4.6 Article

Functionalized carbon microarrays platform for high sensitive detection of HIV-Tat peptide

Journal

RSC ADVANCES
Volume 5, Issue 80, Pages 65042-65047

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ra10214f

Keywords

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Funding

  1. FIU graduate school
  2. National Science Foundation [OISE 0934078, CMMI 0800525]
  3. GCOE Research from the Ministry of Education, Culture, Sports, Science and Technology, Japan
  4. Japan Society for the Promotion of Science (JSPS) [23246069]
  5. Ministry of Education, Malaysia [9017-00022]
  6. L'oreal Fellowship for Women in Science

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The detection of HIV disease at an early stage has significant clinical implications. We report the detection of HIV-TAT peptide on a functionalized three-dimensional carbon micropillar array platform. The sensor showed a linear relationship between HIV-TAT concentration and fluorescence intensity in the sub-nanomolar range with a detection limit of 50 pmol.

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