Article
Biochemistry & Molecular Biology
Denis Mihaela Panaitescu, Sergiu Stoian, Adriana Nicoleta Frone, George Mihai Vlasceanu, Dora Domnica Baciu, Augusta Raluca Gabor, Cristian Andi Nicolae, Valentin Raditoiu, Elvira Alexandrescu, Angela Casarica, Celina Damian, Paul Stanescu
Summary: In this study, oxidized sucrose was used as a crosslinker for aminated bacterial cellulose scaffolds, resulting in three-dimensional cellulose structures with good mechanical properties and high porosity, suitable for soft tissue engineering.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Review
Engineering, Environmental
Xiaosen Pan, Jie Li, Ning Ma, Xiaojun Ma, Meng Gao
Summary: Biohydrogel-based flexible sensors are gaining significant attention due to their applications in personalized mobile equipment, human-machine interface units, wearable medical-healthcare systems, and bionic intelligent robots. Among various biomaterials, bacterial cellulose (BC) stands out due to its low cost, renewability, easy processability, biodegradability, high purity, easy modification and functionalization, as well as appealing mechanical performance. This report provides an overview of the structure-property-application relationships of BC hydrogel and its applications in flexible sensors, including strain, pH, electroactive, and thermal sensors.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Infectious Diseases
Zijun Zhang, Kai Cao, Jiamin Liu, Zhenyu Wei, Xizhan Xu, Qingfeng Liang
Summary: Bacterial keratitis is a common type of infectious keratitis, and the spectrum of pathogenic bacteria and their drug susceptibility varies among different regions. A meta-analysis was conducted to review the global culture rate, distribution, trends, and drug susceptibility of bacterial isolates from bacterial keratitis over the past 20 years. The most common bacteria were Staphylococcus spp., Pseudomonas spp., Streptococcus spp., Corynebacterium spp., and Moraxella spp. The analysis also revealed differences in antibiotic susceptibility among different bacteria types.
Article
Biochemistry & Molecular Biology
Sanosh Kunjalukkal Padmanabhan, Leonardo Lamanna, Marco Friuli, Alessandro Sannino, Christian Demitri, Antonio Licciulli
Summary: In this study, a sodium carboxymethylcellulose (CMC) hydrogel was produced through a bacterial cellulose etherification reaction with chloroacetic acid in an alkaline medium. The synthesized CMC exhibited solubility in water, and FTIR and XRD analyses confirmed the etherification reaction. The alkalinization effect on BC modification was studied, and SEM analysis showed a change in BC microstructure. The optimized CMC could be used to produce ultrapure hydrogel for applications in healthcare and pharmaceutical industry.
Article
Engineering, Biomedical
Samira Aghlara-Fotovat, Elena Musteata, Michael D. Doerfert, Moshe Baruch, Maya Levitan, Jeffrey J. Tabor, Omid Veiseh
Summary: Researchers have discovered that encapsulating bacteria in alginate core-shell particles enhances their survival ability in vivo, enabling them to sense and report disease biomarkers in the gastro-intestinal tract. This study holds promise for the development of next-generation smart therapeutics and non-invasive monitoring of various diseases.
Review
Engineering, Environmental
Aggarapu Chandana, Sarada Prasanna Mallick, Pritam Kumar Dikshit, Bhisham Narayan Singh, Ajay Kumar Sahi
Summary: Bacterial cellulose (BC) has gained major popularity due to its simple production process, non-toxicity, and biocompatibility, and possesses unique properties such as higher crystallinity, larger surface area, and high porosity. BC has broad application prospects in areas such as drug delivery, tissue engineering, and medical sectors.
JOURNAL OF POLYMERS AND THE ENVIRONMENT
(2022)
Article
Engineering, Environmental
Di Wang, Zhiyu Li, Li Yang, Jin Zhang, Yuhui Wei, Quan Feng, Qufu Wei
Summary: Researchers have introduced a novel bacterial cellulose reinforced hydrogel electrolyte for constructing flexible and safe quasi-solid state supercapacitors. The electrolyte exhibits excellent mechanical properties, anti-swelling performance, and high ionic conductivity, particularly in sub-zero temperatures. This work provides insights into the design of strong, antifreezing, anti-swelling, and highly conductive hydrogel electrolytes, paving the way for developing extremely safe wearable storage devices.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Applied
Go Takayama, Tetsuo Kondo
Summary: The study aims to understand the relationship between the network structure and properties of bacterial cellulose (BC) hydrogels, and proposes a method for quantitative evaluation of nanofibril network structure. Various BC hydrogels with different network structures were prepared from seven bacterial strains, and the crosslink densities of the gels were determined quantitatively. Tensile tests showed that the stress-strain curves of BC hydrogels exhibited strain hardening, and the power exponent had a linear relationship with the crosslink density. This provides insights into the structure-property relationships of BC hydrogels for quality control, process optimization, and property prediction.
CARBOHYDRATE POLYMERS
(2023)
Article
Engineering, Environmental
Xudong Zheng, Wen Sun, Ang Li, Yuzhe Zhang, Zhongyu Li
Summary: In this paper, a biocompatible bacterial cellulose-based aerogel was prepared using graphene oxide, polyethylene glycol, and ion imprinting technology for the highly selective adsorption of dysprosium ions. The aerogel showed high stability and repeatability, and exhibited an effective adsorption capacity for dysprosium ions.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2022)
Review
Polymer Science
Sam Swingler, Abhishek Gupta, Hazel Gibson, Marek Kowalczuk, Wayne Heaselgrave, Iza Radecka
Summary: Bacterial cellulose produced by Komagateibacter xylinus has unique properties such as high chemical purity, nano-fibrillar matrix, and crystallinity, making it a promising candidate for various applications including biomedical, potable treatment, nano-filters, and functional applications. Its superior performance compared to other natural or synthetic analogues is attributed to these distinct characteristics, making it an ideal subject for further scientific research in biopolymer development.
Article
Biochemistry & Molecular Biology
Baramee Chanabodeechalermrung, Tanpong Chaiwarit, Sarana Rose Sommano, Pornchai Rachtanapun, Nutthapong Kantrong, Chuda Chittasupho, Pensak Jantrawut
Summary: Composite bacterial cellulose hydrogel with PHMB showed improved physicochemical properties and excellent biocompatibility, demonstrating potential as a dual crosslinked ion-based hydrogel for wound dressing with anti-bacterial activity.
Article
Chemistry, Applied
Zhe Sun, Yudi Kuang, Mehraj Ahmad, Yang Huang, Sha Yin, Farzad Seidi, Sha Wang
Summary: In this study, a bacterial cellulose (BC) derived hydrogel membrane with a double-network (DN) structure and tailored ion transport channels was reported. The fabricated AAM/BC DN hydrogel membrane displayed a unique hierarchical interconnected porous structure and 3D cation transport channels. The results showed that it achieved a maximum power density of 7.63 Wv at a 50-fold salinity gradient under alkaline conditions (pH 11). Additionally, it obtained a power density of 45.5 W·m(-2) through acid-base neutralization reaction, and 28.4 W·m(-2) from a mixed system of paper black liquor wastewater/seawater. The investigation suggested the enormous potential of BC-based nanofluidic membrane in sustainable osmotic energy conversion.
CARBOHYDRATE POLYMERS
(2023)
Article
Materials Science, Paper & Wood
Jianwei Lu, Yangang Jiang, Zihao Wen, Zhengjin Luo, Yufei Qiao, Li Guo
Summary: In this study, highly carboxylated absorption media were fabricated using bacterial cellulose nanofibrous aerogel in combination with citric acid. The resulting absorption media exhibited a highly interconnected open porous structure, hydrophilicity, and a large specific surface area. They also displayed high absorption capacity and fast equilibrium for positively charged proteins, as well as selectivity and acid/alkaline resistance.
Article
Chemistry, Applied
Soledad Roig-Sanchez, Doron Kam, Nanthilde Malandain, Ela Sachyani-Keneth, Oded Shoseyov, Shlomo Magdassi, Anna Laromaine, Anna Roig
Summary: Acrylate hydrogels are potential soft tissue implants, but their weak mechanical properties and dimensional changes in liquids limit their applications. By fabricating double network hydrogels, the mechanical properties and swelling behavior of acrylate hydrogels can be improved.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Physical
Si Meng, Yuyan Zhang, Nihuan Wu, Cheng Peng, ZhiYao Huang, Zhengjie Lin, Cheng Qi, Zhou Liu, Tiantian Kong
Summary: The development of implantable bioelectronics is driven by emerging applications including continuous health monitoring and human-machine interfacing. However, the mechanical mismatch between the implanted bioelectronics and tissues compromises device accuracy and causes interference with tissues. To address this issue, researchers have developed an ultrasoft and biocompatible fiber strain sensor using bacterial cellulose. This fiber possesses stretchability and elastic modulus similar to that of soft tissues, and it demonstrates high sensitivity to tiny tensile force/strain and low cell cytotoxicity. The bacterial cellulose-based sensing fiber shows potential for monitoring subtle motions of organs in implantable bioelectric devices.
Article
Chemistry, Analytical
Mengmeng Guo, Na Luo, Yueling Bai, Zhenggang Xue, Qingmin Hu, Jiaqiang Xu
Summary: A porous heterostructure WO3-C/In2O3 was designed and prepared for a miniature H2 sensor, which showed higher response value, lower operating temperature, fast response-recovery speed, and low limit of detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Feng Hu, Hui Hu, Yuting Li, Xiaohui Wang, Xiaowen Shi
Summary: Arsenic contamination in water bodies is a significant health risk. This study developed a chitosan-catechol modified electrode for rapid and accurate detection of trace amounts of arsenic. The modified electrode demonstrated good detection capability and resistance to ionic interference, making it suitable for in situ detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Yantao Zhang, Qian Liu, Tao Tian, Chunhua Xu, Pengli Yang, Lianju Ma, Yi Hou, Hui Zhou, Yongjun Gan
Summary: In this study, a lysosome-targeting buffering fluorogenic probe (Lyso-BFP) was designed and synthesized, demonstrating excellent photostability, pH specificity, and responsiveness to lysosomal acidification in living cells. The performance of Lyso-BFP in pH sensing was attributed to the inhibition of the photo-induced electron transfer process. Lyso-BFP allowed for wash-free imaging and long-term real-time monitoring of lysosome pH changes based on its off-on fluorescence behavior and buffer strategy.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Wei Cai, Wenbo Sun, Jiayue Wang, Xiaokui Huo, Xudong Cao, Xiangge Tian, Xiaochi Ma, Lei Feng
Summary: In this study, a near-infrared fluorescent probe HCBG was developed for imaging of alpha-GLC. HCBG exhibited excellent selectivity and sensitivity towards alpha-GLC in complex bio-samples, and showed good cell permeability for in situ real-time imaging. Through the high-throughput screening system established by HCBG, a natural alpha-GLC inhibitor was successfully isolated and identified. This study provides a novel fluorescence visualization tool for discovering and exploring the biological functions of diabetes-related gut microbiota, and a high-throughput screening approach for alpha-GLC inhibitor.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Trey W. Pittman, Xi Zhang, Chamindie Punyadeera, Charles S. Henry
Summary: Heart failure is a growing epidemic and a significant clinical and public health problem. Researchers have developed a portable and affordable diagnostic device for heart failure that can be used at the point-of-care, providing a valid alternative to current diagnostics approaches.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Anders O. Tjell, Barbara Jud, Roland Schaller-Ammann, Torsten Mayr
Summary: An optical hydrogen peroxide sensor based on catalytic degradation and the detection of produced oxygen is presented. The sensor offers higher resolution and better sensitivity at lower H2O2 concentrations. By removing O2 from the sample solution, a more sensitive O2 sensor can be used for measurement. The sensor has been successfully applied in a flow-through cell to measure H2O2 concentration in different flow rates.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Seong Jae Kim, Ji-hun Jeong, Gaabhin Ryu, Yoon Sick Eom, Sanha Kim
Summary: Surface-enhanced Raman spectroscopy (SERS) is a high-sensitivity, label-free detection method with various analytical applications. Researchers have developed a hydrophobic SERS substrate based on engineered carbon nanotube arrays (CNT-SERS) and studied the role of structural design at both micro and nanoscales. The substrate demonstrated controlled self-enrichment capability and enhanced sensitivity, with a significant increase in the SERS signal. The study also proposed a theoretical model and a concentration strategy inspired by plants for analyte deposition on microarrays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Dan Zhao, Renjun Jiang, Xiaoqiang Liu, Subbiah Alwarappan
Summary: In this study, a novel ternary composite material was constructed by assembling cerium vanadate nanorods on reduced graphene oxide-microcrystalline cellulose nanosheets, and it was used for real-time monitoring of the concentration of superoxide anions in vivo. The ternary composite showed excellent conductivity, large surface area, and abundant active sites, leading to a wider linear range, high sensitivity, low detection limit, and fast response time for superoxide anion detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Tengfei Wang, Liwen Wang, Guang Wu, Dating Tian
