Article
Microbiology
Pubo Chen, Jie Huang, Liuyu Rao, Wengen Zhu, Yuhe Yu, Fanshu Xiao, Xiaojuan Chen, Huang Yu, Yongjie Wu, Kui Xu, Xiafei Zheng, Ruiwen Hu, Zhili He, Qingyun Yan
Summary: Using the zebrafish model, this study aimed to clarify the potential mechanisms governing the resistance and resilience of gut microbiota after exposure to silver nanoparticles (AgNPs). The exposure to AgNPs significantly reduced the a-diversity of gut microbiota and led to noticeable changes in community composition. Resilience and resistance of gut microbiota responses to AgNPs may be determined by key taxa such as Acinetobacter and Gemmata, offering new insights into maintaining stability during environmental perturbations.
Article
Chemistry, Multidisciplinary
Xin-Lei Wang, Nanyang Yu, Chuan Wang, Hao-Ran Zhou, Chao Wu, Liuyan Yang, Si Wei, Ai-Jun Miao
Summary: In this study, mice were orally administered with silver nanoparticles (AgNPs) for 120 days. The results showed that AgNPs accumulated in the liver and caused changes in the gut microbiota (GM) structure and liver metabolism. The changes in GM structure were found to be correlated with alterations in liver metabolism.
Article
Biochemical Research Methods
Qingfeng Zhang, Kai Yu, Shihua Li, Xiaolong Zhang, Qi Zhao, Xia Zhao, Zekun Liu, Han Cheng, Ze-Xian Liu, Xiaoxing Li
Summary: The study introduced gutMEGA, a comprehensive database curating and hosting quantitative gut microbiota datasets from Homo sapiens. It integrated 59,132 quantification events for 6457 taxa under 776 conditions, providing users with a fast and simple way to access relative abundances of intestinal microbes through various browsing and search functions. GutMEGA is a convenient and comprehensive resource for gut metagenome research, available for free access at http://gutmega.omicsbio.info.
BRIEFINGS IN BIOINFORMATICS
(2021)
Article
Multidisciplinary Sciences
Lingling Wang, Haobin Yao, Daniel C. Morgan, Kam Shing Lau, Suet Yi Leung, Joshua W. K. Ho, Wai K. Leung
Summary: The study finds that antibiotic treatment for Helicobacter pylori leads to transient alteration in gut microbiota and significantly alters the previously less known gut virome community. Recurrent treatment further leads to lower virus community diversity and altered virus-bacteria interactions, compared with treatment naive patients.
NATURE COMMUNICATIONS
(2023)
Article
Food Science & Technology
Anna M. Malinowska, Marcin Schmidt, Dieuwertje E. Kok, Agata Chmurzynska
Summary: This study aimed to evaluate the relationship between lifestyle factors and the production of folates by gut microbiota, as well as the association between this potential and folate and tHcy levels in humans. The results showed that gut microbiota has the ability to synthesize folates, but this capacity does not predict human folate status.
FOOD RESEARCH INTERNATIONAL
(2022)
Review
Pharmacology & Pharmacy
Stephen C. Emencheta, Chinasa V. Olovo, Osita C. Eze, Chisom F. Kalu, Dinebari P. Berebon, Ebele B. Onuigbo, Marta M. D. C. Vila, Victor M. Balcao, Anthony A. Attama
Summary: Bacteriophages are nano-sized viruses that can live off bacteria and interact with bacterial cells in the gut microbiota, which has implications for human health.
Review
Biochemistry & Molecular Biology
Sergio Perez-Burillo, Beatriz Navajas-Porras, Alicia Lopez-Maldonado, Daniel Hinojosa-Nogueira, Silvia Pastoriza, Jose angel Rufian-Henares
Summary: Green tea can influence gut microbiota by either stimulating the growth of specific species or hindering the development of detrimental ones, benefiting health through beneficial bacteria or microbial bioactive metabolites. The inter-relation between green tea and gut microbiota is crucial for many health promoting effects of green tea, with the ability to correct microbial dysbiosis in conditions like obesity or cancer. Tea compounds influence the growth of bacterial species involved in inflammatory processes, potentially impacting the development of chronic diseases.
Review
Biochemistry & Molecular Biology
Kevin D. Seely, Cody A. Kotelko, Hannah Douglas, Brandon Bealer, Amanda E. Brooks
Summary: The gut microbiota has been shown to play a role in bone metabolism and the pathogenesis of osteoporosis. Despite the established connection between a healthy microbiome and bone homeostasis, the specific mechanisms underlying this relationship are not fully understood. Studying the interactions between the microbiome, osteoblasts, osteoclasts, and RANKL may offer insights into potential therapeutic targets for promoting bone health.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Microbiology
Muhammad Afzaal, Farhan Saeed, Yasir Abbas Shah, Muzzamal Hussain, Roshina Rabail, Claudia Terezia Socol, Abdo Hassoun, Mirian Pateiro, Jose M. Lorenzo, Alexandru Vasile Rusu, Rana Muhammad Aadil
Summary: The human gut contains a complex microbial community, which forms a connecting axis with other organs and plays a vital role in host-microbe interactions. Dysbiosis of the gut microbiota is linked to various human diseases. Understanding the role of gut microbiota in health and disease is crucial for maintaining health and treating diseases.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Microbiology
Leon M. T. Dicks, Diron Hurn, Demi Hermanus
Summary: The gut microbiota plays a key role in immune activation, intestinal permeability, enteric reflex, and entero-endocrine signaling, and is closely connected to the brain. Although the understanding of the role of gut microbiota in mood, cognitive behavior, and neuropsychiatric disorders is still limited, research in this area is crucial for developing novel therapeutic approaches.
Article
Biochemistry & Molecular Biology
Matthew R. Volpe, Jose A. Velilla, Martin Daniel-Ivad, Jenny J. Yao, Alessia Stornetta, Peter W. Villalta, Hsin-Che Huang, Daniel A. Bachovchin, Silvia Balbo, Rachelle Gaudet, Emily P. Balskus
Summary: In this study, small molecule boronic acid inhibitors were developed to inhibit the biosynthesis of the human gut bacterial genotoxin colibactin. These inhibitors effectively block the genotoxic effects of colibactin on eukaryotic cells by engaging with the peptidase ClbP. The availability of these inhibitors allows for precise control over colibactin production, enabling further study of its contributions to colorectal cancer.
NATURE CHEMICAL BIOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Aleksandra Sedzikowska, Leszek Szablewski
Summary: The majority of our body's epithelial surfaces and various systems are colonized by diverse microorganisms, which play crucial roles in digestion, metabolism, and vitamin synthesis. The composition of these microbiota is influenced by internal and external factors, with dysbiosis potentially leading to various diseases. The close relationship between the gut microbiota and human health highlights the potential role of these microorganisms in disease prevention and treatment.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Review
Biochemistry & Molecular Biology
Sanna Lensu, Satu Pekkala
Summary: A physically active lifestyle and exercise are associated with a healthy gut microbiota, benefiting from medium-intensity endurance exercise. However, this connection varies depending on study population and exercise protocol, and improvements induced by exercise may disappear in previously sedentary subjects. Controlling for diet in future longitudinal studies on the gut microbiota and physical performance is essential.
Article
Chemistry, Multidisciplinary
Wenqian Huang, Yirong Zhang, Zhi Li, Minjie Li, Fangfang Li, Monika Mortimer, Liang-Hong Guo
Summary: Medical applications of nanotechnology show promise, but the effects of nanodrugs on human microbiota have not been fully considered. This study found that medically relevant nanoparticles can affect the metabolism of beneficial bacteria and potentially alter the microbiota and immune signaling.
Review
Nutrition & Dietetics
Juntao Kan, Feng Wu, Feijie Wang, Jianheng Zheng, Junrui Cheng, Yuan Li, Yuexin Yang, Jun Du
Summary: Phytonutrients are natural bioactive components that can positively impact human health by improving their bioavailability. The gut microbiota plays a role in the metabolism of phytonutrients, enhancing their absorption and bioavailability. Additionally, phytonutrients can modulate the composition of the gut microbiota, improving the host's health.
FRONTIERS IN NUTRITION
(2022)
Article
Chemistry, Multidisciplinary
Xiaofei Gong, Jianbing Zhu, Jiazhan Li, Rui Gao, Qingyan Zhou, Zhen Zhang, Haozhen Dou, Lei Zhao, Xulei Sui, Jiajun Cai, Yunlong Zhang, Bing Liu, Yongfeng Hu, Aiping Yu, Shu-hui Sun, Zhenbo Wang, Zhongwei Chen
Summary: Iron-nitrogen-carbon materials are being studied as promising substitutes for Pt-based electrocatalysts for the oxygen reduction reaction. The 1D porous iron/nitrogen-doped carbon nanorods show exceptional ORR activities and demonstrate outstanding performance in Zn-air batteries.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Chemistry, Physical
Guangxin Song, Rui Gao, Zhao Zhao, Yujun Zhang, Huaqiao Tan, Haibo Li, Dandan Wang, Zaicheng Sun, Ming Feng
Summary: By incorporating Fe as a dopant in TiO2 nanoparticles, oxygen vacancies and dopant energy levels can be generated, promoting the adsorption and activation of N2 molecules. Surface modification with F induces Fe (III) in a high spin state and upshifts the dopant energy level, facilitating Fe 3d electrons backdonation to N 1ag* orbital to promote N2 molecule activation and reduce the limiting potential of NRR. The F-Fe: TiO2 electrocatalyst achieved the highest Faradaic efficiency and maximum NH3 production rate, providing insights into designing catalyst surface electronic states for efficient N2 to NH3 conversion.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2022)
Article
Environmental Sciences
Naiyi Yin, Xiaolin Cai, Pengfei Wang, Run Feng, Huili Du, Yaqi Fu, Guoxin Sun, Yanshan Cui
Summary: This study found that gut microbiota can influence the bioavailability of arsenic in soil and is related to the intake and excretion of arsenic in the human body.
SCIENCE OF THE TOTAL ENVIRONMENT
(2022)
Article
Chemistry, Physical
Maiwen Zhang, Ruilin Liang, Na Yang, Rui Gao, Yun Zheng, Ya-Ping Deng, Yongfeng Hu, Aiping Yu, Zhongwei Chen
Summary: The study successfully synthesized MXene materials with tunable in-plane porosity using a eutectic mixture etching strategy, optimizing pore structure and surface termination to improve material mesoporosity and surface area. The mesoporous Ti3C2Cl2 exhibited high charge capacity and cycling stability in dual-ion battery applications after optimizations.
ADVANCED ENERGY MATERIALS
(2022)
Review
Chemistry, Physical
Lei Zhao, Jianbing Zhu, Yun Zheng, Meiling Xiao, Rui Gao, Zhen Zhang, Guobin Wen, Haozhen Dou, Ya-Ping Deng, Aiping Yu, Zhenbo Wang, Zhongwei Chen
Summary: Proton exchange membrane fuel cells (PEMFCs) have been widely used in commercial markets, especially in the automotive industry. However, the durability of current electrocatalysts, which are crucial for the performance of PEMFCs, remains a significant challenge. Finding strategies to improve the lifespan of electrocatalysts is crucial for practical application in PEMFCs.
ADVANCED ENERGY MATERIALS
(2022)
Article
Engineering, Environmental
Chuanfang Fan, Naiyi Yin, Xiaolin Cai, Xin Du, Pengfei Wang, Xiaotong Liu, Yunpeng Li, Xuhui Chang, Huili Du, Jingnan Ma, Yanshan Cui
Summary: Modified-biochar materials were synthesized and used for the remediation of F-contaminated soil. The results showed that BC/Al-La was the most effective in stabilizing F, significantly reducing the concentration of water soluble fluoride. Additionally, a molar ratio of 1:1:1 for BC: Al3+ or Fe3+: La3+ showed better results.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
Pengfei Wang, Huili Du, Yaqi Fu, Xiaolin Cai, Naiyi Yin, Yanshan Cui
Summary: This study reveals the important roles of gut bacteria in arsenic biosorption and biotransformation, with Escherichia coli showing the strongest tolerance and reducing ability.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Engineering, Environmental
Xiaolin Cai, Zhennan Zhang, Naiyi Yin, Wenyi Lu, Huili Du, Mei Yang, Liwei Cui, Shibao Chen, Yanshan Cui
Summary: This study investigates the controlling mechanisms of microbial As(III) oxidation in As(III)-adsorbed Fe minerals through incubation with As(III)-oxidizing bacteria at different pH conditions. The results show that the percentage of As(III) oxidized to As(V) significantly increases under neutral and alkaline conditions. The As(III) adsorption complexes formed on hematite are more stable than those on magnetite, limiting the activity and mobility of strain HN-1.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Environmental Sciences
Naiyi Yin, Zeliang Han, Wenbin Jia, Yaqi Fu, Jingnan Ma, Xiaotong Liu, Xiaolin Cai, Yan Li, Xiaochen Chen, Yanshan Cui
Summary: The study revealed that the supplementation of vitamin C increased the oral bioaccessibility of lead in contaminated soils, mainly by enhancing the release of lead in the gastric phase and its reduction in the intestinal phase. However, there is a higher non-carcinogenic risk associated with this, highlighting the need for careful management of vitamin C supplements for individuals exposed to lead in soil.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Soil Science
Xiaolin Cai, Naiyi Yin, Xiaotong Liu, Pengfei Wang, Huili Du, Yanshan Cui, Zhengyi Hu
Summary: The mobilization of soil arsenic is influenced by soil properties such as iron, sulfur, and organic matter content. This study investigated the mechanisms of arsenic reduction and redistribution in different soils using sequential soil extraction and X-ray absorption spectroscopy. The results showed that the dominant biogeochemical pathways controlling arsenic fate varied depending on the soil's iron, sulfur, and organic matter content.
Article
Environmental Sciences
Hong -Bo Li, Rong-Yue Xue, Xiao-Qiang Chen, Xin-Ying Lin, Xiao-Xia Shi, Hai-Yan Du, Nai-Yi Yin, Yan-Shan Cui, Li-Na Li, Kirk G. Scheckel, Albert L. Juhasz, Xi-Mei Xue, Yong-Guan Zhu, Lena Q. Ma
Summary: This study evaluated the ability of different calcium minerals to reduce the oral bioavailability of lead, cadmium, and arsenic from indoor dust. The results showed that different calcium minerals had varying effects on the bioavailability of these metals. Organic calcium minerals had higher bioavailability for lead and cadmium, while calcium phosphate had lower bioavailability for lead and aspartate had lower bioavailability for arsenic.
ENVIRONMENTAL HEALTH PERSPECTIVES
(2022)
Article
Environmental Sciences
Naiyi Yin, Xuhui Chang, Peng Xiao, Yi Zhou, Xiaotong Liu, Shimao Xiong, Pengfei Wang, Xiaolin Cai, Guoxin Sun, Yanshan Cui, Zhengyi Hu
Summary: The gut microbiota plays a protective role against arsenic-induced toxicity, and the metabolism of arsenic is an important part of risk assessment related to soil exposure. However, the role of microbial iron(III) reduction in the metabolism of soil-bound arsenic in the human gut is not well understood.
ENVIRONMENT INTERNATIONAL
(2023)
Article
Engineering, Environmental
Xiaotong Liu, Xiaolin Cai, Pengfei Wang, Naiyi Yin, Chuanfang Fan, Xuhui Chang, Xuhan Huang, Xin Du, Shuping Wang, Yanshan Cui
Summary: This study investigates the impact of manganese oxide on the fate of different Fe-minerals-adsorbed As in the presence of As(V)-reducing bacteria. The results show that manganese oxide can effectively reduce the release of arsenic and has the most significant oxidation and immobilization effect on goethite-adsorbed As.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Engineering, Environmental
Yunpeng Li, Naiyi Yin, Xiaolin Cai, Pengfei Wang, Chuanfang Fan, Xuhui Chang, Xiaotong Liu, Ziqi Geng, Liwei Cui, Xin Du, Yanshan Cui
Summary: Dietary calcium intake can reduce fluoride bioavailability in contaminated soils, according to in vitro and in vivo experiments. Various calcium salts commonly found in calcium supplements were found to significantly decrease fluoride bioaccessibility in the stomach and small intestine. The results suggest that calcium supplementation can be effective in reducing health risks associated with soil fluoride exposure.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Toshimi Nakajima, Mao Kuragano, Makoto Yamada, Ryo Sugimoto
Summary: This study compared the contribution of submarine groundwater discharge (SGD) to river nutrient budgets at nearshore and embayment scales, and found that SGD-derived nutrients become more important at larger spatial scales.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Fan Liu, Lei Zhang, Chongyang Zhang, Ziguang Chen, Jingguang Li
Summary: NO2 emissions from wall-mounted gas stoves used for household heating have become a significant source of indoor pollution in Chinese urban areas. The high indoor concentration of NO2 poses potential health risks to residents. It is urgently necessary to establish relevant regulations and implement emission reduction technologies to reduce NO2 emissions from wall-mounted gas stoves.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Letter
Environmental Sciences
Hans Peter H. Arp, Raoul Wolf, Sarah E. Hale, Sivani Baskaran, Juliane Gluege, Martin Scheringer, Xenia Trier, Ian T. Cousins, Harrie Timmer, Roberta Hofman-Caris, Anna Lennquist, Andre D. Bannink, Gerard J. Stroomberg, Rosa M. A. Sjerps, Rosa Montes, Rosario Rodil, Jose Benito Quintana, Daniel Zahn, Herve Gallard, Tobias Mohr, Ivo Schliebner, Michael Neumann
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Philomina Onyedikachi Peter, Binessi Edouard Ifon, Francois Nkinahamira, Kayode Hassan Lasisi, Jiangwei Li, Anyi Hu, Chang-Ping Yu
Summary: This study investigates the relationship between dissolved organic matter (DOM) and Rare Earth Elements (REEs) in sediments from Yundang Lagoon, China. The results show four distinct fluorescent components, with protein-like substances being the most prevalent. Additionally, the total fluorescence intensity and LREE concentrations exhibit a synchronized increase from Outer to Inner to Songbai Lake core sediments. The findings demonstrate a strong correlation between DOM content and pollution levels.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Surya Gupta, Pasquale Borrelli, Panos Panagos, Christine Alewell
Summary: The objective of this study is to incorporate soil hydraulic properties into the erodibility factor (K) of USLE-type models. By modifying and improving the existing equations for soil texture and permeability, the study successfully included information on saturated hydraulic conductivity (Ksat) into the calculation of K factor. Using the Random Forest machine learning algorithm, two independent K factor maps with different spatial resolutions were generated. The results show that the decrease in K factor values has a positive impact on the modeling of soil erosion rates.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jesmin Akter, Wendy J. M. Smith, Yawen Liu, Ilho Kim, Stuart L. Simpson, Phong Thai, Asja Korajkic, Warish Ahmed
Summary: The choice of workflow in wastewater surveillance has a significant impact on SARS-CoV-2 concentrations, while having minimal effects on HF183 and no effect on HAdV 40/41 concentrations. Certain components in the workflow can be interchangeable, but factors such as buffer type, chloroform, and homogenization speed can affect the recovery of viruses and bacteria.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yu Luo, Xueting Yang, Diwei Wang, Hongmei Xu, Hongai Zhang, Shasha Huang, Qiyuan Wang, Ningning Zhang, Junji Cao, Zhenxing Shen
Summary: Atmospheric PM2.5, which can generate reactive oxygen species (ROS), is associated with cardiorespiratory morbidity and mortality. The study found that both the mass concentration of PM2.5 and the DTT activity were higher during the heating season than during the nonheating season. Combustion sources were the primary contributors to DTT activity during the heating season, while secondary formation dominated during the nonheating season. The study also revealed that biomass burning had the highest inherent oxidation potential among all sources investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Erin L. Murphy, Leah R. Gerber, Chelsea M. Rochman, Beth Polidoro
Summary: Plastic pollution has devastating consequences for marine organisms. This study uses a trait-based framework to develop a vulnerability index for marine mammals, seabirds, and sea turtles in Hawai'i. The index ranks 63 study species based on their vulnerability to macroplastic pollution, providing valuable information for species monitoring and management priorities.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Kenji Maurice, Amelia Bourceret, Sami Youssef, Stephane Boivin, Liam Laurent-Webb, Coraline Damasio, Hassan Boukcim, Marc-Andre Selosse, Marc Ducousso
Summary: Growing pressure from climate change and agricultural land use is destabilizing soil microbial community interactions. Little is known about microbial community resistance and adaptation to disturbances, hindering our understanding of recovery latency and implications for ecosystem functioning. This study found that anthropic disturbance and natural disturbance have different effects on the topology and stability of soil microbial networks.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Yunhao Li, Yali Feng, Haoran Li, Yisong Yao, Chenglong Xu, Jinrong Ju, Ruiyu Ma, Haoyu Wang, Shiwei Jiang
Summary: Deep-sea mining poses a serious threat to marine ecosystems and human health by disturbing sediment and transmitting metal ions through the food chain. This study developed a new regenerative adsorption material, OMN@SA, which effectively removes metal ions. The adsorption mechanism and performance of the material for metal ion fixation were investigated.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Antonio Medici, Margherita Lavorgna, Marina Isidori, Chiara Russo, Elena Orlo, Giovanni Luongo, Giovanni Di Fabio, Armando Zarrelli
Summary: Valsartan, a widely used antihypertensive drug, has been detected in high concentrations in surface waters due to its unchanged excretion and incomplete degradation in wastewater treatment plants. This study investigated the degradation of valsartan and identified 14 degradation byproducts. The acute and chronic toxicity of these byproducts were evaluated in key organisms in the freshwater trophic chain.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Jiang Lin, Lianbao Chi, Qing Yuan, Busu Li, Mingbao Feng
Summary: This study investigated the photodegradation behavior and product formation of two representative pharmaceuticals in simulated estuary water. The study found that the formed transformation products of these pharmaceuticals have potential toxicity on marine organisms, including oxidative stress and damage to cellular components.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Hua Fang, Dongdong Jiang, Ye He, Siyi Wu, Yuehong Li, Ziqi Zhang, Haoting Chen, Zixin Zheng, Yan Sun, Wenxiang Wang
Summary: This study revealed that exposure to lower levels of air pollutants led to decreased pregnancy rates, with PM10, NO2, SO2, and CO emerging as the four most prominent pollutants. Individuals aged 35 and above exhibited heightened susceptibility to pollutants.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Ali Shaan Manzoor Ghumman, Rashid Shamsuddin, Amin Abbasi, Mohaira Ahmad, Yoshiaki Yoshida, Abdul Sami, Hamad Almohamadi
Summary: In this study, inverse vulcanized polysulfides (IVP) were synthesized by reacting molten sulfur with 4-vinyl benzyl chloride, and then functionalized using N-methyl D-glucamine (NMDG). The functionalized IVP showed a high mercury adsorption capacity and a machine learning model was developed to predict the amount of mercury removed. Furthermore, the functionalized IVP can be regenerated and reused, providing a sustainable and cost-effective adsorbent.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)
Article
Environmental Sciences
Rita Bonfiglio, Renata Sisto, Stefano Casciardi, Valeria Palumbo, Maria Paola Scioli, Erica Giacobbi, Francesca Servadei, Gerry Melino, Alessandro Mauriello, Manuel Scimeca
Summary: This study investigated the presence of aluminum in human colon cancer samples and its potential association with biological processes involved in cancer progression. Aluminum was found in tumor areas of 24% of patients and was associated with epithelial to mesenchymal transition (EMT) and cell death. Additional analyses revealed higher tumor mutational burden and mutations in genes related to EMT and apoptosis in aluminum-positive colon cancers. Understanding the molecular mechanisms of aluminum toxicity may improve strategies for the management of colon cancer patients.
SCIENCE OF THE TOTAL ENVIRONMENT
(2024)