MicroRNAs, wild-type and mutant p53: More questions than answers

An alternative mode of microRNA target recognition

(2012) Sung Wook Chi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

miR-17-92 cluster microRNAs confers tumorigenicity in multiple myeloma

(2011) Lijuan Chen et al.   CANCER LETTERS

An interview with Dr. Heiko Hermeking on his highly cited paper published inCell Cycle

(2011) Heiko Hermeking   CELL CYCLE

The code within the code: microRNAs target coding regions

(2011) Joshua J. Forman et al.   CELL CYCLE

MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function

(2011) S Donzelli et al.   CELL DEATH AND DIFFERENTIATION

miR-605joins p53 network to form a p53:miR-605:Mdm2 positive feedback loop in response to stress

(2011) Jiening Xiao et al.   EMBO JOURNAL

p53-dependent Induction ofPVT1and miR-1204

(2011) Anthony M. Barsotti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A p53/miRNA-34 axis regulates Snail1-dependent cancer cell epithelial–mesenchymal transition

(2011) Nam Hee Kim et al.   JOURNAL OF CELL BIOLOGY

p53 and its mutants in tumor cell migration and invasion

(2011) Patricia A. J. Muller et al.   JOURNAL OF CELL BIOLOGY

p53 regulates epithelial–mesenchymal transition through microRNAs targeting ZEB1 and ZEB2

(2011) Taewan Kim et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CPEB and two poly(A) polymerases control miR-122 stability and p53 mRNA translation

(2011) David M. Burns et al.   NATURE

p53 regulates epithelial–mesenchymal transition and stem cell properties through modulating miRNAs

(2011) Chun-Ju Chang et al.   NATURE CELL BIOLOGY

MicroRNAs can generate thresholds in target gene expression

(2011) Shankar Mukherji et al.   NATURE GENETICS

Direct targeting of Sec23a by miR-200s influences cancer cell secretome and promotes metastatic colonization

(2011) Manav Korpal et al.   NATURE MEDICINE

Evolution of microRNA diversity and regulation in animals

(2011) Eugene Berezikov   NATURE REVIEWS GENETICS

Non-coding RNAs in human disease

(2011) Manel Esteller   NATURE REVIEWS GENETICS

Myc overexpression brings out unexpected antiapoptotic effects of miR-34a

(2011) E Sotillo et al.   ONCOGENE

Dynamic epigenetic regulation of the microRNA-200 family mediates epithelial and mesenchymal transitions in human tumorigenesis

(2011) V Davalos et al.   ONCOGENE

Cellular Stress Induced Alterations in MicroRNA let-7a and let-7b Expression Are Dependent on p53

(2011) Anthony D. Saleh et al.   PLoS One

The emerging role of miR-200 family of MicroRNAs in epithelial-mesenchymal transition and cancer metastasis

(2011) Manav Korpal et al.   RNA Biology

Coding region

(2011) Eun Kyung Lee et al.   RNA Biology

A Parsimonious Model for Gene Regulation by miRNAs

(2011) S. Djuranovic et al.   SCIENCE

Conserved Regulation of p53 Network Dosage by MicroRNA–125b Occurs through Evolving miRNA–Target Gene Pairs

(2011) Minh T. N. Le et al.   PLoS Genetics

Capture of MicroRNA–Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling

(2011) Ashish Lal et al.   PLoS Genetics

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

A Genetic Defect in Exportin-5 Traps Precursor MicroRNAs in the Nucleus of Cancer Cells

(2010) Sonia A. Melo et al.   CANCER CELL

Modulation of the Vitamin D3 Response by Cancer-Associated Mutant p53

(2010) Perry Stambolsky et al.   CANCER CELL

Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development

(2010) Flavia Pichiorri et al.   CANCER CELL

The DLEU2/miR-15a/16-1 Cluster Controls B Cell Proliferation and Its Deletion Leads to Chronic Lymphocytic Leukemia

(2010) Ulf Klein et al.   CANCER CELL

Oncogenic Wip1 Phosphatase Is Inhibited by miR-16 in the DNA Damage Signaling Pathway

(2010) X. Zhang et al.   CANCER RESEARCH

p53-dependent repression of polo-like kinase-1 (PLK1)

(2010) Lynsey McKenzie et al.   CELL CYCLE

Checks and balances: E2F—microRNA crosstalk in cancer control

(2010) Stephan Emmrich et al.   CELL CYCLE

The ZEB/miR-200 feedback loop—a motor of cellular plasticity in development and cancer?

(2010) Simone Brabletz et al.   EMBO REPORTS

Systematic Proteome Analysis Identifies Transcription Factor YY1 as a Direct Target of miR-34a

(2010) Qing-Rong Chen et al.   JOURNAL OF PROTEOME RESEARCH

MicroRNA Functions in Stress Responses

(2010) Anthony K.L. Leung et al.   MOLECULAR CELL

Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing

(2010) Chanseok Shin et al.   MOLECULAR CELL

Negative Regulation of Tumor Suppressor p53 by MicroRNA miR-504

(2010) Wenwei Hu et al.   MOLECULAR CELL

Mammalian microRNAs predominantly act to decrease target mRNA levels

(2010) Huili Guo et al.   NATURE

TAp63 suppresses metastasis through coordinate regulation of Dicer and miRNAs

(2010) Xiaohua Su et al.   NATURE

Small RNA sorting: matchmaking for Argonautes

(2010) Benjamin Czech et al.   NATURE REVIEWS GENETICS

Desperately seeking microRNA targets

(2010) Marshall Thomas et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

p53 activates the PANK1/ miRNA-107 gene leading to downregulation of CDK6 and p130 cell cycle proteins

(2010) Levin Böhlig et al.   NUCLEIC ACIDS RESEARCH

Negative regulation of the tumor suppressor p53 gene by microRNAs

(2010) M Kumar et al.   ONCOGENE

P53-induced microRNA-107 inhibits HIF-1 and tumor angiogenesis

(2010) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-34a contributes to megakaryocytic differentiation of K562 cells independently of p53

(2009) F. Navarro et al.   BLOOD

MiR-122/Cyclin G1 Interaction Modulates p53 Activity and Affects Doxorubicin Sensitivity of Human Hepatocarcinoma Cells

(2009) F. Fornari et al.   CANCER RESEARCH

MicroRNA-145 Regulates OCT4, SOX2, and KLF4 and Represses Pluripotency in Human Embryonic Stem Cells

(2009) Na Xu et al.   CELL

A MicroRNA Imparts Robustness against Environmental Fluctuation during Development

(2009) Xin Li et al.   CELL

Blinded by the Light: The Growing Complexity of p53

(2009) Karen H. Vousden et al.   CELL

Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction

(2009) Ji Luo et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

MicroRNAs and Cancer: Short RNAs Go a Long Way

(2009) Andrea Ventura et al.   CELL

RETRACTED: A Pleiotropically Acting MicroRNA, miR-31, Inhibits Breast Cancer Metastasis

(2009) Scott Valastyan et al.   CELL

Origins and Mechanisms of miRNAs and siRNAs

(2009) Richard W. Carthew et al.   CELL

Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis

(2009) Hong-li Yan et al.   EMBO JOURNAL

MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells

(2009) Pedro M. Borralho et al.   FEBS Journal

MicroRNA-125b is a novel negative regulator of p53

(2009) M. T.N. Le et al.   GENES & DEVELOPMENT

Hyaluronan-CD44 Interaction with Protein Kinase Cϵ Promotes Oncogenic Signaling by the Stem Cell Marker Nanog and the Production of MicroRNA-21, Leading to Down-regulation of the Tumor Suppressor Protein PDCD4, Anti-apoptosis, and Chemotherapy Resistance in Breast Tumor Cells

(2009) Lilly Y. W. Bourguignon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-24 Inhibits Cell Proliferation by Targeting E2F2, MYC, and Other Cell-Cycle Genes via Binding to “Seedless” 3′UTR MicroRNA Recognition Elements

(2009) Ashish Lal et al.   MOLECULAR CELL

RETRACTED: Maturation of MicroRNA Is Hormonally Regulated by a Nuclear Receptor

(2009) Kaoru Yamagata et al.   MOLECULAR CELL

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

(2009) Ulrich Wellner et al.   NATURE CELL BIOLOGY

A TARBP2 mutation in human cancer impairs microRNA processing and DICER1 function

(2009) Sonia A Melo et al.   NATURE GENETICS

Small silencing RNAs: an expanding universe

(2009) Megha Ghildiyal et al.   NATURE REVIEWS GENETICS

Causes and consequences of microRNA dysregulation in cancer

(2009) Carlo M. Croce   NATURE REVIEWS GENETICS

Revisiting the principles of microRNA target recognition and mode of action

(2009) Peter Brodersen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Biogenesis of small RNAs in animals

(2009) V. Narry Kim et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis

(2009) Giulia Fontemaggi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

miR-200 Enhances Mouse Breast Cancer Cell Colonization to Form Distant Metastases

(2009) Derek M. Dykxhoorn et al.   PLoS One

Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation

(2009) T.-C. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DICER1 Mutations in Familial Pleuropulmonary Blastoma

(2009) D. A. Hill et al.   SCIENCE

Mutant p53 Gain-of-Function in Cancer

(2009) M. Oren et al.   Cold Spring Harbor Perspectives in Biology

p53-Responsive MicroRNAs 192 and 215 Are Capable of Inducing Cell Cycle Arrest

(2008) C. J. Braun et al.   CANCER RESEARCH

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

The Identification of MicroRNAs in a Genomically Unstable Region of Human Chromosome 8q24

(2008) K. Huppi et al.   MOLECULAR CANCER RESEARCH

Endogenous human microRNAs that suppress breast cancer metastasis

(2008) Sohail F. Tavazoie et al.   NATURE

The impact of microRNAs on protein output

(2008) Daehyun Baek et al.   NATURE

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation

(2008) Yvonne Tay et al.   NATURE

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

Transcriptional control of human p53-regulated genes

(2008) Todd Riley et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

miR-29 miRNAs activate p53 by targeting p85α and CDC42

(2008) Seong-Yeon Park et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence

(2008) J. J. Forman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA