Article
Chemistry, Physical
Yu-Fang Huang, Wen-Chi Huang, Pei-Kai Hsu, Jenn-Ming Song, Alexandre Gloter, Shih-Yun Chen
Summary: This study successfully synthesized magnetically-manipulatable and reusable SERS active buoyant substrates, Ag@SiO2@Fe3O4 composite hollow spheres, which consist of Fe3O4 inner shell, SiO2 outer shell, and Ag nanoparticles on the surface. The hollow structure exhibited stronger SERS signal intensity compared to solid cores, can be easily concentrated and separated under external magnetic field, resulting in a more augmented SERS effect. These ferromagnetic hollow composites also demonstrated the possibility of reusing for SERS measurements.
APPLIED SURFACE SCIENCE
(2021)
Article
Materials Science, Multidisciplinary
Tianjiao Zhang, Jialei Miao, Chun Huang, Zheng Bian, Maoxin Tian, Haohan Chen, Ruihuan Duan, Lin Wang, Zheng Liu, Jingsi Qiao, Yang Xu, Bin Yu, Yuda Zhao
Summary: In this study, high-work-function 2D semimetals have been used as the gate to fabricate high-performance MESFET with low power consumption. TiS2 with an ultrahigh work function of 6.6 eV forms the largest Schottky barrier height with MoS2. TiS2/MoS2 MESFETs display a sub-0.1 V threshold voltage and a small subthreshold swing of 73 mV/dec.
MATERIALS & DESIGN
(2023)
Article
Chemistry, Physical
Sikandar Aftab, Ms Samiya, Mian Sabir Hussain, Ehsan Elahi, Saqlain Yousuf, Hafiz Muhammad Salman Ajmal, Muhammad Waqas Iqbal, Muhammad Zahir Iqbal
Summary: The alignment of Fermi levels between electrodes and 2D materials is crucial for characterizing sensors, and this research demonstrates modulation of the Schottky barrier height can affect the response to hydrogen concentrations, offering a potential solution for developing cost-effective, faster, and room temperature sensors based on 2D materials.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2021)
Article
Chemistry, Multidisciplinary
Zhenping Wang, Nasir Ali, Tien Dat Ngo, Hoseong Shin, Sungwon Lee, Won Jong Yoo
Summary: High-mobility field-effect transistors (FETs) are achieved by introducing few-layer PdSe2 flakes as channels and directly depositing semimetal antimony (Sb) as drain-source electrodes. The formation of clean and defect-free van der Waals (vdW) stackings at the Sb-PdSe2 heterointerfaces boosts the transport characteristics, while the use of layered h-BN as buffer layers eliminates interfacial disorders and significantly increases electron mobility.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Engineering, Electrical & Electronic
Tania K. Naqvi, Abhilash Bajpai, Sarthak Dwivedi, Manish Bhaiyya, Sanket Goel, Prabhat K. Dwivedi
Summary: In this study, a low-cost, label-free flexible paper-based microfluidic SERS sensor was developed for thiram detection. Hydrophilic wells of different sizes were created on paper using wax-coated mould printing, and the hydrophilic nature of the wells was confirmed. Silver nanoparticles decorated graphene oxide nano-hybrid (Ag-rGO) was synthesized and drop-casted onto the wells for thiram detection, achieving fM sensitivity with a low limit of detection and high enhancement factor. The reproducibility and uniformity of the fabricated substrates were tested, showing good results. The Ag-rGO/wax paper (Ag-rGO/WP) SERS sensor has the potential to be used as a portable sensing platform for food safety applications.
SENSORS AND ACTUATORS A-PHYSICAL
(2023)
Article
Chemistry, Analytical
A. Zabelina, A. Trelin, A. Skvortsova, D. Zabelin, V Burtsev, E. Miliutina, O. Lyutakov
Summary: Surface-enhanced Raman spectroscopy (SERS) is an analytical method with high potential in medicine, allowing the precise detection of specific analytes close to a single-molecule detection limit. In this work, an advanced SERS approach was used to detect cancer-related miRNA-21 in blood plasma, achieving reliable and repeatable quantitative detection.
ANALYTICA CHIMICA ACTA
(2023)
Article
Nanoscience & Nanotechnology
Yingnan Sun, Yuhan Song, Haohan Sun, Qingqing Tian, Qian Wang, Yongshu Liu, Shusheng Zhang
Summary: This study develops a strategy to transform superhydrophobic surfaces into large label-free SERS substrates with uniform and dense hot spots, enabling sensitive and high-throughput detection.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Physical
Yuan Ren, Zhiyuan He, Bin Dong, Changan Wang, Zhaohui Zeng, Qixin Li, Zhitao Chen, Liuan Li, Ningyang Liu
Summary: This study focuses on the electrical properties of Ni/n-GaN Schottky barrier diodes fabricated on GaN bulk substrates with different crystal orientations. The results show that the crystal orientation of the GaN substrate has a significant impact on the Schottky barrier height, reverse leakage current, and barrier inhomogeneity of the devices.
JOURNAL OF ALLOYS AND COMPOUNDS
(2022)
Article
Chemistry, Multidisciplinary
Xingang Chen, Lei Zhu, Zhipeng Ma, Meilin Wang, Rui Zhao, Yueyue Zou, Yijie Fan
Summary: Industrial wastewater containing organic pollutants poses a serious threat to the environment and human health. Developing a multifunctional and reusable substrate based on surface-enhanced Raman scattering (SERS) for detecting and degrading these pollutants is of great significance.
Article
Materials Science, Coatings & Films
Dinusha Herath Mudiyanselage, Dawei Wang, Houqiang Fu
Summary: In this study, ultrawide bandgap beta-(AlxGa1-x)(2)O-3 vertical Schottky barrier diodes on (010) beta-Ga2O3 substrates were fabricated and demonstrated. The fabricated devices exhibited excellent rectification properties with a high on/off ratio, a low turn-on voltage, and a low on-resistance. The leakage mechanisms of the devices were analyzed and it was found that Poole-Frenkel emission and trap-assisted tunneling were the main mechanisms at high and low temperatures, respectively. This work provides an important reference for the future development of ultrawide bandgap beta-(AlxGa1-x)(2)O-3 power electronics, RF electronics, and ultraviolet photonics.
JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A
(2023)
Article
Chemistry, Physical
M. Al Huwayz, D. A. Jameel, Walter M. de Azevedo, Jorlandio F. Felix, N. Al Saqri, O. M. Lemine, S. Abu Alrub, M. Henini
Summary: This study investigates the impact of gamma radiation on the electrical properties of InAs/InGaAs quantum dot-based laser structures grown on both GaAs (Sample A) and Si (Sample B) substrates using molecular beam epitaxy. The results show that the electrical properties of the lasers change due to gamma radiation exposure, and the extent of the change depends on the substrate used for growth. Furthermore, this study highlights the importance of considering substrate materials in the design of radiation-hardened electronic devices.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Chemistry, Multidisciplinary
Zhenming Wang, Jianxun Liu, Jiawei Wang, Zongjun Ma, Delai Kong, Shouzhen Jiang, Dan Luo, Yan Jun Liu
Summary: This paper presents a cost-effective, large-sized, and highly reproducible SERS substrate prepared by nanosphere lithography technique. By manipulating the geometry of the Ag metasurface deposited on the substrate and coating a thin layer of graphene oxide, high enhancement factor and low detection limit of SERS performance have been achieved. Experimental results demonstrate the potential application value of this method for trace detection in fields like food safety control and environmental monitoring.
Article
Chemistry, Analytical
Zhi-Qin Geng, Di Xu, Yuhang Song, Wei-Peng Wang, Yun-Peng Li, Cai-Qin Han, Guo-Hai Yang, Lu-Lu Qu, Pulickel M. Ajayan
Summary: A recyclable surface-enhanced Raman scattering (SERS) substrate was developed for label-free detection of bilirubin (BR) in complex biological samples. By modifying functional boron nitride (M-BN) monolayer nanosheets on silver nanoarrays (Ag NRs), the detection sensitivity and long-term stability of the substrate were significantly improved. The substrate provides a simple yet promising platform for nondestructive detection of BR with a low detection limit and excellent reusability.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Biochemical Research Methods
Shazia Rashid, Faisal Bashir, Farooq A. Khanday, M. Rafiq Beigh
Summary: In this work, an improved sensitivity L-Shaped Schottky Barrier FET biosensing device is demonstrated. The device utilizes dual material gate with different work functions and Hafnium Oxide as the gate dielectric. The electrical characteristics of biomolecules modulate the Schottky Barrier width, leading to changes in the device's current. Comparative analysis with conventional devices reveals better sensitivity performance in the proposed device for both neutral and charged biomolecules, as well as improvements in sensitivity parameters and selectivity. Additionally, the proposed device shows better sensitivity performance at low and high temperatures compared to state-of-the-art biosensing devices.
IEEE TRANSACTIONS ON NANOBIOSCIENCE
(2022)
Article
Spectroscopy
Dechan Lu, Rongyuan Cai, Yuqin Liao, Ruiyun You, Yudong Lu
Summary: In this study, a simple, efficient, and label-free surface enhanced Raman scattering (SERS) method was developed for the detection of uric acid (UA) content. The method showed a linear response to UA and good recoveries were obtained for the sensing of sweat. Therefore, the developed SERS substrate has potential applications in healthcare monitoring.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Immunology
James John, Kripa Shanker Kasudhan, Reba Kanungo, Savitri Sharma, Vaishali Dohe, K. Prashanth
INDIAN JOURNAL OF MEDICAL MICROBIOLOGY
(2017)
Article
Materials Science, Ceramics
Anil Kumar Pal, Sudipta Som, Chung-Hsin Lu
CERAMICS INTERNATIONAL
(2018)
Article
Biochemical Research Methods
Suresh Sah, Priyanka Bordoloi, D. Vijaya, Satish Kumar Amarnath, Sheela C. Devi, V. A. Indumathi, K. Prashanth
JOURNAL OF MICROBIOLOGICAL METHODS
(2018)
Article
Polymer Science
Anil Kumar Pal, Elisabetta Labella, Nicholas J. Goddard, Ruchi Gupta
MACROMOLECULAR CHEMISTRY AND PHYSICS
(2019)
Article
Materials Science, Multidisciplinary
P. Nandhagopal, Anil Kumar Pal, D. Bharathi Mohan
Article
Physics, Applied
Anil Kumar Pal, Goutam Kumar Chandra, Siva Umapathy, D. Bharathi Mohan
JOURNAL OF APPLIED PHYSICS
(2020)
Article
Chemistry, Analytical
Anil K. Pal, Nicholas J. Goddard, Hazel J. Dixon, Ruchi Gupta
Review
Medicine, Research & Experimental
Pownraj Brindangnanam, Ajit Ramesh Sawant, K. Prashanth, Mohane Selvaraj Coumar
Summary: Understanding the structure and function of efflux transporters is crucial for overcoming antimicrobial resistance. Research focuses on different types of pumps, their substrate specificities, and pump inhibitors. In-depth knowledge of pumps can lead to the development of new treatment approaches to combat the emerging AMR crisis.
Article
Nanoscience & Nanotechnology
Binaya Kumar Sahu, Anil Pal, S. T. Reshma, A. Das
Summary: The study reports the fabrication of a highly efficient Ag SERS substrate and verifies the existence of the Raman A(1g) mode in rutile SnO2 quantum dots. It also discovers the presence of an intense IR-active E-u (TO) mode in 25 nm size crystalline SnO2, suggesting an explanation based on the gradient-field Raman (GFR) effect.
ACS APPLIED NANO MATERIALS
(2022)
Article
Microbiology
Ashutosh Kumar Amar, Ajit Ramesh Sawant, Meerabai Manoharan, Archana Tomar, Sujatha Sistla, K. Prashanth
Summary: This study reports the genomic sequences of A. lactucae strains isolated from immunocompromised patients admitted to a referral hospital in India. These strains harbor multiple resistance determinants, including metallo-beta-lactamase (bla(NDM-1)).
MICROBIOLOGY RESOURCE ANNOUNCEMENTS
(2023)
Article
Immunology
Ajit Ramesh Sawant, Sudhakar Pagal, Ashutosh Kumar Amar, Lipsa Panda, Sheela C. devi, P. Shashikala, Reba Kanungo, K. Prashanth
Summary: This study investigated the factors contributing to tigecycline resistance in clinical isolates of Acinetobacter baumannii. The results showed a strong correlation between mutations in efflux pump regulatory genes and the expression of efflux pump genes with tigecycline resistance. Additionally, TNAB isolates exhibited a higher ability to form biofilms, posing therapeutic challenges.
PATHOGENS AND DISEASE
(2022)
Proceedings Paper
Materials Science, Multidisciplinary
Anil Kumar Pal, Nicholas J. Goddard, Ruchi Gupta
PHOTOSENSITIVE MATERIALS AND THEIR APPLICATIONS
(2020)
Article
Medicine, General & Internal
Ramakrishnan Kalaivani, Pravin Charles, Saranathan, Seetha Kunigal, Kenchappa Prashanth
JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH
(2018)
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
