HIV-1 Reservoirs in Breast Milk and Challenges to Elimination of Breast-Feeding Transmission of HIV-1

The potential impact of CD4+ T cell activation and enhanced Th1/Th2 cytokine ratio on HIV-1 secretion in the lungs of individuals with advanced AIDS and active pulmonary infection

(2011) Pierre-Alain Rubbo et al.   CLINICAL IMMUNOLOGY

Cumulative Exposure to Cell-Free HIV in Breast Milk, Rather Than Feeding Pattern per se, Identifies Postnatally Infected Infants

(2011) Dorine Neveu et al.   CLINICAL INFECTIOUS DISEASES

Initiation of Antiretroviral Treatment in Women After Delivery Can Induce Multiclass Drug Resistance in Breastfeeding HIV-Infected Infants

(2011) J. Fogel et al.   CLINICAL INFECTIOUS DISEASES

Efficacy and safety of an extended nevirapine regimen in infant children of breastfeeding mothers with HIV-1 infection for prevention of postnatal HIV-1 transmission (HPTN 046): a randomised, double-blind, placebo-controlled trial

(2011) Hoosen M Coovadia et al.   LANCET

Triple antiretroviral compared with zidovudine and single-dose nevirapine prophylaxis during pregnancy and breastfeeding for prevention of mother-to-child transmission of HIV-1 (Kesho Bora study): a randomised controlled trial

(2011)   LANCET INFECTIOUS DISEASES

CD4+ T cells spontaneously producing human immunodeficiency virus type I in breast milk from women with or without antiretroviral drugs

(2011) Diane Valea et al.   Retrovirology

Genital HIV-1 RNA Predicts Risk of Heterosexual HIV-1 Transmission

(2011) J. M. Baeten et al.   Science Translational Medicine

Triple-Antiretroviral Prophylaxis to Prevent Mother-To-Child HIV Transmission through Breastfeeding—The Kisumu Breastfeeding Study, Kenya: A Clinical Trial

(2011) Timothy K. Thomas et al.   PLOS MEDICINE

HIV-1 Drug Resistance Emergence among Breastfeeding Infants Born to HIV-Infected Mothers during a Single-Arm Trial of Triple-Antiretroviral Prophylaxis for Prevention of Mother-To-Child Transmission: A Secondary Analysis

(2011) Clement Zeh et al.   PLOS MEDICINE

The Genotype of Early-Transmitting HIV gp120s Promotes α4β7 –Reactivity, Revealing α4β7+/CD4+ T cells As Key Targets in Mucosal Transmission

(2011) Fatima Nawaz et al.   PLoS Pathogens

Pharmacokinetics and Disposition of Rilpivirine (TMC278) Nanosuspension as a Long-Acting Injectable Antiretroviral Formulation

(2010) G. van 't Klooster et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Transformation of breast milk macrophages by HTLV-I: implications for HTLV-I transmission via breastfeeding

(2010) Hodaka Takeuchi et al.   BIOMEDICAL RESEARCH-TOKYO

APOBEC3 Proteins Expressed in Mammary Epithelial Cells Are Packaged into Retroviruses and Can Restrict Transmission of Milk-Borne Virions

(2010) Chioma M. Okeoma et al.   Cell Host & Microbe

Associations between Breast Milk Viral Load, Mastitis, Exclusive Breast‐Feeding, and Postnatal Transmission of HIV

(2010) Kevin M. Lunney et al.   CLINICAL INFECTIOUS DISEASES

Inhibition of DC-SIGN-mediated transmission of human immunodeficiency virus type 1 by Toll-like receptor 3 signalling in breast milk macrophages

(2010) Yukie Yagi et al.   IMMUNOLOGY

Association between Breast Milk Erythropoietin and Reduced Risk of Mother‐to‐Child Transmission of HIV

(2010) Joanne E. Arsenault et al.   JOURNAL OF INFECTIOUS DISEASES

The Mucosal Immune System and Its Integration with the Mammary Glands

(2010) Per Brandtzaeg   JOURNAL OF PEDIATRICS

Breast Milk as the Gold Standard for Protective Nutrients

(2010) Allan Walker   JOURNAL OF PEDIATRICS

Genetic Analyses of HIV-1envSequences Demonstrate Limited Compartmentalization in Breast Milk and Suggest Viral Replication within the Breast That Increases with Mastitis

(2010) Soren Gantt et al.   JOURNAL OF VIROLOGY

Primary Human Mammary Epithelial Cells Endocytose HIV-1 and Facilitate Viral Infection of CD4+T Lymphocytes

(2010) Stephanie M. Dorosko et al.   JOURNAL OF VIROLOGY

Maternal or Infant Antiretroviral Drugs to Reduce HIV-1 Transmission

(2010) Charles S. Chasela et al.   NEW ENGLAND JOURNAL OF MEDICINE

Antiretroviral Regimens in Pregnancy and Breast-Feeding in Botswana

(2010) R.L. Shapiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

Unravelling the Mystery of Stem/Progenitor Cells in Human Breast Milk

(2010) Yiping Fan et al.   PLoS One

HIV-1 persists in breast milk cells despite antiretroviral treatment to prevent mother-to-child transmission

(2009) Dara A Lehman et al.   AIDS

Cytomegalovirus and Epstein–Barr virus in breast milk are associated with HIV-1 shedding but not with mastitis

(2009) Soren Gantt et al.   AIDS

Pharmacokinetics, safety and efficacy of lopinavir/ritonavir in infants less than 6 months of age: 24 week results

(2009) Ellen G Chadwick et al.   AIDS

Breastfeeding with maternal antiretroviral therapy or formula feeding to prevent HIV postnatal mother-to-child transmission in Rwanda

(2009) Cécile Alexandra Peltier et al.   AIDS

Universal Antiretroviral Therapy for Pregnant and Breast‐Feeding HIV‐1–Infected Women: Towards the Elimination of Mother‐to‐Child Transmission of HIV‐1 in Resource‐Limited Settings

(2009) Renaud Becquet et al.   CLINICAL INFECTIOUS DISEASES

Prevention of Mother-to-Child Transmission of HIV-1 Through Breast-Feeding by Treating Infants Prophylactically With Lamivudine in Dar es Salaam, Tanzania

(2009) Charles Kilewo et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Innate Factors in Human Breast Milk Inhibit Cell-Free HIV-1 but Not Cell-Associated HIV-1 Infection of CD4+ Cells

(2009) Magdalena A Lyimo et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Human Milk-Derived B Cells: A Highly Activated Switched Memory Cell Population Primed to Secrete Antibodies

(2009) E. Tuaillon et al.   JOURNAL OF IMMUNOLOGY

A Case Series of 104 Women Infected with HIV‐1 via Blood Transfusion Postnatally: High Rate of HIV‐1 Transmission to Infants through Breast‐Feeding

(2009) Ke Liang et al.   JOURNAL OF INFECTIOUS DISEASES

High Concentrations of Interleukin 15 in Breast Milk Are Associated with Protection against Postnatal HIV Transmission

(2009) Jan Walter et al.   JOURNAL OF INFECTIOUS DISEASES

Preservation of Memory CD4+T Lymphocytes in Breast Milk of Lactating Rhesus Monkeys during Acute Simian Immunodeficiency Virus Infection

(2009) Sallie R. Permar et al.   JOURNAL OF INFECTIOUS DISEASES

Simultaneous Cell-to-Cell Transmission of Human Immunodeficiency Virus to Multiple Targets through Polysynapses

(2009) D. Rudnicka et al.   JOURNAL OF VIROLOGY

MUC1 in human milk blocks transmission of human immunodeficiency virus from dendritic cells to T cells

(2009) Eirikur Saeland et al.   MOLECULAR IMMUNOLOGY

The integrin  4 7 forms a complex with cell-surface CD4 and defines a T-cell subset that is highly susceptible to infection by HIV-1

(2009) C. Cicala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vivo-activated CD103+CD4+ regulatory T cells ameliorate ongoing chronic graft-versus-host disease

(2008) D. Zhao et al.   BLOOD

Tunneling nanotubes (TNT) are induced by HIV-infection of macrophages: A potential mechanism for intercellular HIV trafficking

(2008) E.A. Eugenin et al.   CELLULAR IMMUNOLOGY

Extended-dose nevirapine to 6 weeks of age for infants to prevent HIV transmission via breastfeeding in Ethiopia, India, and Uganda: an analysis of three randomised controlled trials

(2008)   LANCET

Asymmetric division of activated latently infected cells may explain the decay kinetics of the HIV-1 latent reservoir and intermittent viral blips

(2008) Libin Rong et al.   MATHEMATICAL BIOSCIENCES

Membrane nanotubes physically connect T cells over long distances presenting a novel route for HIV-1 transmission

(2008) Stefanie Sowinski et al.   NATURE CELL BIOLOGY

Early Antiretroviral Therapy and Mortality among HIV-Infected Infants

(2008) Avy Violari et al.   NEW ENGLAND JOURNAL OF MEDICINE

Extended Antiretroviral Prophylaxis to Reduce Breast-Milk HIV-1 Transmission

(2008) Newton I. Kumwenda et al.   NEW ENGLAND JOURNAL OF MEDICINE

Studies on Antiretroviral Drug Concentrations in Breast Milk: Validation of a Liquid Chromatography-Tandem Mass Spectrometric Method for the Determination of 7 Anti-Human Immunodeficiency Virus Medications

(2008) Naser L Rezk et al.   THERAPEUTIC DRUG MONITORING