The C-Terminal SH3 Domain Contributes to the Intramolecular Inhibition of Vav Family Proteins

Chronic Sympathoexcitation through Loss of Vav3, a Rac1 Activator, Results in Divergent Effects on Metabolic Syndrome and Obesity Depending on Diet

(2013) Mauricio Menacho-Márquez et al.   Cell Metabolism

Pak and Rac GTPases promote oncogenic KIT–induced neoplasms

(2013) Holly Martin et al.   JOURNAL OF CLINICAL INVESTIGATION

The Rho Exchange Factors Vav2 and Vav3 Favor Skin Tumor Initiation and Promotion by Engaging Extracellular Signaling Loops

(2013) Mauricio Menacho-Márquez et al.   PLOS BIOLOGY

Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival

(2012) K. H. Chang et al.   BLOOD

Mechanism and function of Vav1 localisation in TCR signalling

(2012) Olga Ksionda et al.   JOURNAL OF CELL SCIENCE

The Rho Exchange Factors Vav2 and Vav3 Control a Lung Metastasis-Specific Transcriptional Program in Breast Cancer Cells

(2012) C. Citterio et al.   Science Signaling

Coronin 1A promotes a cytoskeletal-based feedback loop that facilitates Rac1 translocation and activation

(2011) Antonio Castro-Castro et al.   EMBO JOURNAL

Essential Role for Vav Guanine Nucleotide Exchange Factors in Brain-Derived Neurotrophic Factor-Induced Dendritic Spine Growth and Synapse Plasticity

(2011) C. F. Hale et al.   JOURNAL OF NEUROSCIENCE

Structural and Energetic Mechanisms of Cooperative Autoinhibition and Activation of Vav1

(2010) Bingke Yu et al.   CELL

Vav3-deficient Mice Exhibit a Transient Delay in Cerebellar Development

(2010) Celia Quevedo et al.   MOLECULAR BIOLOGY OF THE CELL

Vav3 Is Involved in GABAergic Axon Guidance Events Important for the Proper Function of Brainstem Neurons Controlling Cardiovascular, Respiratory, and Renal Parameters

(2010) Vincent Sauzeau et al.   MOLECULAR BIOLOGY OF THE CELL

The Minimal Autoinhibited Unit of the Guanine Nucleotide Exchange Factor Intersectin

(2010) K. Farid Ahmad et al.   PLoS One

Autoinhibition of GEF activity in intersectin 1 is mediated by the short SH3-DH domain linker

(2010) Carsten Kintscher et al.   PROTEIN SCIENCE

The Rho/Rac exchange factor Vav2 controls nitric oxide–dependent responses in mouse vascular smooth muscle cells

(2009) Vincent Sauzeau et al.   JOURNAL OF CLINICAL INVESTIGATION

Protein structure prediction on the Web: a case study using the Phyre server

(2009) Lawrence A Kelley et al.   Nature Protocols

A Role for VAV1 in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

(2009) M. Jagodic et al.   Science Translational Medicine

Role of the C-Terminal SH3 Domain and N-Terminal Tyrosine Phosphorylation in Regulation of Tim and Related Dbl-Family Proteins†

(2008) Marielle E. Yohe et al.   BIOCHEMISTRY

Crucial structural role for the PH and C1 domains of the Vav1 exchange factor

(2008) Jonathan Rapley et al.   EMBO REPORTS

Mechanistic Analysis of the Amplification and Diversification Events Induced by Vav Proteins in B-lymphocytes

(2008) María J. Caloca et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of Guanine Nucleotide Exchange Mediated by the T-Cell Essential Vav1

(2008) Jill E. Chrencik et al.   JOURNAL OF MOLECULAR BIOLOGY