Saikosaponin-d, a novel SERCA inhibitor, induces autophagic cell death in apoptosis-defective cells

Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development

(2013) Mayur V. Jain et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Guidelines for the use and interpretation of assays for monitoring autophagy

(2012) Daniel J. Klionsky et al.   Autophagy

Discovery of novel SERCA inhibitors by virtual screening of a large compound library

(2011) Christopher Elam et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Reactive oxygen species-mediated apoptosis contributes to chemosensitization effect of saikosaponins on cisplatin-induced cytotoxicity in cancer cells

(2011) Qiong Wang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Targeting autophagy during cancer therapy to improve clinical outcomes

(2011) Jean M. Mulcahy Levy et al.   PHARMACOLOGY & THERAPEUTICS

Targeting the pro-death and pro-survival functions of autophagy as novel therapeutic strategies in cancer

(2010) Kevin Dalby et al.   Autophagy

Targeting cancer cells through autophagy for anticancer therapy

(2010) Sandra Turcotte et al.   CURRENT OPINION IN CELL BIOLOGY

Alisol B, a Novel Inhibitor of the Sarcoplasmic/Endoplasmic Reticulum Ca2+ ATPase Pump, Induces Autophagy, Endoplasmic Reticulum Stress, and Apoptosis

(2010) B. Y. K. Law et al.   MOLECULAR CANCER THERAPEUTICS

Gemcitabine Induces the VMP1 -Mediated Autophagy Pathway to Promote Apoptotic Death in Human Pancreatic Cancer Cells

(2010) Romina Pardo et al.   PANCREATOLOGY

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Cytotoxic activity and inhibitory effect on nitric oxide production of triterpene saponins from the roots of Physospermum verticillatum (Waldst & Kit) (Apiaceae)

(2009) Rosa Tundis et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Inhibition of the ER Ca 2+ pump forces multidrug-resistant cells deficient in Bak and Bax into necrosis

(2009) Katja Janssen et al.   JOURNAL OF CELL SCIENCE

Mechanistic study of saikosaponin-d (Ssd) on suppression of murine T lymphocyte activation

(2009) Vincent Kam Wai Wong et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells

(2009) María Salazar et al.   JOURNAL OF CLINICAL INVESTIGATION

CHOP-independent apoptosis and pathway-selective induction of the UPR in developing plasma cells

(2009) Silvia Masciarelli et al.   MOLECULAR IMMUNOLOGY

A Molecule Targeting VHL-Deficient Renal Cell Carcinoma that Induces Autophagy

(2008) Sandra Turcotte et al.   CANCER CELL

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells

(2008) J Li et al.   CELL DEATH AND DIFFERENTIATION

DNA-Ligase IV and DNA-Protein Kinase Play a Critical Role in Deficient Caspases Activation in Apoptosis-resistant Cancer Cells by Using Doxorubicin

(2008) Claudia Friesen et al.   MOLECULAR BIOLOGY OF THE CELL

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY