Review
Biochemistry & Molecular Biology
Giovanna Nogueira da Silva Avelino Oliveira Rocha, Livia Macedo Dutra, Vitor Prates Lorenzo, Jackson Roberto Guedes da Silva Almeida
Summary: This systematic review provides an overview of the ethnomedicinal use, phytochemistry, and pharmacological activity of Annona coriacea, highlighting its potential anticancer, anti-inflammatory, antiulcer, and insecticidal properties. Comprehensive clinical trials are needed to validate the traditional practices of A. coriacea for its potential health benefits.
CHEMICO-BIOLOGICAL INTERACTIONS
(2021)
Article
Biochemistry & Molecular Biology
Phanruethai Pailee, Poonsakdi Ploypradith, Chulabhorn Mahidol, Somsak Ruchirawat, Vilailak Prachyawarakorn
Summary: Undescribed polyoxygenated cyclohexenes and twenty-one known compounds were isolated from the leaves of Uvaria dulcis Dunal. The structures of these undescribed compounds were determined by spectroscopic analysis and their cytotoxicity activity was evaluated.
Article
Food Science & Technology
Ana Luiza Coeli Cruz Ramos, Elaine Carvalho Minighin, Isabela Iunes Camilo Soares, Ricardo Manuel de Seixas Boavida Ferreira, Isabel Maria Nunes de Sousa, Rodinei Augusti, Renata Adriana Labanca, Raquel Linhares Bello de Araujo, Julio Onesio Ferreira Melo
Summary: This study evaluated the bioaccessibility of bioactive compounds in araticum fruits (peel, pulp, and seeds) from Brazil. The results showed that the food matrix directly influenced the bioaccessibility of the bioactive compounds. It also highlighted the potential of unconventionally used or consumed parts as a source of substances with biological activities, contributing to sustainability by reducing waste.
FOOD RESEARCH INTERNATIONAL
(2023)
Article
Plant Sciences
Luis M. Hernandez Fuentes, Efigenia Montalvo Gonzalez, Maria de Lourdes Garcia Magana, Luis M. Anaya Esparza, Yolanda Nolasco Gonzalez, Zuami Villagran, Sughey Gonzalez Torres, Jose Joaquin Velazquez Monreal, David Antonio Morelos Flores
Summary: The Annonaceae family, one of the oldest angiosperms, includes the genus Annona, which has the most species and edible fruits. Recent years have seen increased interest in these fruit species due to their nutritional properties and potential in treating human diseases. Mexico is their center of origin, but much is still unknown about their agronomics, postharvest handling, and potential as new crops. More research is needed to increase their commercialization, requiring interdisciplinary and interinstitutional collaboration.
Review
Chemistry, Applied
Robert Christopher
Summary: The genus Uvaria, known for its ethnobotanical uses such as tumor treatment and fever control, has plant species widely distributed in tropical Africa, Asia, and Australia. This review aims to comprehensively examine the ethnobotanical uses, biological activities, and phytochemistry of Uvaria species, providing a foundation for future studies on this genus. With many compounds from the genus Uvaria still unexplored for their biological activities, this review is expected to be useful for future phytochemical investigations on lead compounds from this genus.
NATURAL PRODUCT RESEARCH
(2022)
Article
Agricultural Engineering
Auxiliadora C. C. Barata Lopes, Marcos B. P. Camara, Aldilene S. Lima, Matheus Oliveira do Nascimento, Julia Karla A. M. Xavier, Caroline M. de Jesus, Caritas J. S. Mendonca, Andre Luis M. Carvallo, Lucilene A. Silva, Claudia Q. da Rocha
Summary: In this study, the essential oil (EO-DU) obtained from Duguetia stelechantha was extracted and characterized for the first time. The major components of the EO-DU were β-pinene, α-pinene, and spathulenol. The formulated EO microemulsion (EO-ME) showed enhanced antileishmanial activity compared to the EO-DU. This assessment provides relevant perspectives for future bioeconomy studies, considering the abundance of D. stelechantha in the Brazilian Legal Amazon and the enhanced antileishmanial potential of the extracted EO through microemulsion incorporation.
INDUSTRIAL CROPS AND PRODUCTS
(2023)
Article
Chemistry, Applied
Caroline Zanella Cagnini, Angelica Barbosa Dias, Mariana Rodrigues Vilas Boas, Fabiana Pacheco Reis Batista, Maria Graciela Iecher Faria, Jasmina Glamoclija, Marina Sokovic, Vele Tesevic, Ederlan de Souza Ferreira, Nelson Barros Colauto, Giani Andrea Linde, Zilda Cristiani Gazim
Summary: This study investigated the antimicrobial activity and chemical composition of Annona muricata leaf oleoresin extracted by supercritical CO2. The oleoresin showed high bactericidal activity against various bacteria, but low fungicidal activity. Promising applications in food, cosmetic, and pharmaceutical industries were suggested for the leaf oleoresin of A. muricata.
NATURAL PRODUCT RESEARCH
(2022)
Article
Food Science & Technology
Ana Luiza Coeli Cruz Ramos, Mauro Ramalho Silva, Henrique de Oliveira Prata Mendonca, Ana Carolina do Carmo Mazzinghy, Viviane Dias Medeiros Silva, Bruno Goncalves Botelho, Rodinei Augusti, Ricardo Manuel de Seixas Boavida Ferreira, Isabel Maria Nunes de Sousa, Paula Batista-Santos, Raquel Linhares Bello de Araujo, Julio Onesio Ferreira Melo
Summary: The Brazilian cerrado is an important biome, and araticum fruit from this region has been found to contain various beneficial metabolites. This study aimed to analyze the chemical profiles of different parts of the araticum fruit using different solvents for extraction. Ethanol was found to extract the most metabolites, and the chemical profiles varied depending on fruit part, geographic location, and extraction solvent. Araticum shows promising potential for human health, but its use in human diet remains underexplored.
FOOD RESEARCH INTERNATIONAL
(2022)
Article
Multidisciplinary Sciences
Virayu Suthiphasilp, Tharakorn Maneerat, Raymond J. Andersen, Brian O. Patrick, Stephen G. Pyne, Surat Laphookhieo
Summary: The study isolated new compounds from Desmos dumosus and found that several of them exhibited strong inhibitory activities against alpha-glucosidase.
Article
Chemistry, Applied
Bruna R. de Lima, Felipe M. A. da Silva, Elzalina R. Soares, Richardson A. de Almeida, Jessica B. Maciel, Carromberth C. Fernandes, Andre C. de Oliveira, Wanderli P. Tadei, Hector H. F. Koolen, Afonso D. L. de Souza, Maria L. B. Pinheiro
Summary: The study is the first to report the chemical composition of the essential oil from Onychopetalum periquino leaves and demonstrate its high larvicidal activity against Aedes aegypti larvae.
NATURAL PRODUCT RESEARCH
(2021)
Article
Chemistry, Applied
Desire Soh, Nkwengoua Ernestine, Emmanuella Marthe Tchana Satchet, Ulrich Dzo Defokou, Bernd Schneider, Vidari Giovanni, Barthelemy Nyasse
Summary: Two diterpenoids were isolated from Xylopia aethiopica fruits, and their antiproliferative activities were tested on various human tumor cells, with compound 2 showing significant activity against breast cancer cells and pulmonary adenocarcinoma cells.
NATURAL PRODUCT RESEARCH
(2022)
Review
Biochemistry & Molecular Biology
Wanessa Sales de Almeida, Durcilene Alves da Silva
Summary: Polysaccharide quaternization can enhance the interaction between polysaccharides and structures with negative charges, increasing their biological activity, without affecting toxicity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Applied
Marcia Moraes Cascaes, Sebastiao Gomes Silva, Jorddy Neves Cruz, Mozaniel Santana de Oliveira, Jorge Oliveira, Angelo Antonio Barbosa de Moraes, Fernando Augusto Miranda da Costa, Kaue Santana da Costa, Lidiane Diniz do Nascimento, Eloisa Helena de Aguiar Andrade
Summary: The study extracted and analyzed the essential oil of Annona exsucca DC. or Rollinia exsucca, finding sesquiterpene hydrocarbons as the predominant compounds in the March sample and monoterpenes and sesquiterpenes as dominant compounds in the September sample. Computational methods showed that some major compounds may have antimicrobial and anticancer activities.
NATURAL PRODUCT RESEARCH
(2022)
Editorial Material
Plant Sciences
Hazem S. Elshafie
Summary: This article summarizes the chemical composition and biological-pharmaceutical activities of plant essential oils (PEOs), and discusses their possible modes of action and influencing factors. It provides valuable insights into the application of PEOs.
Review
Marine & Freshwater Biology
Ting Wu, Fei Xiao, Wenli Li
Summary: Marine microorganisms produce macrolactins with various biological activities, making them potential compounds for drug development. These macrolactins are biosynthesized via a type I polyketide synthase pathway, offering opportunities for structural diversification.
MARINE LIFE SCIENCE & TECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Anis Ben Hsouna, Sabah Dhibi, Wissal Dhifi, Rania Ben Saad, Faical Brini, Najla Hfaidh, Jackson Roberto Guedes da Silva Almeida, Wissem Mnif
Summary: Lobularia maritima, commonly known as sweet alyssum, is an annual halophyte with antioxidant properties, which has been shown to protect against liver damage in animal models.
DRUG AND CHEMICAL TOXICOLOGY
(2022)
Article
Chemistry, Applied
Camila de Souza Araujo, Daniel Amando Nery, Ana Paula de Oliveira, Raimundo Goncalves De Oliveira-Junior, Larissa Araujo Rolim, Norberto Peporine Lopes, Maria Francilene de Souza Silva, Claudia do O. Pessoa, Raimundo Braz-Filho, Livia Macedo Dutra, Josean Fechine Tavares, Lucas Silva Abreu, Marcelo Sobral da Silva, Jackson Roberto Guedes da Silva Almeida
Summary: A new nor-ent-kaurene diterpene and ten other compounds were isolated from the stems of Annona vepretorum. Their chemical structures were elucidated using spectroscopic methods. The cytotoxic activity of some compounds was evaluated and found to be low.
NATURAL PRODUCT RESEARCH
(2023)
Article
Chemistry, Multidisciplinary
Ana Edileia Barbosa Pereira Leal, Erica Martins de Lavor, Ana Paula de Oliveira, Livia Macedo Dutra, Jackson de Menezes Barbosa, Cristiane dos Santos Cerqueira Alves, Roxana Braga de Andrade Teles, Raira Feitosa dos Santos, Ricardo Santana de Lima, Mario Adriano Avila Queiroz, Julianeli Tolentino de Lima, Jackson Roberto Guedes da Silva Almeida
Summary: This study evaluated the safety profile and hypolipidemic potential of the fruit peel of Passiflora cincinnata Mast. and found that the extract and flour significantly decreased lipid levels in hyperlipidemic mice.
DRUG AND CHEMICAL TOXICOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Emmanoel Costa, Leociley R. Alencar Menezes, Livia M. Dutra, Maria Lucia B. Pinheiro, Erica M. Lavor, Mariana G. Silva, Cristiane dos S. C. Alves, Jackson R. G. S. Almeida, Felipe Moura A. da Silva, Hector H. F. Koolen, Andersson Barison
Summary: This study evaluated the chemical composition and antinociceptive activity of essential oil extracted from Guatteria friesiana leaves. Seven compounds were identified, with beta-eudesmol and alpha-eudesmol mixture, and gamma-eudesmol being the major components. A new derivative named 5-hydroxy-alpha-eudesmol was isolated along with known compounds. The essential oil showed significant antinociceptive properties, likely through opioid receptors and K+-ATP channels.
ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
(2023)
Article
Fisheries
Juliano dos Santos Macedo, Carlos Eduardo Copatti, Emmanoel Vilaca Costa, Felipe Moura Araujo da Silva, Livia Macedo Dutra, Victoria Laysna dos Anjos Santos, Jackson Roberto Guedes da Silva Almeida, Marcos Tavares-Dias, Jose Fernando Bibiano Melo
Summary: This study aimed to investigate the effects of dietary supplementation with Citrus limon extract (CLE) on the growth and immune response of striped catfish juveniles. The results showed that adding 0.4 g CLE/kg feed improved the growth and immune resistance of striped catfish.
AQUACULTURE INTERNATIONAL
(2023)
Article
Biochemistry & Molecular Biology
Anne Caroline dos Santos Dantas, Michele Mirian Calixto de Lira, Livia Macedo Dutra, Cristiane Maria Souza de Castro Rodrigues, Silvio Alan Gonsalves Bonfim Reis, Rosane Nora Castro, Jackson Roberto Guedes da Silva Almeida
Summary: This study evaluated the potential photoprotective and antioxidant activity of Encholirium spectabile incorporated in O/W emulsion. The results showed that adding the extract of Encholirium spectabile in sunscreen can enhance its protective effect and maintain the stability of the emulsion.
PHOTOCHEMISTRY AND PHOTOBIOLOGY
(2023)
Article
Microbiology
Jarbas Freitas Amarante, Mateus Matiuzzi da Costa, Jackson Roberto Guedes da Silva Almeida, Helinando Pequeno de Oliveira
Summary: The use of essential oils, such as clove and cinnamon, incorporated into electrospun fibers showed promising antibacterial activity against Staphylococcus aureus. The combination of clove and cinnamon demonstrated the highest performance, with a 65% improvement in antibacterial activity.