Summary: In this study, a covalent organic framework material TaTp-COF with porous and uniform spheres was successfully prepared via hydrothermal reaction, and it was found to significantly enhance the aggregation-induced emission (AIE) of berberine. The unique emission properties of berberine on TaTp-COF were studied and utilized for the sensitive detection of berberine.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Lin Li, Yilei Ding, Lei Xu, Shuoran Chen, Guoliang Dai, Pengju Han, Lixin Lu, Changqing Ye, Yanlin Song
Summary: In this study, a novel TTI based on a ratiometric fluorescent nanosensor is designed, which has the advantages of high accuracy and low cost. Experimental and theoretical investigations confirm its pH responsiveness and demonstrate its good sensitivity and reliability. By monitoring the total volatile basic nitrogen, this TTI can accurately predict food spoilage and can be adaptively modified for different types of food. The TTI based on this nanosensor enables visual monitoring of food quality.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Fangju Chen, Xueting Wang, Wei Chen, Chenwen Shao, Yong Qian
Summary: Lung cancer is the second most common malignant tumor worldwide. Drug resistance in lung cancer leads to treatment failure and recurrence in majority of patients. This study developed a fluorescent prodrug that can be activated in cancer cells to release drugs, and its signal can be tracked by imaging. It shows a unique autophagy-driven ferroptosis effect, indicating its potential for targeting drug-resistant cancer cells.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Weichao Li, Qiming Yuan, Zhangcheng Xia, Xiaoxue Ma, Lifang He, Ling Jin, Xiangfeng Chu, Kui Zhang
Summary: This study developed a high-performance gas sensor for formaldehyde detection by modifying ZnSnO3 with ZnO QDs and SnO2 QDs. The modified sensor showed improved sensing response and lower working temperature. The presence of ZnO QDs formed rich heterojunctions, increased surface area, and provided oxygen deficiency for formaldehyde sensing reaction, thus enhancing the sensor performance. This research provides an alternative method to enhance the sensing properties of MOS by QDs modification.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Joung-Il Moon, Eun Jung Choi, Younju Joung, Jin-Woo Oh, Sang-Woo Joo, Jaebum Choo
Summary: A novel nanoplasmonic substrate was developed for biomedical applications, which showed strong hot spots for detecting biomarkers at low concentrations. The substrate, called AuNPs@M13, was made by immobilizing 60 nm gold nanoparticles onto the surface of an M13 bacteriophage scaffold. It demonstrated higher sensitivity and lower limit of detection compared to commercially available assays.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Ning Li, Ya Zhang, Ying Xu, Xiaofang Liu, Jian Chen, Mei Yang, Changjun Hou, Danqun Huo
Summary: The molecular subtype of breast cancer guides treatment and drug selection. Invasive tests can promote cancer cell metastasis, so the development of high-performance, low-cost diagnostic tools for cancer prognosis is crucial. Liquid biopsy techniques enable noninvasive, real-time, dynamic, multicomponent, quantitative, and long-term observations at the cellular, genetic, and molecular levels. A Cu-Zr metal-organic framework (MOF) nanoenzyme with monatomic Cu attachment has been synthesized and proven to have high catalytic performance. The sensor constructed using this nanoenzyme shows potential for accurate classification of breast cancer serum samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
Article
Chemistry, Analytical
Jeongmin Kim, Hyemin Kim, Seunghyun Park, Hyeonaug Hong, Yong Jae Kim, Jiyong Lee, Jaeho Kim, Seung-Woo Cho, Wonhyoung Ryu
Summary: This study presents a method to fabricate independently functioning microneedle (MN) electrodes with narrow intervals for high precision electrochemical sensing. The optimized mixture of photocurable polymer and single-wall carbon nanotubes was used to mold single composite MNs, which were then attached to pre-patterned electrodes. Plasma etching and electropolymerization were performed to enhance the electrochemical activity, and Prussian blue and glucose oxidase were electrodeposited on the MNs for glucose detection. The MN electrodes showed good sensitivity and linearity, and the feasibility of glucose detection was demonstrated in an in vivo mouse study.
SENSORS AND ACTUATORS B-CHEMICAL
(2024)
