Poly- and autoreactivity of HIV-1 bNAbs: implications for vaccine design
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Title
Poly- and autoreactivity of HIV-1 bNAbs: implications for vaccine design
Authors
Keywords
HIV-1, Antibody, Immunological tolerance, Polyreactivity, Autoreactivity
Journal
Retrovirology
Volume 15, Issue 1, Pages -
Publisher
Springer Nature
Online
2018-07-28
DOI
10.1186/s12977-018-0435-0
References
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Note: Only part of the references are listed.- Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1
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- (2017) Viktoriya Dubrovskaya et al. PLoS Pathogens
- Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design
- (2016) Dennis R. Burton et al. Annual Review of Immunology
- Complex Antigens Drive Permissive Clonal Selection in Germinal Centers
- (2016) Masayuki Kuraoka et al. IMMUNITY
- Germinal centers and autoimmune disease in humans and mice
- (2016) Anthony L DeFranco IMMUNOLOGY AND CELL BIOLOGY
- Clonal redemption of autoantibodies by somatic hypermutation away from self-reactivity during human immunization
- (2016) Joanne H. Reed et al. JOURNAL OF EXPERIMENTAL MEDICINE
- HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism
- (2016) Todd Bradley et al. JOURNAL OF IMMUNOLOGY
- Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice
- (2016) Andrew T. McGuire et al. Nature Communications
- Immunization for HIV-1 Broadly Neutralizing Antibodies in Human Ig Knockin Mice
- (2015) Pia Dosenovic et al. CELL
- Autoantibodies in systemic autoimmune diseases: specificity and pathogenicity
- (2015) Jolien Suurmond et al. JOURNAL OF CLINICAL INVESTIGATION
- B Cell–Intrinsic CD84 and Ly108 Maintain Germinal Center B Cell Tolerance
- (2015) Eric B. Wong et al. JOURNAL OF IMMUNOLOGY
- An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1
- (2014) Mattia Bonsignori et al. JOURNAL OF CLINICAL INVESTIGATION
- Enhanced Antibody Responses to an HIV-1 Membrane-Proximal External Region Antigen in Mice Reconstituted with Cultured Lymphocytes
- (2014) T. M. Holl et al. JOURNAL OF IMMUNOLOGY
- Polyreactivity and Autoreactivity among HIV-1 Antibodies
- (2014) Mengfei Liu et al. JOURNAL OF VIROLOGY
- Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity
- (2014) Z. Sabouri et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Conformational dynamics of single HIV-1 envelope trimers on the surface of native virions
- (2014) J. B. Munro et al. SCIENCE
- Prevalence of broadly neutralizing antibody responses during chronic HIV-1 infection
- (2013) Peter Hraber et al. AIDS
- HIV-1 neutralizing antibodies: understanding nature's pathways
- (2013) John R. Mascola et al. IMMUNOLOGICAL REVIEWS
- Identification of autoantigens recognized by the 2F5 and 4E10 broadly neutralizing HIV-1 antibodies
- (2013) Guang Yang et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Induction of HIV-1 Broad Neutralizing Antibodies in 2F5 Knock-in Mice: Selection against Membrane Proximal External Region-Associated Autoreactivity Limits T-Dependent Responses
- (2013) L. Verkoczy et al. JOURNAL OF IMMUNOLOGY
- Immune Tolerance Negatively Regulates B Cells in Knock-In Mice Expressing Broadly Neutralizing HIV Antibody 4E10
- (2013) C. Doyle-Cooper et al. JOURNAL OF IMMUNOLOGY
- Common Tolerance Mechanisms, but Distinct Cross-Reactivities Associated with gp41 and Lipids, Limit Production of HIV-1 Broad Neutralizing Antibodies 2F5 and 4E10
- (2013) Y. Chen et al. JOURNAL OF IMMUNOLOGY
- Broadly Neutralizing Antibody PGT121 Allosterically Modulates CD4 Binding via Recognition of the HIV-1 gp120 V3 Base and Multiple Surrounding Glycans
- (2013) Jean-Philippe Julien et al. PLoS Pathogens
- Elimination of Germinal-Center-Derived Self-Reactive B Cells Is Governed by the Location and Concentration of Self-Antigen
- (2012) Tyani D. Chan et al. IMMUNITY
- Shaping of Human Germline IgH Repertoires Revealed by Deep Sequencing
- (2012) K. Larimore et al. JOURNAL OF IMMUNOLOGY
- B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study
- (2012) Barton F Haynes et al. NATURE BIOTECHNOLOGY
- Early Postnatal B Cell Ontogeny and Antibody Repertoire Maturation in the Opossum, Monodelphis domestica
- (2012) Xinxin Wang et al. PLoS One
- Complex-type N-glycan recognition by potent broadly neutralizing HIV antibodies
- (2012) H. Mouquet et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Central B-Cell Tolerance: Where Selection Begins
- (2012) R. Pelanda et al. Cold Spring Harbor Perspectives in Biology
- Rescue of HIV-1 Broad Neutralizing Antibody-Expressing B Cells in 2F5 VH x VL Knockin Mice Reveals Multiple Tolerance Controls
- (2011) L. Verkoczy et al. JOURNAL OF IMMUNOLOGY
- Differential Reactivity of Germ Line Allelic Variants of a Broadly Neutralizing HIV-1 Antibody to a gp41 Fusion Intermediate Conformation
- (2011) S. M. Alam et al. JOURNAL OF VIROLOGY
- The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4+ T Cell Decline and High Viral Load during Acute Infection
- (2011) E. S. Gray et al. JOURNAL OF VIROLOGY
- Broad neutralization coverage of HIV by multiple highly potent antibodies
- (2011) Laura M. Walker et al. NATURE
- Characteristics of the Earliest Cross-Neutralizing Antibody Response to HIV-1
- (2011) Iliyana Mikell et al. PLoS Pathogens
- Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation
- (2010) Hugo Mouquet et al. NATURE
- Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance
- (2009) L. Verkoczy et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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