Article
Multidisciplinary Sciences
Xiaotu Ma, Xiaolong Liang, Meinan Yao, Yu Gao, Qi Luo, Xiaoda Li, Yue Yu, Yining Sun, Miffy H. Y. Cheng, Juan Chen, Gang Zheng, Jiyun Shi, Fan Wang
Summary: This study develops a novel nanoplatform, Gd-NTs, that improves the radiosensitization effects of Gd-coordinated Texaphyrin and inhibits tumor recurrence by relieving tumor hypoxia through loading myoglobulin.
NATURE COMMUNICATIONS
(2023)
Review
Radiology, Nuclear Medicine & Medical Imaging
Yang Sheng, Jiahan Zhang, Yaorong Ge, Xinyi Li, Wentao Wang, Hunter Stephens, Fang-Fang Yin, Qiuwen Wu, Q. Jackie Wu
Summary: Artificial Intelligence (AI) refers to methods that improve and automate difficult tasks by capturing and applying relevant knowledge systematically. In the context of radiation treatment planning, multiple AI approaches can be used to enhance planning quality and efficiency.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2021)
Review
Oncology
Antonella Castellano, Michele Bailo, Francesco Cicone, Luciano Carideo, Natale Quartuccio, Pietro Mortini, Andrea Falini, Giuseppe Lucio Cascini, Giuseppe Minniti
Summary: This review focuses on advanced MRI and PET imaging techniques that have promise as a complement to conventional MRI for radiation treatment planning of gliomas. Advanced MRI techniques provide additional metabolic, structural, and hemodynamic information for target delineation, while PET techniques offer potential for biological characterization of gliomas. The combination of these advanced imaging modalities may improve accuracy in target delineation and reduce treatment-related toxicity in radiation therapy for cerebral gliomas.
Review
Engineering, Biomedical
Lanyu Xu, Simeng Zhu, Ning Wen
Summary: This paper introduces the application of reinforcement learning and deep reinforcement learning (DRL) in medical image analysis and radiation treatment planning. By learning the interactions and reward distribution, DRL algorithms address the challenges of scarce and heterogeneous medical image data, improving deep learning models in clinical applications.
PHYSICS IN MEDICINE AND BIOLOGY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Marco Schwarz, Erik Traneus, Sairos Safai, Anna Kolano, Steven van de Water
Summary: The Flash effect, which increases radioresistence of healthy tissues when irradiated at high doses, is being investigated to improve the therapeutic ratio of radiotherapy treatments. Patient-specific balance between dose distribution properties is necessary for maximizing the benefits of Flash in clinical applications. Proton therapy techniques have shown potential in generating Flash dose distributions, with parameters such as beam current, Flash dose rate threshold, and dose rate definition playing key roles in the amount of Flash dose in normal tissue. Systematic estimation of Flash impact on different patient anatomies and treatment protocols requires Flash-specific treatment planning features. Evaluation tools and optimization strategies are needed to take full advantage of the potential benefits of the Flash effect.
Article
Radiology, Nuclear Medicine & Medical Imaging
Shengzhen Tao, Hao Gong, Gregory Michalak, Cynthia McCollough, Shuai Leng, Yanle Hu
Summary: The study evaluated the accuracy of scaled CT numbers using an artificial 120 kV reconstruction technique. Results showed that the technique reduced the dependence on tube potential and improved the accuracy of scaled CT numbers compared to conventional reconstruction methods.
Article
Chemistry, Inorganic & Nuclear
Jun Yang, Peiling Dai, Meng Li, Man Tang, Qi Wu, Shujuan Liu, Qiang Zhao, Kenneth Yin Zhang
Summary: Fluorescent/phosphorescent dual-emissive polymers have been widely used for self-calibrating oxygen sensing in cells. In this study, a lifetime-ratiometric luminescent polymeric probe was developed, which achieved spectral separation based on the difference in the excited-state lifetimes of the fluorophore and phosphor. The probe showed promising results for quantitative oxygen sensing and mapping in living cells.
DALTON TRANSACTIONS
(2022)
Article
Engineering, Multidisciplinary
Md Samsuzzaman, Md Siam Talukder, Abdulrahman Alqahtani, Abdullah G. Alharbi, Rezaul Azim, Mohamed S. Soliman, Mohammad Tariqul Islam
Summary: Medical microwave imaging (MWI) research, especially in the early detection of brain tumors, has gained increasing attention in recent decades. This article presents a new simple patch antenna for MWI, designed with a low-cost FR4-epoxy substrate. The antenna achieves a wide impedance bandwidth and high efficiency, as confirmed by measurements and simulations. Additionally, a 3D-electromagnetic CST simulator was utilized to analyze the antenna's behavior in a realistic model, demonstrating its practical utility in MWI applications.
ALEXANDRIA ENGINEERING JOURNAL
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Carolin Stapper, Stefan Gerlach, Theresa Hofmann, Christoph Fueweger, Alexander Schlaefer
Summary: This study aims to investigate an improved approach for radiosurgery treatment planning using the ZAP-X (R) system. The proposed method automatically selects the locations of isocenters and demonstrates comparable plans to those produced by expert selected isocenters. This approach can reduce the effort and time required for treatment planning in gyroscopic radiosurgery.
Article
Crystallography
Rubi Gul, John Stuart McCloy, Magesh Murugesan, Benjamin Montag, Jasdeep Singh
Summary: In this study, Cl-doped CdTe single crystals were grown under tellurium excess conditions, and the effects of tellurium excess on detector performance and resistivity were investigated. The results showed that tellurium excess caused additional nucleation and decreased grain size, but also improved electrical transport properties. Furthermore, Cl-doped CdTe crystals grown under 15% tellurium excess exhibited better response to gamma rays and alpha particles, as well as high electron and hole mobilities.
Article
Radiology, Nuclear Medicine & Medical Imaging
Norikazu Koori, Hiroki Kamekawa, Nanami Mukawa, Hiraku Fuse, Shin Miyakawa, Kenji Yasue, Masato Takahashi, Masanori Yamada, Atsushi Henmi, Toshifumi Kusumoto, Kazuma Kurata
Summary: This study investigates the relationship between imaging parameters and image distortion when using G-frames in MRI. Image distortion is measured by changing RF pulse mode, gradient mode, asymmetric echo, and bandwidth. The study finds that image distortion increases in different modes and suggests adjusting parameters to minimize distortion.
JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS
(2023)
Article
Materials Science, Biomaterials
Shuying Li, Wenjie Sun, Yuan Luo, Yanping Gao, Xueping Jiang, Cheng Yuan, Linzhi Han, Kuo Cao, Yan Gong, Conghua Xie
Summary: A novel hollow PtCo nanosphere-based radiosensitizer is proposed with advantages including higher radiation absorption, dual catalase-like enzymatic activity converting H2O2 to O2 efficiently, and a large specific surface area amplifying catalytic reaction of H2O2 to induce reactive oxygen species and cancer cell apoptosis upon combination with radiation. Both in vivo and in vitro studies demonstrate the significant inhibition of tumor growth and relief of tumor hypoxia with good biocompatibility and biosafety, presenting a simple but multifunctional radiosensitizer for enhancing radiotherapy.
JOURNAL OF MATERIALS CHEMISTRY B
(2021)
Article
Chemistry, Multidisciplinary
Zhen-Wei Han, Ke-Fei Song, Shi-Jie Liu, Quan-Feng Guo, Guang-Xing Ding, Ling-Ping He, Cheng-Wei Li, Hong-Ji Zhang, Yang Liu, Bo Chen
Summary: Concerns over space radiation's impact on spacecraft and their instruments has led to the need for effective protection. However, excessive protection can increase costs and difficulty, making lightweight shielding crucial. The interference of charged particles on photon-counting imaging detectors in real space orbits was observed, and a shielding ring was proposed to address this issue. Additionally, a local protection structure with an increased outer edge was suggested for electronics, resulting in an omnidirectional spatial shielding thickness on the PCB surface.
APPLIED SCIENCES-BASEL
(2023)
Review
Chemistry, Physical
Jiale Chai, Jintu Fan
Summary: This article reviews materials with the function of solar and thermal radiation modulation (STRMMs) in three categories: solar radiation modulation, thermal radiation modulation, and synergetic solar and thermal radiation modulation. It compares and elaborates their working principles, representative examples, potential applications, and future perspectives.
ADVANCED ENERGY MATERIALS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Eenas A. Omari, Ying Zhang, Ergun Ahunbay, Eric Paulson, Asma Amjad, Xinfeng Chen, Ying Liang, X. Allen Li
Summary: This article reviews the current status of MpMRI in radiation therapy planning, including common sequences, preprocessing strategies, and image registration techniques. It also discusses automatic segmentation and deep learning techniques for organ delineation, as well as considerations for MRI-only planning in MRI-guided adaptive radiotherapy.
