Current, new and future treatments of osteoporosis

Prospects for osteoprogenitor stem cells in fracture repair and osteoporosis

(2010) Gregory A Clines   Current Opinion in Organ Transplantation

Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength

(2010) Michael S Ominsky et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Molecular biology of bone remodeling: Implications for new therapeutic targets for osteoporosis

(2010) J. Chris Gallagher et al.   MATURITAS

Anabolic Therapies

(2010) Nancy E. Lane et al.   Current Osteoporosis Reports

A novel carborane analog, BE360, with a carbon-containing polyhedral boron-cluster is a new selective estrogen receptor modulator for bone

(2009) Michiko Hirata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Effect of the Cathepsin K Inhibitor Odanacatib on Bone Resorption Biomarkers in Healthy Postmenopausal Women: Two Double-Blind, Randomized, Placebo-Controlled Phase I Studies

(2009) S A Stoch et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Selective androgen receptor modulators as function promoting therapies

(2009) Shalender Bhasin et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Clinical assessment of fracture risk and novel therapeutic strategies to combat osteoporosis

(2009) Mark S. Nanes et al.   FERTILITY AND STERILITY

Bazedoxifene effects on the reproductive tract in postmenopausal women at risk for osteoporosis

(2009) JoAnn V. Pinkerton et al.   MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY

Denosumab in Men Receiving Androgen-Deprivation Therapy for Prostate Cancer

(2009) Matthew R. Smith et al.   NEW ENGLAND JOURNAL OF MEDICINE

Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis

(2009) Steven R. Cummings et al.   NEW ENGLAND JOURNAL OF MEDICINE

Pharmacologic treatment to prevent fractures: from markers to patients

(2009) Steven R. Cummings   OSTEOPOROSIS INTERNATIONAL

The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K

(2008) Jacques Yves Gauthier et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Effect of denosumab on bone density and turnover in postmenopausal women with low bone mass after long-term continued, discontinued, and restarting of therapy: A randomized blinded phase 2 clinical trial

(2008) Paul D. Miller et al.   BONE

l-Carnitine Fumarate and Isovaleryl-l-Carnitine Fumarate Accelerate the Recovery of Bone Volume/Total Volume Ratio after Experimetally Induced Osteoporosis in Pregnant Mice

(2008) N. Patano et al.   CALCIFIED TISSUE INTERNATIONAL

Lrp5 Controls Bone Formation by Inhibiting Serotonin Synthesis in the Duodenum

(2008) Vijay K. Yadav et al.   CELL

Combination of bone tissue engineering and BMP-2 gene transfection promotes bone healing in osteoporotic rats

(2008) Youchao Tang et al.   CELL BIOLOGY INTERNATIONAL

Receptor Activator of Nuclear Factor κB Ligand and Osteoprotegerin Regulation of Bone Remodeling in Health and Disease

(2008) Ann E. Kearns et al.   ENDOCRINE REVIEWS

Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Efficacy of Bazedoxifene in Reducing New Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis: Results From a 3-Year, Randomized, Placebo-, and Active-Controlled Clinical Trial*

(2008) Stuart L Silverman et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Comparison of the Effect of Denosumab and Alendronate on BMD and Biochemical Markers of Bone Turnover in Postmenopausal Women With Low Bone Mass: A Randomized, Blinded, Phase 3 Trial*

(2008) Jacques P Brown et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis*

(2008) Xiaodong Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Randomized Trial of Denosumab in Patients Receiving Adjuvant Aromatase Inhibitors for Nonmetastatic Breast Cancer

(2008) Georgiana K. Ellis et al.   JOURNAL OF CLINICAL ONCOLOGY

Pharmacological Topics of Bone Metabolism: Antiresorptive Microbial Compounds That Inhibit Osteoclast Differentiation, Function, and Survival

(2008) Je-Tae Woo et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Targeting the Wnt signaling pathway to augment bone formation

(2008) Mohammad Shahnazari et al.   Current Osteoporosis Reports

Cathepsin K inhibitors prevent matrix-derived growth factor degradation by human osteoclasts

(2007) Karen Fuller et al.   BONE

Dual effect of strontium ranelate: Stimulation of osteoblast differentiation and inhibition of osteoclast formation and resorption in vitro

(2007) Edith Bonnelye et al.   BONE

Adrenomedullin is anti-apoptotic in osteoblasts through CGRP1 receptors and MEK-ERK pathway

(2007) Benjamin Uzan et al.   JOURNAL OF CELLULAR PHYSIOLOGY