FGF21 does not require interscapular brown adipose tissue and improves liver metabolic profile in animal models of obesity and insulin-resistance
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Title
FGF21 does not require interscapular brown adipose tissue and improves liver metabolic profile in animal models of obesity and insulin-resistance
Authors
Keywords
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Journal
Scientific Reports
Volume 5, Issue 1, Pages -
Publisher
Springer Nature
Online
2015-07-08
DOI
10.1038/srep11382
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Note: Only part of the references are listed.- Pharmacokinetics (PK), Pharmacodynamics (PD) and Integrated PK/PD Modeling of a Novel Long Acting FGF21 Clinical Candidate PF-05231023 in Diet-Induced Obese and Leptin-Deficient Obese Mice
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- (2014) J M Gallego-Escuredo et al. INTERNATIONAL JOURNAL OF OBESITY
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- (2013) Zhuofeng Lin et al. Cell Metabolism
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- (2013) William L. Holland et al. Cell Metabolism
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- (2013) Gregory Gaich et al. Cell Metabolism
- Fibroblast Growth Factor 21 Improves Insulin Resistance and Ameliorates Renal Injury indb/dbMice
- (2013) H. W. Kim et al. ENDOCRINOLOGY
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- (2013) João Paulo G. Camporez et al. ENDOCRINOLOGY
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- (2013) Min Lu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- LY2405319, an Engineered FGF21 Variant, Improves the Metabolic Status of Diabetic Monkeys
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- (2013) Richard Smith et al. PLoS One
- βKlotho Is Required for Fibroblast Growth Factor 21 Effects on Growth and Metabolism
- (2012) Xunshan Ding et al. Cell Metabolism
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- (2012) f. M. Fisher et al. GENES & DEVELOPMENT
- Activation of the Farnesoid X Receptor Induces Hepatic Expression and Secretion of Fibroblast Growth Factor 21
- (2012) Holly A. Cyphert et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- G protein–coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice
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- (2012) Kristin I. Stanford et al. JOURNAL OF CLINICAL INVESTIGATION
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- Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo
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- (2012) I. N. Foltz et al. Science Translational Medicine
- The breadth of FGF21's metabolic actions are governed by FGFR1 in adipose tissue
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- (2011) Elayne Hondares et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Unknown
- (2011) Dionysios Chartoumpekis et al. MOLECULAR MEDICINE
- FGF19 Regulates Cell Proliferation, Glucose and Bile Acid Metabolism via FGFR4-Dependent and Independent Pathways
- (2011) Ai-Luen Wu et al. PLoS One
- Research Resource: Comprehensive Expression Atlas of the Fibroblast Growth Factor System in Adult Mouse
- (2010) Klementina Fon Tacer et al. MOLECULAR ENDOCRINOLOGY
- Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice
- (2008) J. Xu et al. DIABETES
- Fibroblast Growth Factor 21 Corrects Obesity in Mice
- (2008) Tamer Coskun et al. ENDOCRINOLOGY
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