Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in Th1Th17 cells and identifies Peroxisome Proliferator-Activated Receptor Gamma as an intrinsic negative regulator of viral replication

KLF11 mediates PPARγ cerebrovascular protection in ischaemic stroke

(2013) Ke-Jie Yin et al.   BRAIN

Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs

(2013) Christine Katlama et al.   LANCET

A Pilot Study of Telmisartan for Visceral Adiposity in HIV Infection: The Metabolic Abnormalities, Telmisartan, and HIV Infection (MATH) Trial

(2013) Jordan E. Lake et al.   PLoS One

The TGF -induced phosphorylation and activation of p38 mitogen-activated protein kinase is mediated by MAP3K4 and MAP3K10 but not TAK1

(2013) G. P. Sapkota   Open Biology

A role for cytomegalovirus-specific CD4+CX3CR1+ T cells and cytomegalovirus-induced T-cell immunopathology in HIV-associated atherosclerosis

(2012) Karim Sacre et al.   AIDS

PTPN13/PTPL1: An Important Regulator of Tumor Aggressiveness

(2012) Gilles Freiss et al.   Anti-Cancer Agents in Medicinal Chemistry

Distinct gene-expression profiles associated with the susceptibility of pathogen-specific CD4 T cells to HIV-1 infection

(2012) H. Hu et al.   BLOOD

Melanoma cell adhesion molecule identifies encephalitogenic T lymphocytes and promotes their recruitment to the central nervous system

(2012) Catherine Larochelle et al.   BRAIN

Intrinsic Cellular Defenses against Human Immunodeficiency Viruses

(2012) Daniel Blanco-Melo et al.   IMMUNITY

Redefining the Viral Reservoirs that Prevent HIV-1 Eradication

(2012) Evelyn Eisele et al.   IMMUNITY

The Short Isoform of the CEACAM1 Receptor in Intestinal T Cells Regulates Mucosal Immunity and Homeostasis via Tfh Cell Induction

(2012) Lanfen Chen et al.   IMMUNITY

Coexpression of CCR6 and CD146 (MCAM) is a marker of effector memory T-helper 17 cells

(2012) Taisuke KAMIYAMA et al.   JOURNAL OF DERMATOLOGY

Revealing the role of CD4+T cells in viral immunity: Figure 1.

(2012) Andrea J. Sant et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Induction and molecular signature of pathogenic TH17 cells

(2012) Youjin Lee et al.   NATURE IMMUNOLOGY

Peroxisome proliferator-activated receptor (PPAR)  and -  regulate IFN  and IL-17A production by human T cells in a sex-specific way

(2012) M. A. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Thiazolidinediones and PPARγ agonists: time for a reassessment

(2012) Bertrand Cariou et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Exon Level Transcriptomic Profiling of HIV-1-Infected CD4+ T Cells Reveals Virus-Induced Genes and Host Environment Favorable for Viral Replication

(2012) Michaël Imbeault et al.   PLoS Pathogens

Epithelial adhesion molecules can inhibit HIV-1-specific CD8+ T-cell functions

(2011) H. Streeck et al.   BLOOD

Restriction of HIV-1 replication in macrophages and CD4+ T cells from HIV controllers

(2011) A. Saez-Cirion et al.   BLOOD

Nuclear receptors: TH 17 cell control from within

(2011) L. Klotz et al.   FEBS LETTERS

An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation

(2011) R. Yagi et al.   INTERNATIONAL IMMUNOLOGY

CD4+ T cells from elite controllers resist HIV-1 infection by selective upregulation of p21

(2011) Huabiao Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Cell-penetrating peptides can confer biological function: Regulation of inflammatory cytokines in human monocytes by MK2 inhibitor peptides

(2011) Jamie L. Brugnano et al.   JOURNAL OF CONTROLLED RELEASE

Memory CCR6+CD4+ T Cells Are Preferential Targets for Productive HIV Type 1 Infection Regardless of Their Expression of Integrin  7

(2011) P. Monteiro et al.   JOURNAL OF IMMUNOLOGY

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

(2011) Nadine Laguette et al.   NATURE

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

(2011) Kasia Hrecka et al.   NATURE

A look at HIV journey

(2011) Fabien Blanchet et al.   Current Opinion in HIV and AIDS

Epac: Defining a New Mechanism for cAMP Action

(2010) Martijn Gloerich et al.   Annual Review of Pharmacology and Toxicology

KRAB Zinc Finger Protein ZNF382 Is a Proapoptotic Tumor Suppressor That Represses Multiple Oncogenes and Is Commonly Silenced in Multiple Carcinomas

(2010) Y. Cheng et al.   CANCER RESEARCH

Signaling through the P38 and ERK pathways: a common link between HIV replication and the immune response

(2010) Robert L. Furler et al.   IMMUNOLOGIC RESEARCH

Preferential infection and depletion ofMycobacterium tuberculosis–specific CD4 T cells after HIV-1 infection

(2010) Christof Geldmacher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Genome-Wide RNA Interference in Drosophila Cells Identifies G Protein-Coupled Receptor Kinase 2 as a Conserved Regulator of NF- B Signaling

(2010) S. Valanne et al.   JOURNAL OF IMMUNOLOGY

Multiple‐Cohort Genetic Association Study Reveals CXCR6 as a New Chemokine Receptor Involved in Long‐Term Nonprogression to AIDS

(2010) Sophie Limou et al.   JOURNAL OF INFECTIOUS DISEASES

T-bet represses TH17 differentiation by preventing Runx1-mediated activation of the gene encoding RORγt

(2010) Vanja Lazarevic et al.   NATURE IMMUNOLOGY

Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells

(2010) R Puca et al.   ONCOGENE

HIV Persistence and the Prospect of Long-Term Drug-Free Remissions for HIV-Infected Individuals

(2010) D. Trono et al.   SCIENCE

Th17 lineage commitment and HIV-1 pathogenesis

(2010) Petronela Ancuta et al.   Current Opinion in HIV and AIDS

PPARγ and LXR Signaling Inhibit Dendritic Cell-Mediated HIV-1 Capture and trans-Infection

(2010) Timothy M. Hanley et al.   PLoS Pathogens

NetPath: a public resource of curated signal transduction pathways

(2010) Kumaran Kandasamy et al.   GENOME BIOLOGY

Peroxisome proliferator-activated receptor-γ activation suppresses HIV-1 replication in an animal model of encephalitis

(2009) Raghava Potula et al.   AIDS

IL-17 and Th17 Cells

(2009) Thomas Korn et al.   Annual Review of Immunology

Transcriptional profiling reveals developmental relationship and distinct biological functions of CD16+ and CD16- monocyte subsets

(2009) Petronela Ancuta et al.   BMC GENOMICS

Transcriptional regulatory networks in Th17 cell differentiation

(2009) Liang Zhou et al.   CURRENT OPINION IN IMMUNOLOGY

Heterogeneity of CD4+ memory T cells: Functional modules for tailored immunity

(2009) Federica Sallusto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Genome-wide Short Hairpin RNA Screening of Jurkat T-cells for Human Proteins Contributing to Productive HIV-1 Replication

(2009) Man Lung Yeung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The nuclear receptor PPARγ selectively inhibits Th17 differentiation in a T cell–intrinsic fashion and suppresses CNS autoimmunity

(2009) Luisa Klotz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Peripheral Blood CCR4+CCR6+ and CXCR3+CCR6+ CD4+ T Cells Are Highly Permissive to HIV-1 Infection

(2009) A. Gosselin et al.   JOURNAL OF IMMUNOLOGY

The CDK Inhibitor p21Cip1/WAF1 Is Induced by Fc R Activation and Restricts the Replication of Human Immunodeficiency Virus Type 1 and Related Primate Lentiviruses in Human Macrophages

(2009) A. Bergamaschi et al.   JOURNAL OF VIROLOGY

The roles of CCR6 in migration of Th17 cells and regulation of effector T-cell balance in the gut

(2009) C Wang et al.   Mucosal Immunology

C-C chemokine receptor 6–regulated entry of TH-17 cells into the CNS through the choroid plexus is required for the initiation of EAE

(2009) Andrea Reboldi et al.   NATURE IMMUNOLOGY

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

CORUM: the comprehensive resource of mammalian protein complexes—2009

(2009) Andreas Ruepp et al.   NUCLEIC ACIDS RESEARCH

Host Cell Factors in HIV Replication: Meta-Analysis of Genome-Wide Studies

(2009) Frederic D. Bushman et al.   PLoS Pathogens

Autocrine Production of β-Chemokines Protects CMV-Specific CD4+ T Cells from HIV Infection

(2009) Joseph P. Casazza et al.   PLoS Pathogens

Up-Regulation of Activating Transcription Factor-5 Suppresses SAP Expression to Activate T Cells in Hemophagocytic Syndrome Associated with Epstein-Barr Virus Infection and Immune Disorders

(2008) Huai-Chia Chuang et al.   AMERICAN JOURNAL OF PATHOLOGY

Emerging Concepts in the Immunopathogenesis of AIDS

(2008) Daniel C. Douek et al.   Annual Review of Medicine

Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication

(2008) Renate König et al.   CELL

Knockdown Screens to Knockout HIV-1

(2008) Stephen P. Goff   CELL

Genome-Scale RNAi Screen for Host Factors Required for HIV Replication

(2008) Honglin Zhou et al.   Cell Host & Microbe

A Modular Analysis Framework for Blood Genomics Studies: Application to Systemic Lupus Erythematosus

(2008) Damien Chaussabel et al.   IMMUNITY

Human interleukin 17–producing cells originate from a CD161+CD4+T cell precursor

(2008) Lorenzo Cosmi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Mutations inSTAT3andIL12RB1impair the development of human IL-17–producing T cells

(2008) Ludovic de Beaucoudrey et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Early Depletion ofMycobacterium tuberculosis–Specific T Helper 1 Cell Responses after HIV‐1 Infection

(2008) Christof Geldmacher et al.   JOURNAL OF INFECTIOUS DISEASES

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

(2008) Stuart J. D. Neil et al.   NATURE

The differentiation of human TH-17 cells requires transforming growth factor-β and induction of the nuclear receptor RORγt

(2008) Nicolas Manel et al.   NATURE IMMUNOLOGY

The G-protein-coupled receptor kinase 5 inhibits NF B transcriptional activity by inducing nuclear accumulation of I B 

(2008) D. Sorriento et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Host Proteins Required for HIV Infection Through a Functional Genomic Screen

(2008) Abraham L. Brass et al.   SCIENCE

PGJ2 antagonizes NF-κB-induced HIV-1 LTR activation in colonic epithelial cells

(2008) Mélissa Boisvert et al.   VIROLOGY