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Quantitative Phosphoproteomic Analysis of Soybean Root Hairs Inoculated withBradyrhizobium japonicum

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Modeling and predicting clinical efficacy for drugs targeting the tumor milieu

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An ATP-Site On-Off Switch That Restricts Phosphatase Accessibility of Akt

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AKT Inhibition Relieves Feedback Suppression of Receptor Tyrosine Kinase Expression and Activity

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Potent, Selective, and Orally Bioavailable Inhibitors of Mammalian Target of Rapamycin (mTOR) Kinase Based on a Quaternary Substituted Dihydrofuropyrimidine

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Discovery of a Potent, Selective, and Orally Available Class I Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Kinase Inhibitor (GDC-0980) for the Treatment of Cancer

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Systematic Comparison of Label-Free, Metabolic Labeling, and Isobaric Chemical Labeling for Quantitative Proteomics on LTQ Orbitrap Velos

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Expression of a functional VEGFR-1 in tumor cells is a major determinant of anti-PlGF antibodies efficacy

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mTOR Kinase Inhibition Causes Feedback-Dependent Biphasic Regulation of AKT Signaling

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A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression

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Integrated Quantitative Analysis of the Phosphoproteome and Transcriptome in Tamoxifen-resistant Breast Cancer

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Binding to the Extracellular Matrix and Proteolytic Processing: Two Key Mechanisms Regulating Vascular Endothelial Growth Factor Action

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mTOR: from growth signal integration to cancer, diabetes and ageing

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Pathway-Based Identification of Biomarkers for Targeted Therapeutics: Personalized Oncology with PI3K Pathway Inhibitors

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Targeting the PI3K signaling pathway in cancer

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Effects of the Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 on the Tumor Vasculature: Implications for Clinical Imaging

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The Identification of 2-(1H-Indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a Potent, Selective, Orally Bioavailable Inhibitor of Class I PI3 Kinase for the Treatment of Cancer†

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Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration

(2008) Mariona Graupera et al.   NATURE

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

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Class 1A PI3K regulates vessel integrity during development and tumorigenesis

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