Reliable predictive computational toxicology methods for mixture toxicity: toward the development of innovative integrated models for environmental risk assessment

On the Use of Mixture Toxicity Assessment in REACH and the Water Framework Directive: A Review

(2011) K. Syberg et al.   HUMAN AND ECOLOGICAL RISK ASSESSMENT

Toxicological Mixture Models are Based on Inadequate Assumptions

(2010) Martina G. Vijver et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Joint Toxicity Evaluation and QSAR Modeling of Aromatic Amines and Phenols to Bacteria

(2009) G. H. Lu et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Chemical regulators have overreached

(2009) Thomas Hartung et al.   NATURE

Risk assessment of mixtures of pesticides. Current approaches and future strategies

(2009) Trine Klein Reffstrup et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

A comparison of machine learning algorithms for chemical toxicity classification using a simulated multi-scale data model

(2008) Richard Judson et al.   BMC BIOINFORMATICS

Are individual NOEC levels safe for mixtures? A study on mixture toxicity of brominated flame–retardants in the copepod Nitocra spinipes

(2008) Magnus Breitholtz et al.   CHEMOSPHERE

Integrated fuzzy concentration addition–independent action (IFCA–IA) model outperforms two-stage prediction (TSP) for predicting mixture toxicity

(2008) Zhuang Wang et al.   CHEMOSPHERE

A REVIEW OF INDEPENDENT ACTION COMPARED TO CONCENTRATION ADDITION AS REFERENCE MODELS FOR MIXTURES OF COMPOUNDS WITH DIFFERENT MOLECULAR TARGET SITES

(2008) Nina Cedergreen et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

MEASUREMENT AND MODELING OF THE TOXICITY OF BINARY MIXTURES IN THE NEMATODE CAENORHABDITIS ELEGANS—A TEST OF INDEPENDENT ACTION

(2008) Heather L. Martin et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Computational Toxicology Methods in Public Health Practice

(2008) Eugene Demchuk et al.   TOXICOLOGY MECHANISMS AND METHODS

Extrapolation Concepts for Dealing with Multiple Contamination in Environmental Risk Assessment

(2008) Rolf Altenburger et al.   Integrated Environmental Assessment and Management