Article
Biochemistry & Molecular Biology
Zijian Chen, Panyun Wu, Jiangang Wang, Pengfei Chen, Zhenfei Fang, Fei Luo
Summary: The comprehensive meta-analysis of randomized controlled trials showed that statin therapy does not reduce cancer incidence or mortality while protecting the cardiovascular system.
LIPIDS IN HEALTH AND DISEASE
(2023)
Review
Oncology
Yi Chen, Jianshu Zhang, Yin Zhang, Linlin Zhu
Summary: This systematic review and meta-analysis evaluated the association between statin use and gastric cancer. The use of statins was associated with a significantly lower risk of gastric cancer, as well as lower all-cause mortality and cancer-specific mortality of gastric cancer. However, more well-designed, large-scale studies and randomized clinical trials are needed to confirm the effect of statins on gastric cancer in future clinical practice.
Review
Immunology
Jian Deng, Mengsi Liu, Ruoyi Xiao, Jin Wang, Xibei Liao, Zhen Ye, Zhen Sun
Summary: The study found no overall association between pSS and the risk or mortality of breast cancer, but there were geographical differences; pSS patients in European countries had a lower risk of breast cancer, while those in Asia and Argentina had a higher risk.
FRONTIERS IN IMMUNOLOGY
(2022)
Article
Environmental Sciences
VA. Florez-Garcia, EC. Guevara-Romero, MM. Hawkins, LE. Bautista, TE. Jenson, J. Yu, AE. Kalkbrenner
Summary: This study evaluated the association between cadmium exposure and breast cancer incidence in women. The meta-analysis found that exposure to higher levels of cadmium increased the risk of breast cancer. Different exposure routes showed varied results, with dietary cadmium not linked to elevated risk but biomarker-based studies showing a non-significant increased risk. Rating: 8 out of 10
ENVIRONMENTAL RESEARCH
(2023)
Review
Oncology
Rong Wang, Hong-xin Yang, Jie Chen, Jian-jun Huang, Qing Lv
Summary: This meta-analysis suggests that breast surgery (including modified radical mastectomy and breast-conserving surgery) combined with radiotherapy may be the optimal surgical approach in patients with occult breast cancer. Radiotherapy does not prolong the time of distant metastasis and local recurrences.
FRONTIERS IN ONCOLOGY
(2023)
Review
Oncology
Jing Lin, Rongzu Tu, Zhai'e Lu
Summary: The study suggests that women with prediabetes may not have an increased risk of breast cancer compared to women with normoglycemia.
FRONTIERS IN ONCOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Iad Alhallak, Hakan Paydak, Jawahar L. Mehta
Summary: Studies have shown that statins can reduce COVID-19 mortality in hospitalized patients. This paper evaluates the studies and reviews the mechanism of how statins modulate COVID-19 severity.
CURRENT PROBLEMS IN CARDIOLOGY
(2023)
Review
Clinical Neurology
Ming-Chia Lee, Tzu-Rong Peng, Chih-Hsin Lee, Jann-Yuan Wang, Jen-Ai Lee, Shih-Ming Chen, Jeng-Chuan Shiang
Summary: This meta-analysis revealed that statin use was not associated with depression. However, there was high heterogeneity observed between identified studies, and results were inconsistent in the subgroups of studies published before 2013.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Review
Oncology
Sin-Hye Park, Tung Hoang, Jeongseon Kim
Summary: This study examines the relationship between dietary factors and breast cancer prognosis among breast cancer survivors through systematic review and meta-analysis. It finds that unhealthy dietary patterns such as beer and saturated fat intake may worsen breast cancer prognosis, while supplementation of most vitamins is beneficial. The study suggests that developing dietary guidelines based on these findings could improve the prognosis for breast cancer survivors.
Review
Medicine, Research & Experimental
Tong Wu, Zhenhua Tong, Tianshu Ren, Danni Xie, Xue Sun
Summary: This meta-analysis demonstrated that the use of erythropoiesis-stimulating agents (ESAs) increases the risk of mortality and thrombo-vascular adverse events in breast cancer patients, while effectively improving anemia symptoms and reducing transfusion requirements.
CLINICAL AND EXPERIMENTAL MEDICINE
(2023)
Article
Oncology
Mihong Choi, Jiyeon Han, Bo Ram Yang, Myoung-jin Jang, Miso Kim, Dae-Won Lee, Tae-Yong Kim, Seock-Ah Im, Han-Byoel Lee, Hyeong-Gon Moon, Wonshik Han, Dong-Young Noh, Kyung-Hun Lee
Summary: Insulin or statin use prior to breast cancer diagnosis is associated with increased all-cause mortality. Subsequent analysis suggests metformin or statin use may be protective in patients with ER-negative disease, warranting further studies.
CANCER RESEARCH AND TREATMENT
(2021)
Review
Pharmacology & Pharmacy
Daniele Pastori, Francesco Baratta, Arianna Di Rocco, Alessio Farcomeni, Maria Del Ben, Francesco Angelico, Francesco Violi, Pasquale Pignatelli, Gregory Y. H. Lip
Summary: This meta-analysis found that in AF patients, statin therapy was associated with a 41% reduction in all-cause mortality and a 25% reduction in cardiovascular mortality. Randomized clinical trials in AF patients are needed to further confirm these findings and clarify specific LDL cholesterol targets for AF.
PHARMACOLOGICAL RESEARCH
(2021)
Review
Multidisciplinary Sciences
Pauline Luczynski, Philip Poulin, Kamila Romanowski, James C. Johnston
Summary: People with tuberculosis have an increased risk of developing cancer, especially lung cancer, particularly within the first year following tuberculosis diagnosis. Further research is needed to develop effective screening and early detection strategies.
Review
Medicine, General & Internal
Kamal Awad, Maged Mohammed, Mahmoud Mohamed Zaki, Abdelrahman I. Abushouk, Gregory Y. H. Lip, Michael J. Blaha, Carl J. Lavie, Peter P. Toth, J. Wouter Jukema, Naveed Sattar, Maciej Banach
Summary: Statin therapy in older people for primary prevention of cardiovascular disease is associated with significantly lower risks of all-cause mortality, CVD death, and stroke, but not with myocardial infarction. The observational findings support the need for further trials to test the benefits of statins in individuals above 75 years of age.
Article
Cardiac & Cardiovascular Systems
Ibadete Bytyci, Peter E. Penson, Dimitri P. Mikhailidis, Nathan D. Wong, Adrian Hernandez, Amirhossein Sahebkar, Paul D. Thompson, Mohsen Mazidi, Jacek Rysz, Daniel Pella, Zeljko Reiner, Peter P. Toth, Maciej Banach
Summary: This meta-analysis estimated the overall prevalence of statin intolerance (SI) and found that female gender, hypothyroidism, high statin dose, advanced age, antiarrhythmics, and obesity are the main risk factors for SI.
EUROPEAN HEART JOURNAL
(2022)
Review
Food Science & Technology
Qi Cui, Yang Xia, Qijun Wu, Qing Chang, Kaijun Niu, Yuhong Zhao
Summary: Food frequency questionnaires (FFQs) are commonly used tools for assessing dietary intake. This study comprehensively evaluated the validity of FFQs and found that they are suitable for assessing overall dietary intake in nutritional epidemiological studies.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Article
Environmental Sciences
Si-Tian Zang, Jie Luan, Ling Li, Hui-Xin Yu, Qi-Jun Wu, Qing Chang, Yu-Hong Zhao
Summary: The meta-analysis found a positive association between long-term exposure to outdoor air pollution and COVID-19 incidence and mortality. Short-term exposure to air pollutants was also positively associated with COVID-19 incidence. Reducing pollutant levels may help alleviate the burden of the pandemic.
ENVIRONMENTAL RESEARCH
(2022)
Article
Nutrition & Dietetics
Qi Cui, Yang Xia, Yashu Liu, Yifei Sun, Kang Ye, Wenjie Li, Qijun Wu, Qing Chang, Yuhong Zhao
Summary: This study evaluated the reproducibility and validity of the Food Frequency Questionnaire (FFQ) for residents in northeast China. The findings demonstrated that the FFQ is reliable and valid for assessing the intake of most foods and nutrients.
BRITISH JOURNAL OF NUTRITION
(2023)
Article
Public, Environmental & Occupational Health
Qing Chang, Qijun Wu, Yang Xia, Hehua Zhang, Shanyan Gao, Yixiao Zhang, Yuan Yuan, Jing Jiang, Hongbin Qiu, Jing Li, Chunming Lu, Chao Ji, Xin Xu, Donghui Huang, Huixu Dai, Zhiying Zhao, Hang Li, Xiaoying Li, Xiaosong Qin, Caigang Liu, Xiaoyu Ma, Xinrui Xu, Da Yao, Yuhong Zhao
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Ming-Hui Sun, Ting-Ting Gong, He-Li Xu, Jia-Li Yin, Hui-Juan Yang, Bing-Jie Zou, Hong-Yu Chen, Zong-Da Du, Ran Wang, Shi Yan, Jin Xu, Fang-Hua Liu, Ming-Li Sun, Song Gao, Yu-Hong Zhao, Qi-Jun Wu
Summary: In a prospective cohort study in China, the relationship between dietary antioxidant vitamin intake and ovarian cancer (OC) survival was evaluated. The study found that higher intake of vitamin C and beta-carotene was associated with improved survival in OC patients. However, intake of retinol, vitamin A, vitamin E, and alpha-carotene showed no association with OC survival.
Article
Nutrition & Dietetics
Jun-Qi Zhao, Qi-Peng Ma, Yi-Fan Wei, Gang Zheng, Bing-Jie Zou, Zong-Da Du, Song Gao, Shi Yan, Xue Qin, Ting-Ting Gong, Yu-Hong Zhao, Qi-Jun Wu
Summary: This study evaluated the associations between nutrients-rich food (NRF) index scores and overall survival (OS) in ovarian cancer (OC) patients. The results showed that higher NRF index scores were correlated with improved OS, with a linear trend. Interestingly, a non-linear association was also observed between NRF6.3 index score and OC survival. This study is important as it reveals the impact of diet quality on the survival of OC patients.
Article
Nutrition & Dietetics
Gang Zheng, Ting-Ting Gong, Qi-Peng Ma, Yi-Fan Wei, Zong-Da Du, Jun-Qi Zhao, Bing-Jie Zou, Shi Yan, Fang-Hua Liu, Ming-Li Sun, Qian Xiao, Song Gao, Qi-Jun Wu, Yu -Hong Zhao
Summary: This study investigated the association between overall macronutrient quality and the survival of patients with ovarian cancer, and found that intake of high-quality macronutrients was associated with improved survival among females with OC, especially for those with energy imbalance.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2023)
Article
Medicine, General & Internal
Shuang Zhang, Shu-Xin Liu, Qi-Jun Wu, Zhi-Hong Wang, Hong Liu, Cui Dong, Ting-Ting Kuai, Lian-Lian You, Jia Xiao
Summary: This cross-sectional study involving 741 Chinese maintenance hemodialysis patients found an inverse association between dietary fiber intake and poor sleep quality. Higher intake of total dietary fiber, total insoluble dietary fiber, and soluble dietary fiber in vegetables were associated with a lower prevalence of poor sleep quality.
