Impact of Maternal Diet on the Epigenome during In Utero Life and the Developmental Programming of Diseases in Childhood and Adulthood

Exposure to aflatoxin B1in uterois associated with DNA methylation in white blood cells of infants in The Gambia

(2015) Hector Hernandez-Vargas et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Function and information content of DNA methylation

(2015) Dirk Schübeler   NATURE

Considering Maternal Dietary Modulators for Epigenetic Regulation and Programming of the Fetal Epigenome

(2015) Abalo Chango et al.   Nutrients

Independent genomewide screens identify the tumor suppressor VTRNA2-1 as a human epiallele responsive to periconceptional environment

(2015) Matt J Silver et al.   GENOME BIOLOGY

Embryo number and periconceptional undernutrition in the sheep have differential effects on adrenal epigenotype, growth, and development

(2014) Olivia Williams-Wyss et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions

(2014) Hao Wu et al.   CELL

In Utero Undernutrition in Male Mice Programs Liver Lipid Metabolism in the Second-Generation Offspring Involving Altered Lxra DNA Methylation

(2014) Débora Martínez et al.   Cell Metabolism

Tet3 and DNA Replication Mediate Demethylation of Both the Maternal and Paternal Genomes in Mouse Zygotes

(2014) Li Shen et al.   Cell Stem Cell

Maternal diet–induced microRNAs and mTOR underlie β cell dysfunction in offspring

(2014) Emilyn U. Alejandro et al.   JOURNAL OF CLINICAL INVESTIGATION

Cancer Epigenetics: Tumor Heterogeneity, Plasticity of Stem-like States, and Drug Resistance

(2014) Hariharan Easwaran et al.   MOLECULAR CELL

Identification of master genes involved in liver key functions through transcriptomics and epigenomics of methyl donor deficiency in rat: Relevance to nonalcoholic liver disease

(2014) Gaili Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

High Fat Diet and In Utero Exposure to Maternal Obesity Disrupts Circadian Rhythm and Leads to Metabolic Programming of Liver in Rat Offspring

(2014) Sarah J. Borengasser et al.   PLoS One

Identifying placental epigenetic alterations in an intrauterine growth restriction (IUGR) rat model induced by gestational protein deficiency

(2014) Stella Marie Reamon-Buettner et al.   REPRODUCTIVE TOXICOLOGY

In utero undernourishment perturbs the adult sperm methylome and intergenerational metabolism

(2014) E. J. Radford et al.   SCIENCE

Early Life Nutrition, Epigenetics and Programming of Later Life Disease

(2014) Mark Vickers   Nutrients

Modulation of DNA methylation states and infant immune system by dietary supplementation with ω-3 PUFA during pregnancy in an intervention study

(2013) Ho-Sun Lee et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Early environmental factors, alteration of epigenetic marks and metabolic disease susceptibility

(2013) B. Portha et al.   BIOCHIMIE

Transgenerational effects of prenatal exposure to the 1944-45 Dutch famine

(2013) MVE Veenendaal et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease

(2013) Valentina Medici et al.   Epigenetics

Transgenerational developmental programming

(2013) Catherine E. Aiken et al.   HUMAN REPRODUCTION UPDATE

Early-life prevention of non-communicable diseases

(2013) John M Balbus et al.   LANCET

Nutritional models of foetal programming and nutrigenomic and epigenomic dysregulations of fatty acid metabolism in the liver and heart

(2013) Jean-Louis Guéant et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Intrauterine calorie restriction affects placental DNA methylation and gene expression

(2013) Pao-Yang Chen et al.   PHYSIOLOGICAL GENOMICS

Prenatal Ethanol Exposure Causes Glucose Intolerance with Increased Hepatic Gluconeogenesis and Histone Deacetylases in Adult Rat Offspring: Reversal by Tauroursodeoxycholic Acid

(2013) Xing-Hai Yao et al.   PLoS One

Folate and fetal programming: a play in epigenomics?

(2013) Jean-Louis Guéant et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Interplay between polymorphisms and methylation in the H19/IGF2 gene region may contribute to obesity in Mexican-American children

(2013) M. A. Hernández-Valero et al.   Journal of Developmental Origins of Health and Disease

Folate in pregnancy and imprinted gene and repeat element methylation in the offspring

(2012) Paul Haggarty et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

MicroRNA-130b and microRNA-374b mediate the effect of maternal dietary protein on offspring lipid metabolism in Meishan pigs

(2012) Shifeng Pan et al.   BRITISH JOURNAL OF NUTRITION

An unbalanced maternal diet in pregnancy associates with offspring epigenetic changes in genes controlling glucocorticoid action and foetal growth

(2012) Amanda J. Drake et al.   CLINICAL ENDOCRINOLOGY

Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans

(2012) Xinyin Jiang et al.   FASEB JOURNAL

A maternal high-fat diet modulates fetal SIRT1 histone and protein deacetylase activity in nonhuman primates

(2012) Melissa A. Suter et al.   FASEB JOURNAL

DNA methylation profiling at imprinted loci after periconceptional micronutrient supplementation in humans: results of a pilot randomized controlled trial

(2012) Wendy N. Cooper et al.   FASEB JOURNAL

Maternal nutrition and offspring’s adulthood NCD’s: a review

(2012) Yael Pasternak et al.   Journal of Maternal-Fetal & Neonatal Medicine

Sirtuin 1 and Sirtuin 3: Physiological Modulators of Metabolism

(2012) Ruben Nogueiras et al.   PHYSIOLOGICAL REVIEWS

Homocysteine Imbalance: a Pathological Metabolic Marker

(2012) Kevin L. Schalinske et al.   Advances in Nutrition

Chronic prenatal ethanol exposure increases adiposity and disrupts pancreatic morphology in adult guinea pig offspring

(2012) C C Dobson et al.   Nutrition & Diabetes

An Unbiased Assessment of the Role of Imprinted Genes in an Intergenerational Model of Developmental Programming

(2012) Elizabeth J. Radford et al.   PLoS Genetics

An Alu Element–Associated Hypermethylation Variant of the POMC Gene Is Associated with Childhood Obesity

(2012) Peter Kuehnen et al.   PLoS Genetics

Nutrition, Epigenetics, and Metabolic Syndrome

(2011) Junjun Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

SIRT1: roles in aging and cancer

(2011) Eun-Joo Kim et al.   BMB Reports

Epigenetics in Alzheimers Disease: a Focus on DNA Modifications

(2011) Natacha Coppieters et al.   CURRENT PHARMACEUTICAL DESIGN

Epigenetic Gene Promoter Methylation at Birth Is Associated With Child's Later Adiposity

(2011) K. M. Godfrey et al.   DIABETES

Gestational low protein diet in the rat mediatesIgf2gene expression in male offspring via altered hepatic DNA methylation

(2011) Li Gong et al.   Epigenetics

Maternal protein restriction during pregnancy induces CCAAT/enhancer-binding protein (C/EBPβ) expression through the regulation of histone modification at its promoter region in female offspring rat skeletal muscle

(2011) Shasha Zheng et al.   Epigenetics

Methylation variation atIGF2differentially methylated regions and maternal folic acid use before and during pregnancy

(2011) Cathrine Hoyo et al.   Epigenetics

Maternal methyl-donor supplementation induces prolonged murine offspring colitis susceptibility in association with mucosal epigenetic and microbiomic changes

(2011) Tiffany D. Schaible et al.   HUMAN MOLECULAR GENETICS

Moderate Caloric Restriction during Gestation in Rats Alters Adipose Tissue Sympathetic Innervation and Later Adiposity in Offspring

(2011) Ana Paula García et al.   PLoS One

Allele-Specific, Age-Dependent and BMI-Associated DNA Methylation of Human MCHR1

(2011) Stefanie Stepanow et al.   PLoS One

Progressive, Transgenerational Changes in Offspring Phenotype and Epigenotype following Nutritional Transition

(2011) Graham C. Burdge et al.   PLoS One

Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets

(2011) I. Sandovici et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effect of maternal diet on the epigenome: implications for human metabolic disease

(2011) Karen A. Lillycrop   PROCEEDINGS OF THE NUTRITION SOCIETY

Prenatal exposure to ethanol: A specific effect on the H19 gene in sperm

(2011) Christelle Stouder et al.   REPRODUCTIVE TOXICOLOGY

Maternal High-Fat Diet Alters Methylation and Gene Expression of Dopamine and Opioid-Related Genes

(2010) Zivjena Vucetic et al.   ENDOCRINOLOGY

LINE-1 DNA methylation is inversely correlated with cord plasma homocysteine in man: A preliminary study

(2010) Anthony A. Fryer et al.   Epigenetics

Overview of homocysteine and folate metabolism. With special references to cardiovascular disease and neural tube defects

(2010) Henk J. Blom et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE

Maternal dietary choline deficiency alters angiogenesis in fetal mouse hippocampus

(2010) M. G. Mehedint et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PPARs in the Renal Regulation of Systemic Blood Pressure

(2010) Tamás Rőszer et al.   PPAR Research

Season of Conception in Rural Gambia Affects DNA Methylation at Putative Human Metastable Epialleles

(2010) Robert A. Waterland et al.   PLoS Genetics

Effect of Alcohol Consumption on CpG Methylation in the Differentially Methylated Regions ofH19andIG-DMRin Male Gametes-Implications for Fetal Alcohol Spectrum Disorders

(2009) Lillian A. Ouko et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction

(2009) Esther M. E. van Straten et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Amino acids: metabolism, functions, and nutrition

(2009) Guoyao Wu   AMINO ACIDS

Exposure of Mouse Embryos to Ethanol During Preimplantation Development: Effect on DNA Methylation in the H19 Imprinting Control Region1

(2009) Philip C. Haycock et al.   BIOLOGY OF REPRODUCTION

Maternal high fat diet during pregnancy and lactation alters hepatic expression of insulin like growth factor-2 and key microRNAs in the adult offspring

(2009) Junlong Zhang et al.   BMC GENOMICS

Epigenetics: intrauterine growth retardation (IUGR) modifies the histone code along the rat hepatic IGF-1 gene

(2009) Qi Fu et al.   FASEB JOURNAL

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

(2009) Elmar W. Tobi et al.   HUMAN MOLECULAR GENETICS

Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome

(2009) Andreas Plagemann et al.   JOURNAL OF PHYSIOLOGY-LONDON

SIRT1 and insulin resistance

(2009) Fengxia Liang et al.   Nature Reviews Endocrinology

Periconceptional Maternal Folic Acid Use of 400 µg per Day Is Related to Increased Methylation of the IGF2 Gene in the Very Young Child

(2009) Régine P. Steegers-Theunissen et al.   PLoS One

Developmental Origins of Health and Disease: Brief History of the Approach and Current Focus on Epigenetic Mechanisms

(2009) Pathik Wadhwa et al.   SEMINARS IN REPRODUCTIVE MEDICINE

Hepatic insulin resistance induced by prenatal alcohol exposure is associated with reduced PTEN and TRB3 acetylation in adult rat offspring

(2008) Xing-Hai Yao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Proline metabolism in the conceptus: implications for fetal growth and development

(2008) G. Wu et al.   AMINO ACIDS

Maternal and Postnatal Overnutrition Differentially Impact Appetite Regulators and Fuel Metabolism

(2008) Hui Chen et al.   ENDOCRINOLOGY

Methyl donor supplementation prevents transgenerational amplification of obesity

(2008) R A Waterland et al.   INTERNATIONAL JOURNAL OF OBESITY

Gestational Choline Supply Regulates Methylation of Histone H3, Expression of Histone Methyltransferases G9a (Kmt1c) and Suv39h1 (Kmt1a), and DNA Methylation of Their Genes in Rat Fetal Liver and Brain

(2008) Jessica M. Davison et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Developmental origins of disease and determinants of chromatin structure: maternal diet modifies the primate fetal epigenome

(2008) Kjersti M Aagaard-Tillery et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Effect of In Utero and Early-Life Conditions on Adult Health and Disease

(2008) Peter D. Gluckman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Persistent epigenetic differences associated with prenatal exposure to famine in humans

(2008) B. T. Heijmans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maternal obesity at conception programs obesity in the offspring

(2007) Kartik Shankar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY