Susceptibility loci in lung cancer and COPD: association of IREB2 and FAM13A with pulmonary diseases

Regulation of nuclear–cytoplasmic shuttling and function of Family with sequence similarity 13, member A (Fam13a), by B56-containing PP2As and Akt

(2015) Zhigang Jin et al.   MOLECULAR BIOLOGY OF THE CELL

Targeting Rho-GTPases in immune cell migration and inflammation

(2014) Maté Biro et al.   BRITISH JOURNAL OF PHARMACOLOGY

Rho GTPases in the regulation of pulmonary vascular barrier function

(2014) Lucie Duluc et al.   CELL AND TISSUE RESEARCH

Moving beyond genetics: isFAM13Aa major biological contributor in lung physiology and chronic lung diseases?

(2014) Harriet Corvol et al.   JOURNAL OF MEDICAL GENETICS

Association of FAM13A polymorphisms with COPD and COPD-related phenotypes in Han Chinese

(2013) Bo Wang et al.   CLINICAL BIOCHEMISTRY

Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility

(2013) Mateusz Siedlinski et al.   HUMAN GENETICS

Cumulative Risk Impact of Five Genetic Variants Associated with Papillary Thyroid Carcinoma

(2013) Sandya Liyanarachchi et al.   THYROID

CHRNA3/5,IREB2, andADCY2Are Associated with Severe Chronic Obstructive Pulmonary Disease in Poland

(2012) Megan Hardin et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The Association of Genome-Wide Significant Spirometric Loci with Chronic Obstructive Pulmonary Disease Susceptibility

(2011) Peter J. Castaldi et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Genetic analysis of IREB2, FAM13A and XRCC5 variants in Chinese Han patients with chronic obstructive pulmonary disease

(2011) Yi Guo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of IREB2 and transforming growth factor beta-1 genetic variants in COPD: a replication case-control study

(2011) Sally L Chappell et al.   BMC Medical Genetics

Individual and Cumulative Effects of GWAS Susceptibility Loci in Lung Cancer: Associations after Sub-Phenotyping for COPD

(2011) Robert P. Young et al.   PLoS One

Loci Identified by Genome-wide Association Studies Influence Different Disease-related Phenotypes in Chronic Obstructive Pulmonary Disease

(2010) Sreekumar G. Pillai et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Variants in FAM13A are associated with chronic obstructive pulmonary disease

(2010) Michael H Cho et al.   NATURE GENETICS

Tumorigenic Properties of Iron Regulatory Protein 2 (IRP2) Mediated by Its Specific 73-Amino Acids Insert

(2010) Carmen Maffettone et al.   PLoS One

Multiple Independent Loci at Chromosome 15q25.1 Affect Smoking Quantity: a Meta-Analysis and Comparison with Lung Cancer and COPD

(2010) Nancy L. Saccone et al.   PLoS Genetics

Integration of Genomic and Genetic Approaches Implicates IREB2 as a COPD Susceptibility Gene

(2009) Dawn L. DeMeo et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Haplotype and Cell Proliferation Analyses of Candidate Lung Cancer Susceptibility Genes on Chromosome 15q24-25.1

(2009) Y. Liu et al.   CANCER RESEARCH

The CHRNA5-CHRNA3-CHRNB4 Nicotinic Receptor Subunit Gene Cluster Affects Risk for Nicotine Dependence in African-Americans and in European-Americans

(2009) N. L. Saccone et al.   CANCER RESEARCH

Transcription Deregulation at the 15q25 Locus in Association with Lung Adenocarcinoma Risk

(2009) F. S. Falvella et al.   CLINICAL CANCER RESEARCH

COPD prevalence is increased in lung cancer, independent of age, sex and smoking history

(2009) R. P. Young et al.   EUROPEAN RESPIRATORY JOURNAL

Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5

(2009) Jen C. Wang et al.   HUMAN MOLECULAR GENETICS

Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function

(2009) Dana B Hancock et al.   NATURE GENETICS

A Genome-Wide Association Study in Chronic Obstructive Pulmonary Disease (COPD): Identification of Two Major Susceptibility Loci

(2009) Sreekumar G. Pillai et al.   PLoS Genetics

Particulate Matter in Cigarette Smoke Alters Iron Homeostasis to Produce a Biological Effect

(2008) Andrew J. Ghio et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The CHRNA5-A3 Region on Chromosome 15q24-25.1 Is a Risk Factor Both for Nicotine Dependence and for Lung Cancer

(2008) Margaret R. Spitz et al.   JNCI-Journal of the National Cancer Institute

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

(2008) Thorgeir E. Thorgeirsson et al.   NATURE

A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25

(2008) Rayjean J. Hung et al.   NATURE

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

(2008) Christopher I Amos et al.   NATURE GENETICS

Common origins of lung cancer and COPD

(2008) A McGarry Houghton et al.   NATURE MEDICINE