ANNALS OF MEDICINE
(2023)
Review
Medicine, Research & Experimental
Huan-Huan Chen, Yi-Xiao Zhang, Jia-Le Lv, Yu-Yang Liu, Jing-Yi Guo, Lu Zhao, Yu-Xin Nan, Qi-Jun Wu, Yu-Hong Zhao
Summary: Poor control of metabolic diseases can lead to kidney injury, including microalbuminuria, renal insufficiency, and chronic kidney disease. The precise mechanisms of renal injury caused by metabolic diseases remain unclear. This literature review examines the role of histone deacetylases known as SIRTs in regulating the pathogenesis of metabolic disease-related kidney disorders and discusses their potential as biomarkers and therapeutic targets.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Article
Environmental Sciences
Song Gao, Bing-Jie Zou, Su Shi, Yi-Fan Wei, Zong-Da Du, Gang Zheng, Rang Wang, Jia-Li Yin, Jun-Qi Zhao, Shi Yan, Xue Qin, Qian Xiao, Ting-Ting Gong, Ren-Jie Chen, Yu-Hong Zhao, Qi-Jun Wu
Summary: Recent evidence suggests that particles with a diameter of 2.5 micrometers or less (PM2.5) may impact the survival of ovarian cancer patients. The oxidative balance score (OBS), which takes into account diet-lifestyle factors, can estimate individuals' antioxidant exposure status and potentially affect cancer prognosis. In this study, we aimed to investigate the roles of PM2.5, OBS, and their interaction in the prognosis of ovarian cancer.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2023)
Article
Nutrition & Dietetics
Zongda Du, Tingting Gong, Yifan Wei, Gang Zheng, Junqi Zhao, Bingjie Zou, Xue Qin, Shi Yan, Fanghua Liu, Qian Xiao, Qijun Wu, Song Gao, Yuhong Zhao
Summary: A prospective cohort study found that higher intake of purine was associated with a lower risk of ovarian cancer mortality. There was a curving relationship between total purine intake and ovarian cancer mortality, with greater decrease in risk at higher intake levels. These findings provide valuable insights into the role of purine in the development and progression of ovarian cancer.
Article
Medicine, General & Internal
Jian-Zeng Guo, Qian Xiao, Lang Wu, Fa Chen, Jia-Li Yin, Xue Qin, Ting-Ting Gong, Qi-Jun Wu
Summary: In this study, a bidirectional Mendelian randomization analysis was conducted to investigate the relationship between Parkinson's disease (PD) and ovarian cancer (OC) using genetic markers as a proxy. The results did not observe a strong genetic association between PD and OC overall. However, there was a suggestive inverse association between high grade serous OC and reduced PD risk.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Medicine, General & Internal
Ying-Jun Huo, Xiao-Ying Li, Meng Zhang, Chang Gao, Qian Xiao, Yu-Hong Zhao, Song Gao, Ting-Ting Gong, Qi-Jun Wu
Summary: This umbrella review comprehensively and quantitatively evaluated the associations between single nucleotide polymorphisms (SNPs) and ovarian cancer (OC) risk. The results revealed associations between SNPs and OC risk, with strong cumulative evidence for six SNPs (eight genetic models).
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Environmental Sciences
Yi-Zi Li, Shu-Hong Huang, Su Shi, Wen-Xiao Chen, Yi-Fan Wei, Bing-Jie Zou, Wei Yao, Lu Zhou, Fang-Hua Liu, Song Gao, Shi Yan, Xue Qin, Yu-Hong Zhao, Ren-Jie Chen, Ting-Ting Gong, Qi-Jun Wu
Summary: This prospective cohort study showed that long-term exposure to PM2.5 particles was significantly associated with increased mortality among ovarian cancer patients. Specifically, higher PM2.5 exposure levels in the year prior to diagnosis were linked to an increased risk of all-cause mortality. The lag effect of 1-6 years of long-term PM2.5 exposure was also observed. Additionally, significant interactions were found between immunological indicators, solid fuel use for cooking, and ambient PM2.5 concentrations.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Review
Public, Environmental & Occupational Health
Xin-Yu Li, Gang Li, Ting-Ting Gong, Jia-Le Lv, Chang Gao, Fang-Hua Liu, Yu-Hong Zhao, Qi-Jun Wu
Summary: This umbrella review evaluated and synthesized previously published systematic reviews and meta-analyses on the association between non-genetic factors and cervical cancer risk. The findings indicate a strong association between oral contraceptive use, Chlamydia trachomatis infection, and increased CC risk. There are also several other risk factors with suggestive or highly suggestive evidence.
INTERNATIONAL JOURNAL OF PUBLIC HEALTH
(2023)