Focal adhesion kinase and reactive oxygen species contribute to the persistent fibrotic phenotype of lesional scleroderma fibroblasts

Long-Term N-Acetylcysteine Therapy in Systemic Sclerosis Interstitial Lung Disease: A Retrospective Study

(2017) E. Rosato et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

Efficacy of inhaled N-acetylcysteine monotherapy in patients with early stage idiopathic pulmonary fibrosis

(2012) SAKAE HOMMA et al.   RESPIROLOGY

Inhibition of focal adhesion kinase prevents experimental lung fibrosis and myofibroblast formation

(2011) David Lagares et al.   ARTHRITIS AND RHEUMATISM

Focal adhesion kinase inhibitors are potent anti-angiogenic agents

(2011) Miguel A. Cabrita et al.   Molecular Oncology

Mechanical Tension Increases CCN2/CTGF Expression and Proliferation in Gingival Fibroblasts via a TGFβ-Dependent Mechanism

(2011) Fen Guo et al.   PLoS One

Expression of integrin  1 by fibroblasts is required for tissue repair in vivo

(2010) S. Liu et al.   JOURNAL OF CELL SCIENCE

ALK5 Inhibition Blocks TGFβ-induced CCN2 Expression in Gingival Fibroblasts

(2010) K. Thompson et al.   JOURNAL OF DENTAL RESEARCH

Specific shRNA targeting ofFAKinfluenced collagen metabolism in rat hepatic stellate cells

(2010) Zhi-Na Dun   WORLD JOURNAL OF GASTROENTEROLOGY

Rac1 Expression by Fibroblasts Is Required for Tissue Repair in Vivo

(2009) Shangxi Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

N-acetylcysteine inhibits alveolar epithelial-mesenchymal transition

(2009) V. M. Felton et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Loss of β1 integrin in mouse fibroblasts results in resistance to skin scleroderma in a mouse model

(2009) Shangxi Liu et al.   ARTHRITIS AND RHEUMATISM

N-acetyl-l-cysteine inhibits TGF-β1-induced profibrotic responses in fibroblasts

(2009) Hisatoshi Sugiura et al.   PULMONARY PHARMACOLOGY & THERAPEUTICS

Tissue stiffness, latent TGF-β1 Activation, and mechanical signal transduction: Implications for the pathogenesis and treatment of fibrosis

(2009) Boris Hinz   Current Rheumatology Reports

Targeting the TGFβ, endothelin-1 and CCN2 axis to combat fibrosis in scleroderma

(2008) Andrew Leask   CELLULAR SIGNALLING

Loss of protein kinase C  results in impaired cutaneous wound closure and myofibroblast function

(2008) A. Leask et al.   JOURNAL OF CELL SCIENCE

Fibroblast adhesion results in the induction of a matrix remodeling gene expression program

(2008) L KENNEDY et al.   MATRIX BIOLOGY

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY