Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library

Chemical ligation methods for the tagging of DNA-encoded chemical libraries

(2015) Anthony D Keefe et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

DNA-Encoded Chemical Libraries: Advancing beyond Conventional Small-Molecule Libraries

(2014) Raphael M. Franzini et al.   ACCOUNTS OF CHEMICAL RESEARCH

Transcription of Click-Linked DNA in Human Cells

(2014) Charles N. Birts et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Application of encoded library technology (ELT) to a protein–protein interaction target: Discovery of a potent class of integrin lymphocyte function-associated antigen 1 (LFA-1) antagonists

(2014) Christopher S. Kollmann et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Encoded Library Technology as a Source of Hits for the Discovery and Lead Optimization of a Potent and Selective Class of Bactericidal Direct Inhibitors of Mycobacterium tuberculosis InhA

(2014) Lourdes Encinas et al.   JOURNAL OF MEDICINAL CHEMISTRY

Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction

(2014) Aidan G Gilmartin et al.   Nature Chemical Biology

DNA Modification under Mild Conditions by Suzuki-Miyaura Cross-Coupling for the Generation of Functional Probes

(2013) Lukas Lercher et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of 1-(1,3,5-triazin-2-yl)piperidine-4-carboxamides as inhibitors of soluble epoxide hydrolase

(2013) Reema K. Thalji et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of Thieno[3,2-d]pyrimidine-6-carboxamides as Potent Inhibitors of SIRT1, SIRT2, and SIRT3

(2013) Jeremy S. Disch et al.   JOURNAL OF MEDICINAL CHEMISTRY

In vitro and in vivo characterization of a novel soluble epoxide hydrolase inhibitor

(2013) Patricia L. Podolin et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

5-Aryl-4-carboxamide-1,3-oxazoles: Potent and selective GSK-3 inhibitors

(2012) Gabriella Gentile et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of Highly Potent and Selective Small Molecule ADAMTS-5 Inhibitors That Inhibit Human Cartilage Degradation via Encoded Library Technology (ELT)

(2012) Hongfeng Deng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Assessing the biocompatibility of click-linked DNA in Escherichia coli

(2012) A. Pia Sanzone et al.   NUCLEIC ACIDS RESEARCH

Small-molecule discovery from DNA-encoded chemical libraries

(2011) Ralph E. Kleiner et al.   CHEMICAL SOCIETY REVIEWS

Biocompatible artificial DNA linker that is read through by DNA polymerases and is functional in Escherichia coli

(2011) A. H. El-Sagheer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selecting chemicals: the emerging utility of DNA-encoded libraries

(2010) Matthew A. Clark   CURRENT OPINION IN CHEMICAL BIOLOGY

Postsynthetic Guanine Arylation of DNA by Suzuki−Miyaura Cross-Coupling

(2010) Alireza Omumi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and Polymerase Chain Reaction Amplification of DNA Strands Containing an Unnatural Triazole Linkage

(2009) Afaf H. El-Sagheer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design, synthesis and selection of DNA-encoded small-molecule libraries

(2009) Matthew A Clark et al.   Nature Chemical Biology

Click–Click–Click: Single to Triple Modification of DNA

(2008) Philipp M. E. Gramlich et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design and synthesis of a novel DNA-encoded chemical library using Diels-Alder cycloadditions

(2008) Fabian Buller et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS