Targeting Kynurenine Aminotransferase II in Psychiatric Diseases: Promising Effects of an Orally Active Enzyme Inhibitor

Evaluating the role of the alpha-7 nicotinic acetylcholine receptor in the pathophysiology and treatment of schizophrenia

(2013) Jared W. Young et al.   BIOCHEMICAL PHARMACOLOGY

PF-04859989 as a template for structure-based drug design: Identification of new pyrazole series of irreversible KAT II inhibitors with improved lipophilic efficiency

(2013) Amy B. Dounay et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Nicotinic  7 receptors enhance NMDA cognitive circuits in dorsolateral prefrontal cortex

(2013) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Glutamatergic Synapse Formation is Promoted by  7-Containing Nicotinic Acetylcholine Receptors

(2012) A. F. Lozada et al.   JOURNAL OF NEUROSCIENCE

Kynurenines in the mammalian brain: when physiology meets pathology

(2012) Robert Schwarcz et al.   NATURE REVIEWS NEUROSCIENCE

NMDA Receptor and Schizophrenia: A Brief History

(2012) J. T. Coyle   SCHIZOPHRENIA BULLETIN

Fluctuations in Endogenous Kynurenic Acid Control Hippocampal Glutamate and Memory

(2011) Ana Pocivavsek et al.   NEUROPSYCHOPHARMACOLOGY

Cognition in schizophrenia: core psychological and neural mechanisms

(2011) Deanna M. Barch et al.   TRENDS IN COGNITIVE SCIENCES

A Possible Role for the Striatum in the Pathogenesis of the Cognitive Symptoms of Schizophrenia

(2010) Eleanor H. Simpson et al.   NEURON

Impaired Kynurenine Pathway Metabolism in The Prefrontal Cortex of Individuals With Schizophrenia

(2010) K. V. Sathyasaikumar et al.   SCHIZOPHRENIA BULLETIN

L-kynurenine treatment alters contextual fear conditioning and context discrimination but not cue-specific fear conditioning

(2009) Amy C. Chess et al.   BEHAVIOURAL BRAIN RESEARCH

Structure, expression, and function of kynurenine aminotransferases in human and rodent brains

(2009) Qian Han et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Pharmacological Manipulation of Kynurenic Acid

(2009) Sophie Erhardt et al.   CNS DRUGS

Astrocyte-derived kynurenic acid modulates basal and evoked cortical acetylcholine release

(2009) A. Zmarowski et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

The Astrocyte-Derived α7 Nicotinic Receptor Antagonist Kynurenic Acid Controls Extracellular Glutamate Levels in the Prefrontal Cortex

(2009) Hui-Qiu Wu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

On the relationship between the two branches of the kynurenine pathway in the rat brainin vivo

(2009) Laura Amori et al.   JOURNAL OF NEUROCHEMISTRY

Specific inhibition of kynurenate synthesis enhances extracellular dopamine levels in the rodent striatum

(2008) L. Amori et al.   NEUROSCIENCE