Article
Psychiatry
Isabel Ruiz-Delgado, Berta Moreno-Kuestner, Monica Garcia-Medina, Maria Luisa Barrigon, Fermin Gonzalez-Higueras, Raguel Lopez-Carrilero, Irene Barrios-Mellado, Ana Barajas, Esther Pousa, Esther Lorente-Rovira, Eva Grasa, Jordi Cid, Paula Barrau-Sastre, Steffen Moritz, Susana Ochoa, Spanish Metacognition Group
Summary: This multicenter randomized clinical trial found that Metacognitive Training (MCT) is an effective psychological intervention for improving memory, attention, and executive function in first-episode psychosis patients.
PSYCHIATRY RESEARCH
(2022)
Article
Psychology, Clinical
Dan Foti, Greg Perlman, Evelyn J. Bromet, Philip D. Harvey, Greg Hajcak, Daniel H. Mathalon, Roman Kotov
Summary: This study examined the relationship between neural measures of performance monitoring and executive function, symptoms, and functioning in individuals with psychotic disorders. The results showed that reduced error-related negativity and error positivity were associated with impaired executive function, negative symptom severity, and poor real-world functioning in the clinical cohort. Multiple potential pathways were identified, suggesting a transdiagnostic model of psychotic disorders where poor performance monitoring contributes to impaired executive function, negative symptoms, and poor functioning.
PSYCHOLOGICAL MEDICINE
(2021)
Article
Clinical Neurology
Bernice J. A. Gulpers, Frans R. J. Verhey, Simone J. P. M. Eussen, Miranda T. Schram, Bastiaan E. de Galan, Martin P. J. van Boxtel, Coen D. A. Stehouwer, S. Kohler
Summary: This study investigates the relationship between individual anxiety disorders, generalized anxiety symptoms, and multiple cognitive domains. The results show that agoraphobia is associated with worse scores on all cognitive domains and higher odds of cognitive impairment. High scores on the Generalized Anxiety Disorder 7-item scale (GAD-7) are associated with worse scores on processing speed and higher odds of cognitive impairment. Panic disorder is significantly associated with worse scores on memory tasks. These associations are stronger in younger participants and in those with type 2 diabetes.
JOURNAL OF AFFECTIVE DISORDERS
(2022)
Article
Nutrition & Dietetics
Christopher Papandreou, Christos Papagiannopoulos, Myrto Koutsonida, Afroditi Kanellopoulou, Georgios Markozannes, Georgios Polychronidis, Andreas G. Tzakos, Georgios A. Fragkiadakis, Evangelos Evangelou, Evangelia Ntzani, Ioanna Tzoulaki, Eleni Aretouli, Konstantinos K. Tsilidis
Summary: This study aimed to generate a metabolite profile for adherence to the Mediterranean diet (MedDiet) and evaluate its association with cognitive performance. The study found that in a middle-aged Mediterranean population, the metabolite profile related to adherence to the MedDiet was not associated with cognitive test results.
CLINICAL NUTRITION
(2023)
Review
Clinical Neurology
Josephine Power, Marinus van IJzendoorn, Andrew J. Lewis, Wai Chen, Megan Galbally
Summary: The systematic review and meta-analysis revealed inadequate assessment of maternal depression and unreliable measures of executive function in many studies. However, there was a small yet statistically significant relationship between perinatal depression and child executive function, supporting the hypothesis that maternal depression during the perinatal period impacts offspring's executive function. Future studies should focus on robust measurement of depression and executive function, and consider the chronicity of maternal depression and developmental context for meaningful results.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Geriatrics & Gerontology
Chen Zhu, Natalie Thomas, Shalini Arunogiri, Caroline Gurvich
Summary: This review examines the relationships between cognition, menopausal symptoms, and risk/protective factors. The findings suggest that factors associated with cognition and menopausal symptoms can be categorized into demographic, socio-economic, lifestyle, and reproductive factors.
Article
Public, Environmental & Occupational Health
Ruijia Chen, David R. Williams, Kristen Nishimi, Natalie Slopen, Laura D. Kubzansky, Jennifer Weuve
Summary: This study found that cumulative stress exposure is associated with poorer cognitive function and faster cognitive decline. Both high stress in childhood and adulthood were linked to lower executive function and episodic memory. However, there was little evidence to suggest that the rate of decline in cognitive function differed across levels of stress exposure.
SOCIAL SCIENCE & MEDICINE
(2022)
Article
Biochemistry & Molecular Biology
Juan Angel Carrillo, Raul Arcusa, Maria Pilar Zafrilla, Javier Marhuenda
Summary: The study involving 108 healthy volunteers over a 16-week consumption period showed significant improvements in cognitive function by consuming a micronized fruit and vegetable-based preparation, particularly in areas such as short-term memory, verbal and non-verbal memory.
Article
Psychology, Educational
Nadia Chernyak, Paul L. Harris, Sara Cordes
Summary: Recent work has examined the developmental mechanisms that promote fair sharing and found that number knowledge is associated with fair sharing, even after controlling for other factors and age. Additionally, a counting intervention has been shown to improve children's sharing behavior.
Article
Geriatrics & Gerontology
Arne Stinchcombe, Nicole G. Hammond
Summary: This study examined the relationship between proxy measures of minority stress and cognitive health in a large sample of Canadians aged 45-85 years. The results showed that demographic and health variables were associated with cognitive performance, and racial minority status was consistently associated with lower cognitive performance. These findings help identify risk factors for cognitive decline and promote health equity.
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
(2022)
Review
Oncology
Renato Gondar, Gildas Patet, Karl Schaller, Torstein R. Meling
Summary: Assessment of cognition in brain tumor care is often overlooked in clinical outcomes, leading to potentially underestimated impact on patients' quality of life. Treatment for meningiomas can have early cognitive effects, but long-term conclusions are limited by short follow-up times. Standardized and reproducible cognitive testing should be a focus of future research to better understand the cognitive outcomes in meningioma patients, as cognitive dimensions and quality of life may be undervalued in clinical assessments.
Article
Geriatrics & Gerontology
Annalise A. LaPlume, Nicole D. Anderson, Larissa McKetton, Brian Levine, Angela K. Troyer
Summary: The study found that cognitive performance gradually declines in adulthood, with a shift to rapid decline around the age of 60. Variability between individuals and within tasks also increases gradually until around age 60, then rapidly increases. Some individuals show less cognitive decline than others, and some cognitive abilities have less within-person decline than others.
JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Wiktor Bilecki, Agnieszka Wawrzczak-Bargiela, Iwona Majcher-Maslanka, Magdalena Chmelova, Marzena Mackowiak
Summary: The study revealed that schizophrenia-like abnormalities induced by MAM were only observed in males, while adolescent JQ1 treatment affected memory recognition and altered the molecular and proteomic landscape in the mPFC of both sexes.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Nursing
Chia-Chi Chang, Hua-Shan Wu, Chen-Jee Hong, Chieh-Yu Liu, Chi-Wen Chen, Chiu-Yueh Yang
Summary: This study explored the effects of group cognitive stimulation training (GCST) on cognitive function and social function in people with schizophrenia. The results showed that GCST positively impacted overall cognitive and social functions, but not higher-order cognitive functions.
JOURNAL OF NURSING RESEARCH
(2023)
Article
Psychiatry
Nora S. Vyas, Lisa Burke, Siobhan Netherwood, Paul Caviston, Mima Simic, Monte S. Buchsbaum
Summary: This study investigated the neurocognitive profiles of patients with Early-Onset Schizophrenia (EOS) and their unaffected siblings. The findings revealed that EOS patients showed deficits in working memory, attention, and executive function compared to their siblings. The duration of illness was found to be more important in older patients. The similarity in cognitive task performance between siblings and the greater variability in patient scores across tasks provide support for the neurobiological heterogeneity in schizophrenia.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY
(2022)
Review
Psychology, Clinical
Anna B. Chaplin, Natasha F. Daniels, Diana Ples, Rebecca Z. Anderson, Amy Gregory-Jones, Peter B. Jones, Golam M. Khandaker
Summary: High BMI and smoking are associated with subsequent depression in young people, while low but not high SBP increases the risk of depression. The generalizability of the findings may be limited as most studies were based in North America or Europe.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Developmental
Emma Soneson, Stephen Puntis, Nikki Chapman, Karen L. Mansfield, Peter B. Jones, Mina Fazel
Summary: Relatively little research has been done on children and young people whose mental health and wellbeing improved during the Covid-19 lockdown. In this study, one-third of the participating CYP reported improved mental wellbeing during the first UK national lockdown. These CYP had better relationships with friends and family, experienced less loneliness and exclusion, faced reduced bullying, managed school tasks better, and engaged in more sleep and exercise compared to their peers who reported no change or deterioration in mental wellbeing. Understanding why these CYP fared better during lockdown and finding ways to sustain these positive experiences beyond the pandemic can contribute to promoting the future mental health and wellbeing of school-aged CYP.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Article
Psychology, Developmental
Jan Stochl, Hannah Jones, Emma Soneson, Adam P. Wagner, Golam M. Khandaker, Stanley Zammit, Jon Heron, Gemma Hammerton, Edward T. Bullmore, Ray Dolan, Peter Fonagy, Ian M. Goodyer, J. Perez, Peter B. Jones
Summary: Characterizing patterns of mental phenomena in epidemiological studies of adolescents can provide insight into the latent organization of psychiatric disorders. This avoids the biases of chronicity and selection inherent in clinical samples, guides models of shared aetiology within psychiatric disorders and informs the development and implementation of interventions.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Review
Nursing
Heli Kerimaa, Heidi Ruotsalainen, Helvi Kyngas, Jouko Miettunen, Tarja Polkki
Summary: This systematic review found that certain preparatory interventions can reduce parental anxiety and stress, and alleviate children's fear and pain. However, more randomized controlled trials are needed to determine the most effective methods for preparing parents and children for day surgery.
JOURNAL OF CLINICAL NURSING
(2023)
Article
Psychology, Clinical
Victoria Rodriguez, Luis Alameda, Diego Quattrone, Giada Tripoli, Charlotte Gayer-Anderson, Edoardo Spinazzola, Giulia Trotta, Hannah E. Jongsma, Simona Stilo, Caterina La Cascia, Laura Ferraro, Daniele La Barbera, Antonio Lasalvia, Sarah Tosato, Ilaria Tarricone, Elena Bonora, Stephane Jamain, Jean-Paul Selten, Eva Velthorst, Lieuwe de Haan, Pierre-Michel Llorca, Manuel Arrojo, Julio Bobes, Miguel Bernardo, Celso Arango, James Kirkbride, Peter B. Jones, Bart P. Rutten, Alexander Richards, Pak C. Sham, Michael O'Donovan, Jim Van Os, Craig Morgan, Marta Di Forti, Robin M. Murray, Evangelos Vassos
Summary: This study suggests that combining polygenic risk scores (PRS) for severe psychiatric disorders with prediction models for psychosis phenotypes can improve discrimination ability and enhance our understanding of these phenotypes. PRS may have potential usefulness in specific populations such as those at high risk or in the early stages of psychosis.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Andrew J. Watson, Annalisa Giordano, John Suckling, Thomas R. E. Barnes, Nusrat Husain, Peter B. Jones, Carl R. Krynicki, Stephen M. Lawrie, Shon Lewis, Naghmeh Nikkheslat, Carmine M. Pariante, Rachel Upthegrove, Bill Deakin, Paola Dazzan, Eileen M. Joyce
Summary: This study identified cognitive subtypes based on IQ in patients with early-phase schizophrenia-spectrum disorder. The compromised IQ subtype was associated with smaller brain volume and higher levels of low-grade inflammation markers. This adds validity to the existence of a neurodevelopmental subtype of schizophrenia.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychology, Clinical
Monica Aas, Luis Alameda, Marta Di Forti, Diego Quattrone, Paola Dazzan, Antonella Trotta, Laura Ferraro, Victoria Rodriguez, Evangelos Vassos, Pak Sham, Giada Tripoli, Caterina La Cascia, Daniele La Barbera, Ilaria Tarricone, Roberto Muratori, Domenico Berardi, Antonio Lasalvia, Sarah Tosato, Andrei Szoke, Pierre-Michel Llorca, Celso Arango, Andrea Tortelli, Lieuwe de Haan, Eva Velthorst, Julio Bobes, Miguel Bernardo, Julio Sanjuan, Jose Luis Santos, Manuel Arrojo, Cristina Marta Del-Ben, Paulo Rossi Menezes, Jean-Paul Selten, Peter B. Jones, Hannah E. Jongsma, James B. Kirkbride, Bart P. F. Rutten, Jim van Os, Charlotte Gayer-Anderson, Robin M. Murray, Craig Morgan
Summary: This study found possible synergistic effects of childhood adversity experiences and high polygenic risk scores for schizophrenia in the onset of first-episode psychosis. However, larger samples are needed for more precise estimation.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Psychiatry
Antti Mustonen, Anni-Emilia Alakokkare, James G. Scott, Anu-Helmi Halt, Miika Vuori, Tuula Hurtig, Alina Rodriguez, Jouko Miettunen, Solja Niemela
Summary: This study investigated the association between symptoms of attention deficit hyperactive disorder (ADHD) in adolescents and risk of mortality. The results showed that higher scores in inattentive, hyperactive, and combined symptoms were associated with increased risk of death. However, this association was partially attenuated by adolescent substance use.
