Circulating Th17 and Th1 cells expressing CD161 are associated with disease activity in rheumatoid arthritis

Functional niche of inflamed synovium for Th17-cell expansion and activation in rheumatoid arthritis: Implication to clinical therapeutics

(2012) Weijia Dong et al.   AUTOIMMUNITY REVIEWS

Distribution of regulatory T cells and interaction with dendritic cells in the synovium of rheumatoid arthritis

(2012) XQ E et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Increased circulating myeloid-derived suppressor cells correlated negatively with Th17 cells in patients with rheumatoid arthritis

(2012) Z Jiao et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis

(2011) Lorenzo Cosmi et al.   ARTHRITIS AND RHEUMATISM

Serum and synovial fluid levels of interleukin-17 in correlation with disease activity in patients with RA

(2011) Siham Ali Metawi et al.   CLINICAL RHEUMATOLOGY

Elevated Th22 Cells Correlated with Th17 Cells in Patients with Rheumatoid Arthritis

(2011) Lei Zhang et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Combined Treatment of Etanercept and MTX Reverses Th1/Th2, Th17/Treg Imbalance in Patients with Rheumatoid Arthritis

(2011) Chen Lina et al.   JOURNAL OF CLINICAL IMMUNOLOGY

The Pathogenesis of Rheumatoid Arthritis

(2011) Iain B. McInnes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Role of IL-17 in the Th1 systemic defects in rheumatoid arthritis through selective IL-12R 2 inhibition

(2010) M.-L. Toh et al.   ANNALS OF THE RHEUMATIC DISEASES

Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production

(2010) J. P. van Hamburg et al.   ARTHRITIS AND RHEUMATISM

LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

(2010) M. C. Genovese et al.   ARTHRITIS AND RHEUMATISM

CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC

(2010) Laura Maggi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Rheumatoid arthritis

(2010) David L Scott et al.   LANCET

Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment

(2010) K. Nistala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus

(2010) Kamini Shah et al.   ARTHRITIS RESEARCH & THERAPY

Frequency and phenotype of peripheral blood Th17 cells in ankylosing spondylitis and rheumatoid arthritis

(2009) Hui Shen et al.   ARTHRITIS AND RHEUMATISM

Late Developmental Plasticity in the T Helper 17 Lineage

(2009) Yun Kyung Lee et al.   IMMUNITY

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation

(2009) Melanie A. Kleinschek et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Garden of therapeutic delights: new targets in rheumatic diseases

(2009) Jean M Waldburger et al.   ARTHRITIS RESEARCH & THERAPY

Human interleukin 17–producing cells originate from a CD161+CD4+T cell precursor

(2008) Lorenzo Cosmi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction and effector functions of TH17 cells

(2008) Estelle Bettelli et al.   NATURE

TH-17 cells in rheumatoid arthritis

(2008) Shiva Shahrara et al.   ARTHRITIS RESEARCH & THERAPY