Journal
RSC ADVANCES
Volume 5, Issue 99, Pages 81445-81448Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra15516a
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Funding
- Natural Science Foundation of China [21204025, 81473142, 81373344]
- Ministry of Science and Technology of China (International Cooperation and Communication Program) [2011DFR51090]
- Science & Technology Department of Jilin Province [20130522005JH, 20140101140JC]
- Fundamental Research Funds for the Central Universities [JCKY-QKJC30]
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Porous PLGA microparticles were successfully prepared for achieving the co-delivery of doxorubicin and PEI25K/miR-34a, using ammonium bicarbonate as a porogen. The synergistic effect between these two components ensured the efficient anti-proliferative and anti-migration effects of porous PLGA microparticles on tumor cells.
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