Association ofNLRP3andCARD8genetic polymorphisms with juvenile idiopathic arthritis in a Taiwanese population

Polimorphisms in Inflammasome Genes Are Involved in the Predisposition to Systemic Lupus Erythematosus

(2012) Alessandra Pontillo et al.   AUTOIMMUNITY

CARD8 rs2043211 (p.C10X) Polymorphism Is Not Associated with Disease Susceptibility or Cardiovascular Events in Spanish Rheumatoid Arthritis Patients

(2012) Mercedes García-Bermúdez et al.   DNA AND CELL BIOLOGY

The Q705K Polymorphism in NLRP3 Is a Gain-of-Function Alteration Leading to Excessive Interleukin-1β and IL-18 Production

(2012) Deepti Verma et al.   PLoS One

Body mass does not affect the remission of psoriatic arthritis patients on anti-TNF-α therapy

(2012) F Iannone et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Interleukin-17 and Th17 cells: From adult to juvenile arthritis-Now it is serious!

(2011) Pierre Miossec   ARTHRITIS AND RHEUMATISM

A phase II, multicenter, open-label study evaluating dosing and preliminary safety and efficacy of canakinumab in systemic juvenile idiopathic arthritis with active systemic features

(2011) Nicolino Ruperto et al.   ARTHRITIS AND RHEUMATISM

NLRP1 gene polymorphism influences gene transcription and is a risk factor for rheumatoid arthritis in Han Chinese

(2011) Jiangdong Sui et al.   ARTHRITIS AND RHEUMATISM

The pathogenesis of oligoarticular/polyarticular vs systemic juvenile idiopathic arthritis

(2011) Yu-Tsan Lin et al.   AUTOIMMUNITY REVIEWS

A multicentre, randomised, double-blind, placebo-controlled trial with the interleukin-1 receptor antagonist anakinra in patients with systemic-onset juvenile idiopathic arthritis (ANAJIS trial)

(2010) P. Quartier et al.   ANNALS OF THE RHEUMATIC DISEASES

Two SNPs inNLRP3gene are involved in the predisposition to type-1 diabetes and celiac disease in a pediatric population from northeast Brazil

(2010) A. Pontillo et al.   AUTOIMMUNITY

Genetic association between NLRP3 variants and Crohnʼs disease does not replicate in a large UK panel

(2010) Gregory J. Lewis et al.   INFLAMMATORY BOWEL DISEASES

Post-approval trials of new medicines: widening use or deepening knowledge? Analysis of 10 years of etanercept

(2010) JCF van Luijn et al.   SCANDINAVIAN JOURNAL OF RHEUMATOLOGY

Combined Polymorphisms in Genes Encoding the Inflammasome Components NALP3 and CARD8 Confer Susceptibility to Crohn's Disease in Swedish Men

(2009) Ida Schoultz et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

CARD8 p.C10X polymorphism is associated with inflammatory activity in early rheumatoid arthritis

(2009) A. Kastbom et al.   ANNALS OF THE RHEUMATIC DISEASES

Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis

(2009) Anne Hinks et al.   ARTHRITIS AND RHEUMATISM

Oligoarticular and polyarticular JIA: epidemiology and pathogenesis

(2009) Claudia Macaubas et al.   Nature Reviews Rheumatology

Interleukin-17–producing T cells are enriched in the joints of children with arthritis, but have a reciprocal relationship to regulatory T cell numbers

(2008) Kiran Nistala et al.   ARTHRITIS AND RHEUMATISM

Common variants in the NLRP3 region contribute to Crohn's disease susceptibility

(2008) Alexandra-Chloé Villani et al.   NATURE GENETICS