Small RNA binding to the lateral surface of Hfq hexamers and structural rearrangements upon mRNA target recognition

The functional Hfq-binding module of bacterial sRNAs consists of a double or single hairpin preceded by a U-rich sequence and followed by a 3' poly(U) tail

(2012) H. Ishikawa et al.   RNA

The crucial role of PNPase in the degradation of small RNAs that are not associated with Hfq

(2012) J. M. Andrade et al.   RNA

Despite Similar Binding to the Hfq Protein Regulatory RNAs Widely Differ in Their Competition Performance

(2011) Mikołaj Olejniczak   BIOCHEMISTRY

The influence of Escherichia coli Hfq mutations on RNA binding and sRNA•mRNA duplex formation in rpoS riboregulation

(2011) Taylor B. Updegrove et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

RNase E action at a distance: degradation of target mRNAs mediated by an Hfq-binding small RNA in bacteria

(2011) T. Morita et al.   GENES & DEVELOPMENT

Small RNA-induced mRNA degradation achieved through both translation block and activated cleavage

(2011) K. Prevost et al.   GENES & DEVELOPMENT

Cooperation of Escherichia coli Hfq hexamers in DsrA binding

(2011) W. Wang et al.   GENES & DEVELOPMENT

Competition among Hfq-binding small RNAs in Escherichia coli

(2011) Kyung Moon et al.   MOLECULAR MICROBIOLOGY

Structure of the spliceosomal U4 snRNP core domain and its implication for snRNP biogenesis

(2011) Adelaine K. W. Leung et al.   NATURE

Hfq and its constellation of RNA

(2011) Jörg Vogel et al.   NATURE REVIEWS MICROBIOLOGY

Structural insights into the dynamics and function of the C-terminus of the E. coli RNA chaperone Hfq

(2011) Mads Beich-Frandsen et al.   NUCLEIC ACIDS RESEARCH

Crystal structure of Hfq from Bacillus subtilis in complex with SELEX-derived RNA aptamer: insight into RNA-binding properties of bacterial Hfq

(2011) Tatsuhiko Someya et al.   NUCLEIC ACIDS RESEARCH

PolyU tail of rho-independent terminator of bacterial small RNAs is essential for Hfq action

(2011) Hironori Otaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for RNA 3′-end recognition by Hfq

(2011) Evelyn Sauer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Major role for mRNA binding and restructuring in sRNA recruitment by Hfq

(2011) T. J. Soper et al.   RNA

The stoichiometry of the Escherichia coli Hfq protein bound to RNA

(2011) T. B. Updegrove et al.   RNA

Functional organization of the Sm core in the crystal structure of human U1 snRNP

(2010) Gert Weber et al.   EMBO JOURNAL

RNAs actively cycle on the Sm-like protein Hfq

(2010) A. Fender et al.   GENES & DEVELOPMENT

C-Terminally Truncated Derivatives of Escherichia coli Hfq Are Proficient in Riboregulation

(2010) Anders Steno Olsen et al.   JOURNAL OF MOLECULAR BIOLOGY

Recognition of heptameric seed sequence underlies multi-target regulation by RybB small RNA in Salmonella enterica

(2010) Roberto Balbontín et al.   MOLECULAR MICROBIOLOGY

Hfq binding at RhlB-recognition region of RNase E is crucial for the rapid degradation of target mRNAs mediated by sRNAs in Escherichia coli

(2010) Yoshiki Ikeda et al.   MOLECULAR MICROBIOLOGY

Rfam: Wikipedia, clans and the "decimal" release

(2010) P. P. Gardner et al.   NUCLEIC ACIDS RESEARCH

Disruption of small RNA signaling caused by competition for Hfq

(2010) R. Hussein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence for an autonomous 5' target recognition domain in an Hfq-associated small RNA

(2010) K. Papenfort et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory RNAs in Bacteria

(2009) Lauren S. Waters et al.   CELL

Structure of Escherichia coli Hfq bound to polyriboadenylate RNA

(2009) T. M. Link et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple target regulation by small noncoding RNAs rewires gene expression at the post-transcriptional level

(2009) Kai Papenfort et al.   RESEARCH IN MICROBIOLOGY

Effect of Hfq on RprA−rpoSmRNA Pairing: Hfq−RNA Binding and the Influence of the 5′rpoSmRNA Leader Region†

(2008) Taylor Updegrove et al.   BIOCHEMISTRY

Small RNA Binding to 5′ mRNA Coding Region Inhibits Translational Initiation

(2008) Marie Bouvier et al.   MOLECULAR CELL

The rpoS mRNA leader recruits Hfq to facilitate annealing with DsrA sRNA

(2008) T. J. Soper et al.   RNA

Deep Sequencing Analysis of Small Noncoding RNA and mRNA Targets of the Global Post-Transcriptional Regulator, Hfq

(2008) Alexandra Sittka et al.   PLoS Genetics