Sodium channel-inhibiting drugs and survival of breast, colon and prostate cancer: a population-based study

How do voltage-gated sodium channels enhance migration and invasiveness in cancer cells?

(2015) Pierre Besson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The sodium channel-blocking antiepileptic drug phenytoin inhibits breast tumour growth and metastasis

(2015) Michaela Nelson et al.   Molecular Cancer

Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients

(2014) M. Tassara et al.   BLOOD

Long-term use of valproic acid in US veterans is associated with a reduced risk of smoking-related cases of head and neck cancer

(2014) Hyunseok Kang et al.   CANCER

Phase I study of anti-VEGF monoclonal antibody bevacizumab and histone deacetylase inhibitor valproic acid in patients with advanced cancers

(2014) Jennifer J. Wheler et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis

(2014) Michaela Nelson et al.   INTERNATIONAL JOURNAL OF CANCER

Ranolazine inhibits NaV1.5-mediated breast cancer cell invasiveness and lung colonization

(2014) Virginie Driffort et al.   Molecular Cancer

Exposure to sodium channel-inhibiting drugs and cancer survival: protocol for a cohort study using the QResearch primary care database: Table 1

(2014) Caroline Fairhurst et al.   BMJ Open

Can analyses of electronic patient records be independently and externally validated? The effect of statins on the mortality of patients with ischaemic heart disease: a cohort study with nested case–control analysis

(2014) David Reeves et al.   BMJ Open

The Long-Term Safety of Antiepileptic Drugs

(2013) Athanasios Gaitatzis et al.   CNS DRUGS

Long-term mortality risk by cause of death in newly diagnosed patients with epilepsy in Finland: a nationwide register-based study

(2013) Olli Nevalainen et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Noncanonical Roles of Voltage-Gated Sodium Channels

(2013) Joel A. Black et al.   NEURON

Abnormal neuronal patterning occurs during early postnatal brain development of Scn1b-null mice and precedes hyperexcitability

(2013) W. J. Brackenbury et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Exposure to bisphosphonates and risk of gastrointestinal cancers: series of nested case-control studies with QResearch and CPRD data

(2013) Y. Vinogradova et al.   BMJ-British Medical Journal

Therapeutic potential for phenytoin: targeting Nav1.5 sodium channels to reduce migration and invasion in metastatic breast cancer

(2012) Ming Yang et al.   BREAST CANCER RESEARCH AND TREATMENT

Voltage-gated sodium channel activity promotes prostate cancer metastasis in vivo

(2012) Senay Yildirim et al.   CANCER LETTERS

Voltage-gated sodium channels and metastatic disease

(2012) William J. Brackenbury   Channels

A voltage-gated sodium channel is essential for the positive selection of CD4+ T cells

(2012) Wan-Lin Lo et al.   NATURE IMMUNOLOGY

Statin Use and Reduced Cancer-Related Mortality

(2012) Sune F. Nielsen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cancer risk in people with epilepsy using valproate-sodium

(2011) G. Singh et al.   ACTA NEUROLOGICA SCANDINAVICA

The long-term risk of premature mortality in people with epilepsy

(2011) A. Neligan et al.   BRAIN

Na+ Channel ? Subunits: Overachievers of the Ion Channel Family

(2011) William J. Brackenbury et al.   Frontiers in Pharmacology

Voltage-Gated Na+ Channel SCN5A Is a Key Regulator of a Gene Transcriptional Network That Controls Colon Cancer Invasion

(2010) C. D. House et al.   CANCER RESEARCH

Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders

(2010) Massimo Mantegazza et al.   LANCET NEUROLOGY

Functional reciprocity between Na+ channel Nav1.6 and  1 subunits in the coordinated regulation of excitability and neurite outgrowth

(2010) W. J. Brackenbury et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Clinical and Biological Effects of Valproic Acid as a Histone Deacetylase Inhibitor on Tumor and Surrogate Tissues: Phase I/II Trial of Valproic acid and Epirubicin/FEC

(2009) P. Munster et al.   CLINICAL CANCER RESEARCH

Cancer mortality amongst people with epilepsy: A study of two cohorts with severe and presumed milder epilepsy

(2008) Gagandeep Singh et al.   EPILEPSY RESEARCH

Voltage-gated Na+channels: Potential for β subunits as therapeutic targets

(2008) William J Brackenbury et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

A novel adhesion molecule in human breast cancer cells: Voltage-gated Na+ channel β1 subunit

(2008) Athina-Myrto Chioni et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Voltage-Gated Na+ Channel  1 Subunit-Mediated Neurite Outgrowth Requires Fyn Kinase and Contributes to Postnatal CNS Development In Vivo

(2008) W. J. Brackenbury et al.   JOURNAL OF NEUROSCIENCE

An Emerging Role for Voltage-Gated Na+ Channels in Cellular Migration: Regulation of Central Nervous System Development and Potentiation of Invasive Cancers

(2008) William J. Brackenbury et al.   NEUROSCIENTIST

Epidermal growth factor upregulates motility of Mat-LyLu rat prostate cancer cells partially via voltage-gated Na+channel activity

(2007) Yanning Ding et al.   JOURNAL OF CELLULAR PHYSIOLOGY