Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction

Binding of a Third Metal Ion by the Human Phosphatases PP2Cα and Wip1 Is Required for Phosphatase Activity

(2013) Kan Tanoue et al.   BIOCHEMISTRY

The expanding field of SILAC

(2012) Shao-En Ong   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Optimization of a Cyclic Peptide Inhibitor of Ser/Thr Phosphatase PPM1D (Wip1)

(2011) Ryo Hayashi et al.   BIOCHEMISTRY

Oncogenic phosphatase Wip1 is a novel prognostic marker for lung adenocarcinoma patient survival

(2011) Naoyuki Satoh et al.   CANCER SCIENCE

Regulation of the Wip1 phosphatase and its effects on the stress response Julie Lowe, Hyukjin Cha, Mi-Ok Lee, Sharlyn J. Mazur, Ettore Appella, Albert J. Fornace Jr.

(2011) Julie Lowe   Frontiers in Bioscience-Landmark

A Proteome-wide, Quantitative Survey of In Vivo Ubiquitylation Sites Reveals Widespread Regulatory Roles

(2011) Sebastian A. Wagner et al.   MOLECULAR & CELLULAR PROTEOMICS

Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome

(2011) Woong Kim et al.   MOLECULAR CELL

PPM1D gene amplification and overexpression in breast cancer: a qRT-PCR and chromogenic in situ hybridization study

(2010) Maryou B Lambros et al.   MODERN PATHOLOGY

Tiling Path Genomic Profiling of Grade 3 Invasive Ductal Breast Cancers

(2009) R. Natrajan et al.   CLINICAL CANCER RESEARCH

PPM1D Is a Potential Therapeutic Target in Ovarian Clear Cell Carcinomas

(2009) D. S.P. Tan et al.   CLINICAL CANCER RESEARCH

The therapeutic potential of phosphatase inhibitors

(2009) Viktor V Vintonyak et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Genetic Alterations and Oncogenic Pathways Associated with Breast Cancer Subtypes

(2009) X. Hu et al.   MOLECULAR CANCER RESEARCH

Design, synthesis and selection of DNA-encoded small-molecule libraries

(2009) Matthew A Clark et al.   Nature Chemical Biology

The type 2C phosphatase Wip1: An oncogenic regulator of tumor suppressor and DNA damage response pathways

(2008) Xiongbin Lu et al.   CANCER AND METASTASIS REVIEWS

Characterization of the Active Site and a Unique Uncompetitive Inhibitor of the PPM1-Type Protein Phosphatase PPM1D

(2008) Yoshiro Chuman et al.   PROTEIN AND PEPTIDE LETTERS

Structural Analysis of the PP2C Phosphatase tPphA from Thermosynechococcus elongatus: A Flexible Flap Subdomain Controls Access to the Catalytic Site

(2007) Christine Schlicker et al.   JOURNAL OF MOLECULAR BIOLOGY