The PPFIA1-PP2A protein complex promotes trafficking of Kif7 to the ciliary tip and Hedgehog signaling

The kinesin-4 protein Kif7 regulates mammalian Hedgehog signalling by organizing the cilium tip compartment

(2014) Mu He et al.   NATURE CELL BIOLOGY

Hedgehog signaling from the primary cilium to the nucleus: an emerging picture of ciliary localization, trafficking and transduction

(2013) Yoko Inès Nozawa et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Proteomic Analysis of Mammalian Primary Cilia

(2012) Hiroaki Ishikawa et al.   CURRENT BIOLOGY

Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis

(2012) Z. J. Li et al.   DEVELOPMENT

Distinct Phosphorylations on Kinesin Costal-2 Mediate Differential Hedgehog Signaling Strength

(2012) Nadia Ranieri et al.   DEVELOPMENTAL CELL

IFT25 Links the Signal-Dependent Movement of Hedgehog Components to Intraflagellar Transport

(2012) Brian T. Keady et al.   DEVELOPMENTAL CELL

NovelKIF7mutations extend the phenotypic spectrum of acrocallosal syndrome

(2012) Audrey Putoux et al.   JOURNAL OF MEDICAL GENETICS

Mass spectrometry approaches to study mammalian kinase and phosphatase associated proteins

(2012) Michelle J. Kean et al.   METHODS

Antagonistic and Cooperative Actions of Kif7 and Sufu Define Graded Intracellular Gli Activities in Hedgehog Signaling

(2012) Kelvin King Lo Law et al.   PLoS One

Gli Proteins in Development and Disease

(2011) Chi-chung Hui et al.   Annual Review of Cell and Developmental Biology

Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu

(2011) S.-H. C. Hsu et al.   DEVELOPMENT

Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics

(2011) Claudia Dafinger et al.   JOURNAL OF CLINICAL INVESTIGATION

iProphet: Multi-level Integrative Analysis of Shotgun Proteomic Data Improves Peptide and Protein Identification Rates and Error Estimates

(2011) David Shteynberg et al.   MOLECULAR & CELLULAR PROTEOMICS

KIF7 mutations cause fetal hydrolethalus and acrocallosal syndromes

(2011) Audrey Putoux et al.   NATURE GENETICS

Complex interactions between genes controlling trafficking in primary cilia

(2011) Polloneal Jymmiel R Ocbina et al.   NATURE GENETICS

Ciliopathies

(2011) Friedhelm Hildebrandt et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sequential Phosphorylation of Smoothened Transduces Graded Hedgehog Signaling

(2011) Y. Su et al.   Science Signaling

Liprin α1 interacts with PP2A B56γ

(2010) Jason D. Arroyo et al.   CELL CYCLE

Costal 2 interactions with Cubitus interruptus (Ci) underlying Hedgehog-regulated Ci processing

(2010) Qianhe Zhou et al.   DEVELOPMENTAL BIOLOGY

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

(2010) E. W. Humke et al.   GENES & DEVELOPMENT

A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu–Gli protein complexes

(2010) Hanna Tukachinsky et al.   JOURNAL OF CELL BIOLOGY

Kinetics of Hedgehog-Dependent Full-Length Gli3 Accumulation in Primary Cilia and Subsequent Degradation

(2010) X. Wen et al.   MOLECULAR AND CELLULAR BIOLOGY

ProHits: integrated software for mass spectrometry–based interaction proteomics

(2010) Guomin Liu et al.   NATURE BIOTECHNOLOGY

The primary cilium: a signalling centre during vertebrate development

(2010) Sarah C. Goetz et al.   NATURE REVIEWS GENETICS

Sub-cellular distribution of UNC-104(KIF1A) upon binding to adaptors as UNC-16(JIP3), DNC-1(DCTN1/Glued) and SYD-2(Liprin-α) in C. elegans neurons

(2010) C.-C. Hsu et al.   NEUROSCIENCE

Coordinated Translocation of Mammalian Gli Proteins and Suppressor of Fused to the Primary Cilium

(2010) Huiqing Zeng et al.   PLoS One

The Mammalian Cos2 Homolog Kif7 Plays an Essential Role in Modulating Hh Signal Transduction during Development

(2009) Setsu Endoh-Yamagami et al.   CURRENT BIOLOGY

Mouse Kif7/Costal2 is a cilia-associated protein that regulates Sonic hedgehog signaling

(2009) K. F. Liem et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gli2 trafficking links Hedgehog-dependent activation of Smoothened in the primary cilium to transcriptional activation in the nucleus

(2009) J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic scaffolding protein SYD-2 clusters and activates kinesin-3 UNC-104 in C. elegans

(2009) O. I. Wagner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Kinesin Protein Kif7 Is a Critical Regulator of Gli Transcription Factors in Mammalian Hedgehog Signaling

(2009) H. O.-L. Cheung et al.   Science Signaling

PP4 and PP2A regulate Hedgehog signaling by controlling Smo and Ci phosphorylation

(2008) H. Jia et al.   DEVELOPMENT

A PP2A Phosphatase High Density Interaction Network Identifies a Novel Striatin-interacting Phosphatase and Kinase Complex Linked to the Cerebral Cavernous Malformation 3 (CCM3) Protein

(2008) Marilyn Goudreault et al.   MOLECULAR & CELLULAR PROTEOMICS