Network Excitability Dysfunction in Alzheimer's Disease: Insights from In Vitro and In Vivo Models

Epilepsy and Cognitive Impairments in Alzheimer Disease

(2009) Jorge J. Palop   ARCHIVES OF NEUROLOGY

An update on treatment and prevention strategies for Alzheimer’s disease

(2009) Judith Neugroschl et al.   Current Neurology and Neuroscience Reports

Differential calcium signalling in neuronal-glial networks

(2009) Alexei Verkhratsky   Frontiers in Bioscience-Landmark

Spatial Learning Impairment, Enhanced CDK5/p35 Activity, and Downregulation of NMDA Receptor Expression in Transgenic Mice Expressing Tau-Tubulin Kinase 1

(2009) S. Sato et al.   JOURNAL OF NEUROSCIENCE

A Reporter of Local Dendritic Translocation Shows Plaque- Related Loss of Neural System Function in APP-Transgenic Mice

(2009) M. Meyer-Luehmann et al.   JOURNAL OF NEUROSCIENCE

Expression of Human Amyloid Precursor Protein in Rat Cortical Neurons Inhibits Calcium Oscillations

(2009) S. F. Santos et al.   JOURNAL OF NEUROSCIENCE

Deviant Ryanodine Receptor-Mediated Calcium Release Resets Synaptic Homeostasis in Presymptomatic 3xTg-AD Mice

(2009) S. Chakroborty et al.   JOURNAL OF NEUROSCIENCE

Presenilins are essential for regulating neurotransmitter release

(2009) Chen Zhang et al.   NATURE

Small molecule blockers of the Alzheimer A  calcium channel potently protect neurons from A  cytotoxicity

(2009) J. C. Diaz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice

(2009) K. V. Kuchibhotla et al.   SCIENCE

In situAbetapores in AD brain are cylindrical assembly of Abetaprotofilaments

(2008) Sadayuki Inoue   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

The Brain's Default Network

(2008) Randy L. Buckner et al.   Annals of the New York Academy of Sciences

Soluble oligomers of the amyloid β-protein impair synaptic plasticity and behavior

(2008) Dennis J. Selkoe   BEHAVIOURAL BRAIN RESEARCH

A Polymorphism in CALHM1 Influences Ca2+ Homeostasis, Aβ Levels, and Alzheimer's Disease Risk

(2008) Ute Dreses-Werringloer et al.   CELL

Amyloid   Oligomers (A 1-42 Globulomer) Suppress Spontaneous Synaptic Activity by Inhibition of P/Q-Type Calcium Currents

(2008) V. Nimmrich et al.   JOURNAL OF NEUROSCIENCE

Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: a randomised, double-blind, placebo-controlled study

(2008) Rachelle S Doody et al.   LANCET

Evaluation of Dimebon in cellular model of Huntington's disease

(2008) Jun Wu et al.   Molecular Neurodegeneration

Activation of large-conductance Ca2+-activated K+ channels depresses basal synaptic transmission in the hippocampal CA1 area in APP (swe/ind) TgCRND8 mice

(2008) Hui Ye et al.   NEUROBIOLOGY OF AGING

Mechanism of Ca2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP3 Receptor Channel Gating

(2008) King-Ho Cheung et al.   NEURON

Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks

(2008) Kishore V. Kuchibhotla et al.   NEURON

Subfield and layer-specific depletion in calbindin-D28K, calretinin and parvalbumin immunoreactivity in the dentate gyrus of amyloid precursor protein/presenilin 1 transgenic mice

(2008) M. Popović et al.   NEUROSCIENCE

APPswe mutation increases the frequency of spontaneous Ca2+-oscillations in rat hippocampal neurons

(2008) Ewa Kloskowska et al.   NEUROSCIENCE LETTERS

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

(2008) M. A. Busche et al.   SCIENCE

EEG alterations in non-demented individuals related to apolipoprotein E genotype and to risk of Alzheimer disease

(2007) N.V. Ponomareva et al.   NEUROBIOLOGY OF AGING