BRAZILIAN JOURNAL OF MICROBIOLOGY
(2023)
Article
Agronomy
Brena Coutinho Muniz, Rupam Kapoor, Jackson Roberto Guedes da Silva Almeida, Carmelo Jose Albanez Bastos Filho, Fabio Sergio Barbosa da Silva
Summary: This study found that selecting the appropriate combination of AMF strains and substrates can increase the photoprotective and antioxidant activities in Hymenaea martiana leaves. Vermicompost supplementation reduced these effects, but AMF colonization significantly increased photoprotective activity, possibly due to the increased concentration of proanthocyanidins. Inoculating with AMF can improve the quality of H. martiana plants and reduce the need for vermicompost.
Article
Chemistry, Multidisciplinary
Juliane M. S. Silva, Flavia C. R. Vilar, Gabriel A. B. Lima, Elizangela M. Souza, Livia M. Dutra, Jackson R. G. S. Almeida, Larissa A. Rolim, Norberto P. Lopes, Ana P. Oliveira
Summary: The present study aimed to assess the toxic, antioxidant, and antibacterial properties of P. amboinicus essential oil. The results showed that the essential oil has weak antioxidant activity, is highly toxic against Artemia salina, and exhibits strong antibacterial activity, especially against Aeromonas hydrophila strains.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2023)
Article
Pharmacology & Pharmacy
Hamida Benfreha, Emanuella Chiara Valenca Pereira, Larissa Araujo Rolim, Nadia Chelli, Jackson Roberto Guedes da Silva Almeida, Aicha Tirtouil, Boumediene Meddah
Summary: This study examined the inhibitory potential of Lactobacillus exopolysaccharides (EPS) and Satureja calamintha extracts on enteropathogenic Escherichia coli responsible for gastroenteritis. The results showed that the hydromethanolic extracts and EPS had stronger antibacterial activity and affected the aggregation and adhesion of E. coli.
BRAZILIAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Hicham Mechqoq, Sohaib Hourfane, Mohamed El Yaagoubi, Abdallah El Hamdaoui, Fouad Msanda, Jackson Roberto Guedes da Silva Almeida, Joao Miguel Rocha, Noureddine El Aouad
Summary: This study evaluated the phytoconstituents and biological activities of four Moroccan plants. The results showed that two of these plants, Halimium antiatlanticum and Adenocarpus artemisiifolius, exhibited strong antioxidant and dermocosmetic activities, making them potential resources for traditional use by local populations or exploitation by the cosmetic industry.
Article
Medicine, Research & Experimental
Bruna B. Gouveia, Ricassio S. Barberino, Vanuzia G. Menezes, Alane P. O. Monte, Regina Lucia S. Silva, Raimundo C. Palheta, Larissa A. Rolim, Emanuella C. Pereira, Raimundo G. Oliveira, Jackson Roberto G. S. Almeida, Maria Helena T. Matos
Summary: Amburana cearensis leaf extract prevented cisplatin-induced ovarian damage through its antioxidant actions and by modulating the expression of phosphorylated PTEN and Akt proteins. This study has significant clinical implications.
IRANIAN JOURNAL OF BASIC MEDICAL SCIENCES
(2022)
Article
Biochemistry & Molecular Biology
Rafaela Santos de Melo, Silvio Alan Goncalves Bomfim Reis, Amanda Leite Guimaraes, Naiane Darklei dos Santos Silva, Joao Miguel Rocha, Noureddine El Aouad, Jackson Roberto Guedes da Silva Almeida
Summary: The study found that the leaf extract of Morus nigra L. has antioxidant and antibacterial activities, and successfully developed a topical emulsion containing the extract. The emulsion was stable in terms of pH value and viscosity, except for the spreadability, which was affected by temperature. The antioxidant activity remained stable under most conditions, but decreased significantly under 4 degrees C.
Letter
Chemistry, Multidisciplinary
Jackson Roberto Guedes da Silva Almeida, Raphael Grougnet, Lucindo Jose Quintans Junior, Sylvie Chevalier, Marc Feuilloley, Thomas Robert, Stephane Bach, Raimundo Goncalves de Oliveira Junior, Valerie Thiery, Jean-Pierre Bazureau, Florence Mongin, Marina Kritsanida, Vincent Sol, Vicente Carlos de Oliveira Costa, Nathalie Bourgougnon, Pascal Marchand, Laurent Picot
Article
Biochemistry & Molecular Biology
Hicham Mechqoq, Sohaib Hourfane, Mohamed El Yaagoubi, Abdallah El Hamdaoui, Jackson Roberto Guedes da Silva Almeida, Joao Miguel Rocha, Noureddine El Aouad
Summary: The argan tree, endemic to Morocco, is known for its therapeutic and medicinal uses. Research shows that the fruit pulp of the argan tree has potential dermocosmetic activities related to tyrosinase, collagenase, and elastase inhibitory activities.