Genetics of metabolic syndrome

Altered DNA Methylation and Differential Expression of Genes Influencing Metabolism and Inflammation in Adipose Tissue From Subjects With Type 2 Diabetes

(2014) E. Nilsson et al.   DIABETES

Genome-Wide DNA Methylation Analysis of Human Pancreatic Islets from Type 2 Diabetic and Non-Diabetic Donors Identifies Candidate Genes That Influence Insulin Secretion

(2014) Tasnim Dayeh et al.   PLoS Genetics

microRNAs as a New Mechanism Regulating Adipose Tissue Inflammation in Obesity and as a Novel Therapeutic Strategy in the Metabolic Syndrome

(2014) Qian Ge et al.   Journal of Immunology Research

Fatty acid binding protein 3 (fabp3) is associated with insulin, lipids and cardiovascular phenotypes of the metabolic syndrome through epigenetic modifications in a northern european family population

(2013) Yi Zhang et al.   BMC Medical Genomics

Discovery and refinement of loci associated with lipid levels

(2013) Cristen J Willer et al.   NATURE GENETICS

Single nucleotide polymorphisms (SNPs) involved in insulin resistance, weight regulation, lipid metabolism and inflammation in relation to metabolic syndrome: an epidemiological study

(2012) Cécile M Povel et al.   Cardiovascular Diabetology

CLOCK, PER2 and BMAL1 DNA Methylation: Association with Obesity and Metabolic Syndrome Characteristics and Monounsaturated Fat Intake

(2012) Fermín I. Milagro et al.   CHRONOBIOLOGY INTERNATIONAL

Genome-Wide Screen for Metabolic Syndrome Susceptibility Loci Reveals Strong Lipid Gene Contribution But No Evidence for Common Genetic Basis for Clustering of Metabolic Syndrome Traits

(2012) Kati Kristiansson et al.   Circulation-Cardiovascular Genetics

Genome-wide association studies of obesity and metabolic syndrome

(2012) Tove Fall et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The joint effect of cigarette smoking and polymorphisms on LRP5, LEPR, near MC4R and SH2B1 genes on metabolic syndrome susceptibility in Taiwan

(2012) Chuan-Wei Yang et al.   MOLECULAR BIOLOGY REPORTS

Common variant (rs9939609) in the FTO gene is associated with metabolic syndrome

(2012) Donghao Zhou et al.   MOLECULAR BIOLOGY REPORTS

Meta-analysis identifies common variants associated with body mass index in east Asians

(2012) Wanqing Wen et al.   NATURE GENETICS

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways

(2012) Robert A Scott et al.   NATURE GENETICS

MicroRNAs in metabolism and metabolic disorders

(2012) Veerle Rottiers et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Effects of 34 Risk Loci for Type 2 Diabetes or Hyperglycemia on Lipoprotein Subclasses and Their Composition in 6,580 Nondiabetic Finnish Men

(2011) A. Stancakova et al.   DIABETES

A Bivariate Genome-Wide Approach to Metabolic Syndrome: STAMPEED Consortium

(2011) A. T. Kraja et al.   DIABETES

Genome-wide survey reveals predisposing diabetes type 2-related DNA methylation variations in human peripheral blood

(2011) Gidon Toperoff et al.   HUMAN MOLECULAR GENETICS

Association of variations in the FTO, SCG3 and MTMR9 genes with metabolic syndrome in a Japanese population

(2011) Kikuko Hotta et al.   JOURNAL OF HUMAN GENETICS

Genetic variants in FTO associated with metabolic syndrome: a meta- and gene-based analysis

(2011) Haina Wang et al.   MOLECULAR BIOLOGY REPORTS

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

(2011) Tuomas O Kilpeläinen et al.   NATURE GENETICS

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci

(2011) Jaspal S Kooner et al.   NATURE GENETICS

A Phenomics-Based Strategy Identifies Loci on APOC1, BRAP, and PLCG1 Associated with Metabolic Syndrome Phenotype Domains

(2011) Christy L. Avery et al.   PLoS Genetics

Genome-Wide Association Analysis Identifies Variants Associated with Nonalcoholic Fatty Liver Disease That Have Distinct Effects on Metabolic Traits

(2011) Elizabeth K. Speliotes et al.   PLoS Genetics

Association of a Cyclin-Dependent Kinase 5 Regulatory Subunit-Associated Protein 1-Like 1 (CDKAL1) Polymorphism With Elevated Hemoglobin A1c Levels and the Prevalence of Metabolic Syndrome in Japanese Men: Interaction With Dietary Energy Intake

(2010) K. Miyaki et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Insulin Resistance in Obesity as the Underlying Cause for the Metabolic Syndrome

(2010) Emily J. Gallagher et al.   MOUNT SINAI JOURNAL OF MEDICINE

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

(2010) Iris M Heid et al.   NATURE GENETICS

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

(2010) Elizabeth K Speliotes et al.   NATURE GENETICS

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

(2010) Richa Saxena et al.   NATURE GENETICS

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

(2010) Josée Dupuis et al.   NATURE GENETICS

Overexpression of Fto leads to increased food intake and results in obesity

(2010) Chris Church et al.   NATURE GENETICS

A Genome-Wide Association Study of the Metabolic Syndrome in Indian Asian Men

(2010) Delilah Zabaneh et al.   PLoS One

Association of rs780094 in GCKR with Metabolic Traits and Incident Diabetes and Cardiovascular Disease: The ARIC Study

(2010) Mark Bi et al.   PLoS One

Harmonizing the Metabolic Syndrome

(2009) K.G.M.M. Alberti et al.   CIRCULATION

Association of the FTO gene with obesity and the metabolic syndrome is independent of the IRS-2 gene in the female population of Southern France

(2009) R. Attaoua et al.   DIABETES & METABOLISM

Inactivation of the Fto gene protects from obesity

(2009) Julia Fischer et al.   NATURE

“The Linosa Study”: Epidemiological and heritability data of the metabolic syndrome in a Caucasian genetic isolate

(2009) A. Bellia et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Metabolic syndrome and risk of incident diabetes: findings from the European Prospective Investigation into Cancer and Nutrition-Potsdam Study

(2008) Earl S Ford et al.   Cardiovascular Diabetology

Association between the FTO rs9939609 polymorphism and the metabolic syndrome in a non-Caucasian multi-ethnic sample

(2008) Salam A Al-Attar et al.   Cardiovascular Diabetology

Genetic Variants of FTO Influence Adiposity, Insulin Sensitivity, Leptin Levels, and Resting Metabolic Rate in the Quebec Family Study

(2008) R. Do et al.   DIABETES

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

(2008) Eleftheria Zeggini et al.   NATURE GENETICS

Newly identified loci that influence lipid concentrations and risk of coronary artery disease

(2008) Cristen J Willer et al.   NATURE GENETICS

Common genetic variation near MC4R is associated with waist circumference and insulin resistance

(2008) John C Chambers et al.   NATURE GENETICS

Genome-wide Linkage Scan for the Metabolic Syndrome: The GENNID Study

(2008) Karen L. Edwards et al.   Obesity

Association of the MC4R V103I Polymorphism With the Metabolic Syndrome: The KORA Study

(2008) Iris M. Heid et al.   Obesity