(Z)3,4,5,4′-trans-tetramethoxystilbene, a new analogue of resveratrol, inhibits gefitinb-resistant non-small cell lung cancer via selectively elevating intracellular calcium level

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging

(2016) Linda S. Steelman et al.   Aging-US

Celastrol Induces Apoptosis in Gefitinib-Resistant Non-Small Cell Lung Cancer Cells via Caspases-Dependent Pathways and Hsp90 Client Protein Degradation

(2014) Xing-Xing Fan et al.   MOLECULES

Oncogenic driver mutations in patients with non-small-cell lung cancer at various clinical stages

(2013) J. X. Zhou et al.   ANNALS OF ONCOLOGY

Signal integration by mTORC1 coordinates nutrient input with biosynthetic output

(2013) Christian C. Dibble et al.   NATURE CELL BIOLOGY

Amino acid signalling upstream of mTOR

(2013) Jenna L. Jewell et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Resveratrol Induces Premature Senescence in Lung Cancer Cells via ROS-Mediated DNA Damage

(2013) Hongmei Luo et al.   PLoS One

Different susceptibility of colon cancer DLD-1 and LOVO cell lines to apoptosis induced by DMU-212, a synthetic resveratrol analogue

(2013) Hanna Piotrowska et al.   TOXICOLOGY IN VITRO

Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells

(2013) V KW Wong et al.   Cell Death & Disease

Discovery of a Mutant-Selective Covalent Inhibitor of EGFR that Overcomes T790M-Mediated Resistance in NSCLC

(2013) A. O. Walter et al.   Cancer Discovery

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Resveratrol: A Natural Polyphenol with Multiple Chemopreventive Properties (Review)

(2012) Fabrizia Brisdelli et al.   CURRENT DRUG METABOLISM

Resveratrol analogue 3,4,4′,5-tetramethoxystilbene inhibits growth, arrests cell cycle and induces apoptosis in ovarian SKOV‐3 and A-2780 cancer cells

(2012) Hanna Piotrowska et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy

(2012) W-Y Shi et al.   Cell Death & Disease

Resveratrol: French Paradox Revisited

(2012) Betul Catalgol et al.   Frontiers in Pharmacology

Rebiopsy of Lung Cancer Patients with Acquired Resistance to EGFR Inhibitors and Enhanced Detection of the T790M Mutation Using a Locked Nucleic Acid-Based Assay

(2011) M. E. Arcila et al.   CLINICAL CANCER RESEARCH

JNK Signaling Promotes Intestinal Tumorigenesis Through Activation of mTOR Complex 1 in ApcΔ716 Mice

(2011) Teruaki Fujishita et al.   GASTROENTEROLOGY

Rapamycin passes the torch: a new generation of mTOR inhibitors

(2011) Don Benjamin et al.   NATURE REVIEWS DRUG DISCOVERY

Mammalian target of rapamycin: Biological function and target for novel anticancer agents

(2010) E. B. Borders et al.   AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY

Targeting the pro-death and pro-survival functions of autophagy as novel therapeutic strategies in cancer

(2010) Kevin Dalby et al.   Autophagy

Targeting cancer cells through autophagy for anticancer therapy

(2010) Sandra Turcotte et al.   CURRENT OPINION IN CELL BIOLOGY

BCR-ABL tyrosine kinase inhibitors in the treatment of Philadelphia chromosome positive chronic myeloid leukemia: A review

(2010) Xin An et al.   LEUKEMIA RESEARCH

Apoptosis and Autophagy: Decoding Calcium Signals that Mediate Life or Death

(2010) M. W. Harr et al.   Cold Spring Harbor Perspectives in Biology

Cancer Prevention and Treatment with Resveratrol: From Rodent Studies to Clinical Trials

(2009) A. Bishayee   Cancer Prevention Research

EGFR Signals to mTOR Through PKC and Independently of Akt in Glioma

(2009) Q.-W. Fan et al.   Science Signaling

Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span

(2008) Kevin J. Pearson et al.   Cell Metabolism