NORDIC JOURNAL OF PSYCHIATRY
(2023)
Article
Psychology, Clinical
Maria Protsenko, Martta Kerkela, Jouko Miettunen, Juha Auvinen, Marjo-Riitta Jarvelin, Peter B. Jones, Mika Gissler, Juha Veijola
Summary: There is a familial association between parental severe mental illness (SMI) and obesity in middle-aged offspring, especially in the offspring of mothers with SMI.
PSYCHOLOGICAL MEDICINE
(2023)
Article
Dermatology
Jussi Tuusa, Nina Kokkonen, Anja Mattila, Laura Huilaja, Outi Varpuluoma, Sirpa Rannikko, Virpi Glumoff, Jouko Miettunen, Kaisa Tasanen
Summary: Dipeptidyl peptidase 4 inhibitors (DPP4is), commonly used drugs for type 2 diabetes, increase the risk of bullous pemphigoid (BP). The mechanism leading to the loss of immunological tolerance and the differences between DPP4i-associated BP (DPP4i-BP) and regular BP are largely unknown. This study analyzed cytokine expression in lesional and nonlesional skin samples of patients with regular BP or DPP4i-BP, and found distinct molecular fingerprints between the two.
JOURNAL OF INVESTIGATIVE DERMATOLOGY
(2023)
Article
Psychiatry
Tuomas Majuri, Anni-Emilia Alakokkare, Marianne Haapea, Tanja Nordstrom, Jouko Miettunen, Erika Jaaskelainen, Leena Ala-Mursula
Summary: This study compared employment trajectories among individuals with schizophrenia, other psychoses, and without psychosis. The findings showed that most individuals with mental illnesses had unstable employment trajectories, indicating a higher risk of unemployment and part-time work. The study highlights the importance of improving labor market attachment during the early stages of mental illness.
SOCIAL PSYCHIATRY AND PSYCHIATRIC EPIDEMIOLOGY
(2023)
Article
Business
Mikko Vaaramo, Leena Ala-Mursula, Jouko Miettunen, Marko Korhonen
Summary: This study examines the differences in economic preferences and temperament traits between different categories of business leaders (i.e., managers, self-employed with employees, self-employed without employees) and paid employees. The results show that business leaders generally have different economic preferences and temperament traits compared to paid employees. The temperament trait of novelty-seeking seems relevant for becoming a manager, while the economic preference of risk-taking appears important for becoming self-employed.
SMALL BUSINESS ECONOMICS
(2023)
Article
Psychiatry
Johanna Palomaki, Sebastian Therman, Martta Kerkela, Marjo-Riitta Jarvelin, Peter Jones, Graham K. Murray, Tanja Nordstrom, Markus Heinimaa, Jouko Miettunen, Juha Veijola, Tiina Riekki
Summary: This study examined the relationship between specific adolescent psychotic-like symptoms and psychiatric disorders. Three symptoms were found to be associated with the onset of psychosis, which is a significant finding.
EARLY INTERVENTION IN PSYCHIATRY
(2023)
Article
Public, Environmental & Occupational Health
Anna-Kaisa Karppanen, Jouko Miettunen, Tuula Hurtig, Tanja Nordstroem, Tuija Tammelin, Raija Korpelainen
Summary: This population-based birth cohort study examines the associations between self-reported temperament at age 31 and self-reported leisure-time physical activity (MVPA) levels and changes from age 31 to age 46. The results suggest that temperament may play a role in determining the level and sustainability of MVPA.
