Voltage-gated Na+ Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling

Lidocaine Preferentially Inhibits the Function of Purinergic P2X7 Receptors Expressed in Xenopus Oocytes

(2015) Dan Okura et al.   ANESTHESIA AND ANALGESIA

Understanding the roles of the P2X7 receptor in solid tumour progression and therapeutic perspectives

(2015) Sébastien Roger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The sodium channel-blocking antiepileptic drug phenytoin inhibits breast tumour growth and metastasis

(2015) Michaela Nelson et al.   Molecular Cancer

Potent inhibition by ropivacaine of metastatic colon cancer SW620 cell invasion and Na V 1.5 channel function

(2014) D.T. Baptista-Hon et al.   BRITISH JOURNAL OF ANAESTHESIA

Ranolazine inhibits NaV1.5-mediated breast cancer cell invasiveness and lung colonization

(2014) Virginie Driffort et al.   Molecular Cancer

Transient domoic acid excitotoxicity increases BDNF expression and activates both MEK- and PKA-dependent neurogenesis in organotypic hippocampal slices

(2013) Anabel Pérez-Gómez et al.   BMC NEUROSCIENCE

NaV1.5 Na+ channels allosterically regulate the NHE-1 exchanger and promote the activity of breast cancer cell invadopodia

(2013) L. Brisson et al.   JOURNAL OF CELL SCIENCE

Functional expression of the voltage-gated Na+-channel Nav1.7 is necessary for EGF-mediated invasion in human non-small cell lung cancer cells

(2013) T. M. Campbell et al.   JOURNAL OF CELL SCIENCE

Membrane potential and cancer progression

(2013) Ming Yang et al.   Frontiers in Physiology

ERK1/2 MAP kinases: Structure, function, and regulation

(2012) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Angiogenic Functions of Voltage-gated Na+Channels in Human Endothelial Cells

(2011) Petros Andrikopoulos et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Voltage-Gated Na+ Channel SCN5A Is a Key Regulator of a Gene Transcriptional Network That Controls Colon Cancer Invasion

(2010) C. D. House et al.   CANCER RESEARCH

Piceatannol induces Fas and FasL up-regulation in human leukemia U937 cells via Ca2+/p38α MAPK-mediated activation of c-Jun and ATF-2 pathways

(2010) Wen-Hsin Liu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Semaphorin 3E Initiates Antiangiogenic Signaling through Plexin D1 by Regulating Arf6 and R-Ras

(2010) A. Sakurai et al.   MOLECULAR AND CELLULAR BIOLOGY

NaV1.5 enhances breast cancer cell invasiveness by increasing NHE1-dependent H+ efflux in caveolae

(2010) L Brisson et al.   ONCOGENE

Actions of veratridine on tetrodotoxin-sensitive voltage-gated Na+currents, NaV1.6, in murine vas deferens myocytes

(2009) Hai-Lei Zhu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Activation of Rap1 Promotes Prostate Cancer Metastasis

(2009) C. L. Bailey et al.   CANCER RESEARCH

Using Lidocaine and Benzocaine to Link Sodium Channel Molecular Conformations to State-Dependent Antiarrhythmic Drug Affinity

(2009) Dorothy A. Hanck et al.   CIRCULATION RESEARCH

Molecular pharmacology of voltage-gated sodium channel expression in metastatic disease: Clinical potential of neonatal Nav1.5 in breast cancer

(2009) Rustem Onkal et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Voltage-gated Sodium Channel Activity Promotes Cysteine Cathepsin-dependent Invasiveness and Colony Growth of Human Cancer Cells

(2009) Ludovic Gillet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of Podosome Formation in Macrophages by a Splice Variant of the Sodium ChannelSCN8A

(2009) Michael D. Carrithers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dynamic changes in Rap1 activity are required for cell retraction and spreading during mitosis

(2009) V. T. Dao et al.   JOURNAL OF CELL SCIENCE