Gene, Chondromodulin-I, in Mesenchymal Stem Cells

(2010) Tomoki Aoyama et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Histone Demethylase LSD1 Regulates Adipogenesis

(2010) Melina M. Musri et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A role for Gcn5 in cardiomyocyte differentiation of rat mesenchymal stem cells

(2010) Li Li et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

CDK1-dependent phosphorylation of EZH2 suppresses methylation of H3K27 and promotes osteogenic differentiation of human mesenchymal stem cells

(2010) Yongkun Wei et al.   NATURE CELL BIOLOGY

Chromatin Signatures in Multipotent Human Hematopoietic Stem Cells Indicate the Fate of Bivalent Genes during Differentiation

(2009) Kairong Cui et al.   Cell Stem Cell

Histone acetyl transferases as emerging drug targets

(2009) Frank J. Dekker et al.   DRUG DISCOVERY TODAY

The Peroxisome Proliferator-Activated Receptor  /Retinoid X Receptor   Heterodimer Targets the Histone Modification Enzyme PR-Set7/Setd8 Gene and Regulates Adipogenesis through a Positive Feedback Loop

(2009) K.-i. Wakabayashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Role of Jhdm2a in regulating metabolic gene expression and obesity resistance

(2009) Keisuke Tateishi et al.   NATURE

BCOR regulates mesenchymal stem cell function by epigenetic mechanisms

(2009) Zhipeng Fan et al.   NATURE CELL BIOLOGY

Genome-Wide Analysis of Histone H3 Lysine9 Modifications in Human Mesenchymal Stem Cell Osteogenic Differentiation

(2009) Jiang Tan et al.   PLoS One

Histone modifying enzymes: Structures, mechanisms, and specificities

(2008) Ronen Marmorstein et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis

(2008) J. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Adipogenic Acetyltransferase Tip60 Targets Activation Function 1 of Peroxisome Proliferator-Activated Receptor γ

(2007) Olivier van Beekum et al.   ENDOCRINOLOGY