Fisetin Inhibits Human Melanoma Cell Invasion through Promotion of Mesenchymal to Epithelial Transition and by Targeting MAPK and NFκB Signaling Pathways

Fisetin inhibits growth, induces G2/M arrest and apoptosis of human epidermoid carcinoma A431 cells: role of mitochondrial membrane potential disruption and consequent caspases activation

(2013) Harish C. Pal et al.   EXPERIMENTAL DERMATOLOGY

The inclusion complex of 4-hydroxynonenal with a polymeric derivative of β-cyclodextrin enhances the antitumoral efficacy of the aldehyde in several tumor cell lines and in a three-dimensional human melanoma model

(2013) Stefania Pizzimenti et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Polyphenol Fisetin Protects Bone by Repressing NF-κB and MKP-1-Dependent Signaling Pathways in Osteoclasts

(2013) Laurent Léotoing et al.   PLoS One

TWIST1 Is an ERK1/2 Effector That Promotes Invasion and Regulates MMP-1 Expression in Human Melanoma Cells

(2012) M. B. Weiss et al.   CANCER RESEARCH

Fisetin, a bioactive flavonol, attenuates allergic airway inflammation through negative regulation of NF-κB

(2012) Fera Y. Goh et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inhibition of c-Jun N-terminal kinase and nuclear factor κ B pathways mediates fisetin-exerted anti-inflammatory activity in lipopolysccharide-treated RAW264.7 cells

(2012) Sun-Chae Kim et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Acquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK Inhibition

(2012) Kavitha Gowrishankar et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Oncogenic B-RAFV600E Signaling Induces the T-Box3 Transcriptional Repressor to Repress E-Cadherin and Enhance Melanoma Cell Invasion

(2012) Suzanah C. Boyd et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Improved Survival with MEK Inhibition in BRAF-Mutated Melanoma

(2012) Keith T. Flaherty et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibition of Human Melanoma Cell Growth by the Dietary Flavonoid Fisetin Is Associated with Disruption of Wnt/β-Catenin Signaling and Decreased Mitf Levels

(2011) Deeba N. Syed et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Progression of BRAF-induced thyroid cancer is associated with epithelial–mesenchymal transition requiring concomitant MAP kinase and TGFβ signaling

(2011) J A Knauf et al.   ONCOGENE

Raf kinases in cancer–roles and therapeutic opportunities

(2011) G Maurer et al.   ONCOGENE

Grape Seed Proanthocyanidins Inhibit Melanoma Cell Invasiveness by Reduction of PGE2 Synthesis and Reversal of Epithelial-to-Mesenchymal Transition

(2011) Mudit Vaid et al.   PLoS One

Green Tea Catechins Reduce Invasive Potential of Human Melanoma Cells by Targeting COX-2, PGE2 Receptors and Epithelial-to-Mesenchymal Transition

(2011) Tripti Singh et al.   PLoS One

Fisetin induces autophagic cell death through suppression of mTOR signaling pathway in prostate cancer cells

(2010) Y. Suh et al.   CARCINOGENESIS

Genetic and morphologic features for melanoma classification

(2010) Sigrid M. C. Broekaert et al.   Pigment Cell & Melanoma Research

B-RafV600E and thrombospondin-1 promote thyroid cancer progression

(2010) C. Nucera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epithelial-Mesenchymal Transitions in Development and Disease

(2009) Jean Paul Thiery et al.   CELL

Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-κB

(2009) Imtiyaz Murtaza et al.   INTERNATIONAL JOURNAL OF CANCER

NF-κB Inhibition through Proteasome Inhibition or IKKβ Blockade Increases the Susceptibility of Melanoma Cells to Cytostatic Treatment through Distinct Pathways

(2009) Katharina Amschler et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Prognostic Significance of Cadherin-Based Adhesion Molecules in Cutaneous Malignant Melanoma

(2008) G. M. Kreizenbeck et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

A Novel Dietary Flavonoid Fisetin Inhibits Androgen Receptor Signaling and Tumor Growth in Athymic Nude Mice

(2008) N. Khan et al.   CANCER RESEARCH

Epithelial-Mesenchymal Transition in Breast Cancer Relates to the Basal-like Phenotype

(2008) D. Sarrio et al.   CANCER RESEARCH

A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF- B-signaling pathways

(2008) Y. Suh et al.   CARCINOGENESIS

Fisetin, a novel dietary flavonoid, causes apoptosis and cell cycle arrest in human prostate cancer LNCaP cells

(2008) Naghma Khan et al.   CARCINOGENESIS

Snail-associated epithelial–mesenchymal transition promotes oesophageal squamous cell carcinoma motility and progression

(2008) Y Usami et al.   JOURNAL OF PATHOLOGY

Improving Melanoma Classification by Integrating Genetic and Morphologic Features

(2008) Amaya Viros et al.   PLOS MEDICINE

Defective Cell Cycle Checkpoint Functions in Melanoma Are Associated with Altered Patterns of Gene Expression

(2007) William K. Kaufmann et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY