New tricks for an old fox: Impact of TGF  on the DNA damage response and genomic stability

Trimodal Glioblastoma Treatment Consisting of Concurrent Radiotherapy, Temozolomide, and the Novel TGF-β Receptor I Kinase Inhibitor LY2109761

(2015) Mengxian Zhang et al.   NEOPLASIA

Smad7 foci are present in micronuclei induced by heavy particle radiation

(2013) Minli Wang et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of 53BP1 in the Regulation of DNA Double-Strand Break Repair Pathway Choice

(2013) Arun Gupta et al.   RADIATION RESEARCH

Tumors as Organs: Biologically Augmenting Radiation Therapy by Inhibiting Transforming Growth Factor β Activity in Carcinomas

(2013) Shisuo Du et al.   SEMINARS IN RADIATION ONCOLOGY

Resistance of Glioblastoma-Initiating Cells to Radiation Mediated by the Tumor Microenvironment Can Be Abolished by Inhibiting Transforming Growth Factor-β

(2012) Matthew E. Hardee et al.   CANCER RESEARCH

Recognition, signaling, and repair of DNA double-strand breaks produced by ionizing radiation in mammalian cells: The molecular choreography

(2012) Larry H. Thompson   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Novel Smad proteins localize to IR-induced double-strand breaks: interplay between TGFβ and ATM pathways

(2012) Minli Wang et al.   NUCLEIC ACIDS RESEARCH

Blockade of TGF-  Signaling by the TGF R-I Kinase Inhibitor LY2109761 Enhances Radiation Response and Prolongs Survival in Glioblastoma

(2011) M. Zhang et al.   CANCER RESEARCH

TGF 1 Inhibition Increases the Radiosensitivity of Breast Cancer Cells In Vitro and Promotes Tumor Control by Radiation In Vivo

(2011) F. Bouquet et al.   CLINICAL CANCER RESEARCH

Irradiation induced foci (IRIF) as a biomarker for radiosensitivity

(2011) Aaron A. Goodarzi et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Study of interaction between Smad7 and DNA by single-molecule force spectroscopy

(2008) Xiaoli Shi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Targeted and Nontargeted Effects of Ionizing Radiation That Impact Genomic Instability

(2008) C. A. Maxwell et al.   CANCER RESEARCH

Regulation of TGF-β family signaling by E3 ubiquitin ligases

(2008) Yasumichi Inoue et al.   CANCER SCIENCE

TGFβ in Cancer

(2008) Joan Massagué   CELL

In vitro and In vivo Radiosensitization Induced by the DNA Methylating Agent Temozolomide

(2008) W. J. Kil et al.   CLINICAL CANCER RESEARCH

TGFβ-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFβ switch

(2008) Irwin M Liu et al.   EMBO JOURNAL

Transforming Growth Factor  -Induced Smad1/5 Phosphorylation in Epithelial Cells Is Mediated by Novel Receptor Complexes and Is Essential for Anchorage-Independent Growth

(2008) A. C. Daly et al.   MOLECULAR AND CELLULAR BIOLOGY

TRAF6 Mediates Smad-Independent Activation of JNK and p38 by TGF-β

(2008) Motozo Yamashita et al.   MOLECULAR CELL

Biochemical Kinetics Model of DSB Repair and Induction of γ-H2AX Foci by Non-homologous End Joining

(2008) Francis A. Cucinotta et al.   RADIATION RESEARCH

Specific ATM-Mediated Phosphorylation Dependent on Radiation Quality

(2008) Mary K. Whalen et al.   RADIATION RESEARCH