Tolerability, Safety, and Quality of Life with Tapentadol Prolonged Release (PR) Compared with Oxycodone/Naloxone PR in Patients with Severe Chronic Low Back Pain with a Neuropathic Component: A Randomized, Controlled, Open-label, Phase 3b/4 Trial

Controlled-Release Oxycodone and Naloxone in the Treatment of Chronic Low Back Pain: A Placebo-Controlled, Randomized Study

(2016) C Cloutier et al.   Pain Research & Management

Practical Considerations for the Use of Tapentadol Prolonged Release for the Management of Severe Chronic Pain

(2015) Manuel J. Sánchez del Águila et al.   CLINICAL THERAPEUTICS

The global burden of low back pain: estimates from the Global Burden of Disease 2010 study

(2014) Damian Hoy et al.   ANNALS OF THE RHEUMATIC DISEASES

Ready Conversion of Patients with Well-Controlled, Moderate to Severe, Chronic Malignant Tumor–related Pain on Other Opioids to Tapentadol Extended Release

(2014) Keiichiro Imanaka et al.   CLINICAL DRUG INVESTIGATION

Opioids Compared With Placebo or Other Treatments for Chronic Low Back Pain

(2014) Luis Enrique Chaparro et al.   SPINE

Tapentadol Prolonged Release Versus Strong Opioids for Severe, Chronic Low Back Pain: Results of an Open-Label, Phase 3b Study

(2013) Rafael Gálvez et al.   ADVANCES IN THERAPY

Efficacy and safety of oral tapentadol extended release in Japanese and Korean patients with moderate to severe, chronic malignant tumor-related pain

(2013) Keiichiro Imanaka et al.   CURRENT MEDICAL RESEARCH AND OPINION

Effectiveness and safety of tapentadol prolonged release for severe, chronic low back pain with or without a neuropathic pain component: results of an open-label, phase 3b study

(2012) Ilona Steigerwald et al.   CURRENT MEDICAL RESEARCH AND OPINION

Efficacy and tolerability of tapentadol extended release (ER) in patients with chronic, painful diabetic peripheral neuropathy (DPN): results of a phase 3, randomized-withdrawal, placebo-controlled study

(2012) A. Vinik et al.   JOURNAL OF PAIN

Opioid-Induced Constipation: Challenges and Therapeutic Opportunities

(2011) Michael Camilleri   AMERICAN JOURNAL OF GASTROENTEROLOGY

Efficacy and safety of tapentadol prolonged release for chronic osteoarthritis pain and low back pain

(2010) Bernd Lange et al.   ADVANCES IN THERAPY

Efficacy and Safety of Tapentadol Extended Release Compared with Oxycodone Controlled Release for the Management of Moderate to Severe Chronic Pain Related to Osteoarthritis of the Knee

(2010) Marc Afilalo et al.   CLINICAL DRUG INVESTIGATION

Safety and efficacy of tapentadol ER in patients with painful diabetic peripheral neuropathy: results of a randomized-withdrawal, placebo-controlled trial

(2010) Sherwyn Schwartz et al.   CURRENT MEDICAL RESEARCH AND OPINION

Efficacy and safety of tapentadol extended release for the management of chronic low back pain: results of a prospective, randomized, double-blind, placebo- and active-controlled Phase III study

(2010) Robert Buynak et al.   EXPERT OPINION ON PHARMACOTHERAPY

Neuropathic pain: diagnosis, pathophysiological mechanisms, and treatment

(2010) Ralf Baron et al.   LANCET NEUROLOGY

The burden of neuropathic pain: A systematic review and meta-analysis of health utilities

(2010) Alissa H. Doth et al.   PAIN

Long-term Safety and Tolerability of Tapentadol Extended Release for the Management of Chronic Low Back Pain or Osteoarthritis Pain

(2010) James E. Wild et al.   Pain Practice

Nausea and Vomiting Side Effects with Opioid Analgesics during Treatment of Chronic Pain: Mechanisms, Implications, and Management Options

(2009) Frank Porreca et al.   PAIN MEDICINE

Assessment and diagnosis of neuropathic pain

(2009) Ralf Baron et al.   Current Opinion in Supportive and Palliative Care

Fixed-ratio combination oxycodone/naloxone compared with oxycodone alone for the relief of opioid-induced constipation in moderate-to-severe noncancer pain

(2008) K. Simpson et al.   CURRENT MEDICAL RESEARCH AND OPINION

Analgesic Efficacy and Safety of Oxycodone in Combination With Naloxone as Prolonged Release Tablets in Patients With Moderate to Severe Chronic Pain

(2008) Dana Vondrackova et al.   JOURNAL OF PAIN

The Prevalence, Severity, and Impact of Opioid-Induced Bowel Dysfunction: Results of a US and European Patient Survey (PROBE 1)

(2008) Timothy J. Bell et al.   PAIN MEDICINE

Prevalence of chronic pain with neuropathic characteristics in the general population

(2007) Didier Bouhassira et al.   PAIN